In this issue of Blood Cancer Journal, Ailawadhi et al. explored the sociodemographic variables impacting differences in access and utilization of autologous stem cell transplantation (ASCT) within each of the U.S. census defined racial-ethnic groups [1]. Using the National Cancer Database, records of 111,799 unique patients with multiple myeloma between 2004 and 2013 and who received ASCT were included.

在本期《血癌杂志》中，Ailawadhi等人探讨了影响每个美国人口普查定义的种族群体中自体干细胞移植（ASCT）获取和利用差异的社会人口学变量。使用国家癌症数据库，纳入了2004年至2013年间111799名接受ASCT治疗的多发性骨髓瘤患者的记录。

Non-Hispanic White (NHW) patients comprised most of the cohort (77.5%), while 15.1% were non-Hispanic Black, 5.2% were Hispanic and 2% were non-Hispanic Asian. Ailawadhi and coauthors identified several consistent themes across the racial-ethnic groups which impacted the utilization of transplant. Over the decade of patients analyzed, there was clear uptrend in the proportions of patients transplanted for all patient groups except for the non-Hispanic Asian cohort.

非西班牙裔白人（NHW）患者占队列的大部分（77.5%），而非西班牙裔黑人占15.1%，西班牙裔占5.2%，非西班牙裔亚洲人占2%。Ailawadhi和合著者确定了跨种族群体的几个一致主题，这些主题影响了移植的利用。在分析的十年患者中，除非西班牙裔亚洲人群外，所有患者组移植的患者比例均呈明显上升趋势。

The reasons for the discrepancy among non-Hispanic Asian patients are unclear, but this was notably the smallest sub-population consisting of just 1.8% of the patients analyzed. Generally, patients treated at an academic or research facility, patients who had to traverse greater distance from the treatment facility and those with private payor insurance were more likely to receive ASCT.

非西班牙裔亚洲患者之间存在差异的原因尚不清楚，但这显然是最小的亚人群，仅占所分析患者的1.8%。一般来说，在学术或研究机构接受治疗的患者，必须穿越距离治疗机构更远的患者以及拥有私人支付保险的患者更有可能接受ASCT。

Higher income increased the odds of ASCT for NHW and Hispanic patients but not for Black or Asian patients. Higher Charlston Comorbidity Index score and older age decreased the odds of receiving autologous stem cell transplantation among all racial ethnic groups.Inequity in access to healthcare resources is an unassailable reality [2].

较高的收入增加了NHW和西班牙裔患者ASCT的几率，但黑人或亚裔患者则没有。Charlston合并症指数评分较高和年龄较大降低了所有种族群体接受自体干细胞移植的几率。获得医疗资源的不平等是一个不争的现实（2）。

Interwoven in the healthcare delivery models are geographic location, patients’ specific socioeconomic status and racial-ethnic disparities, which significantly impact care [2,3,4]. Multiple mye.

医疗保健模式中交织的是地理位置，患者特定的社会经济地位和种族差异，这对护理产生了重大影响[2，3，4]。多个mye。

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National Institutes of Health. Using population descriptors in genetics and genomics research: a new framework for an evolving field. Reports funded by National Institutes of Health. Washington (DC): The National Academies Collection; 2023.Download referencesAuthor informationAuthors and AffiliationsDivision of Hematology, Mayo Clinic, Rochester, MN, USAJoselle Madonna CookAuthorsJoselle Madonna CookView author publicationsYou can also search for this author in.

国立卫生研究院。在遗传学和基因组学研究中使用人口描述符：一个不断发展的领域的新框架。由美国国立卫生研究院资助的报告。华盛顿（DC）：国家学院收藏；。

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Reprints and permissionsAbout this articleCite this articleCook, J.M. Racial disparities in multiple myeloma and access to stem cell transplantation.

转载和许可本文引用本文Cook，J.M。多发性骨髓瘤和干细胞移植的种族差异。

Blood Cancer J. 14, 120 (2024). https://doi.org/10.1038/s41408-024-01097-5Download citationReceived: 08 May 2024Revised: 26 June 2024Accepted: 10 July 2024Published: 22 July 2024DOI: https://doi.org/10.1038/s41408-024-01097-5Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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