Pharming公布2026年第二季度及上半年财务业绩并修订全年指引；Joenja势头强劲，近期临床数据读出将支持更广泛的治疗应用-动脉网

Pharming reports second quarter and first half 2026 financial results and revises year-end guidance; strong Joenja momentum and near-term clinical readouts to support broader therapeutic use

GlobeNewswire 等信源发布 2026-07-30 05:00

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For investor audiences and media only

仅限投资者和媒体

Second quarter 2026 total revenues decreased by 3% to US$90.2 million, compared to the second quarter 2025

2026年第二季度总营收为9,020万美元，较2025年第二季度下降3%

RUCONEST® revenue was US$72.3 million, a 10% decrease compared to the second quarter 2025 and a 24% increase compared to the first quarter 2026, with active patient base 93% of year-ago and strong new patient enrollments

RUCONEST® 的收入为7,230万美元，较2025年第二季度下降10%，较2026年第一季度增长24%；活跃患者基数为去年同期的93%，新患者入组情况强劲。

Joenja® revenue was US$17.9 million, a 40% increase compared to the second quarter 2025, reflecting continued strong U.S. and international growth, with first European launch in Germany after quarter-end

Joenja® 的收入为1,790万美元，较2025年第二季度增长40%，反映出美国及国际市场持续强劲的增长势头，且在季度结束后于德国完成了欧洲市场的首次上市。

Second quarter operating profit amounted to US$1.3 million compared to US$10.8 million in the second quarter 2025, impacted by manufacturing-related inventory impairments, lower revenue and France site closure

第二季度营业利润为130万美元，而2025年第二季度为1,080万美元，受到与制造相关的存货减值、收入下降以及法国工厂关闭的影响。

Plans to report clinical data with leniolisib in significantly larger CVID patient populations in the fourth quarter 2026

计划在2026年第四季度报告在更大规模的常见变异型免疫缺陷病（CVID）患者人群中开展的leniolisib临床试验数据

Updates 2026 total revenue guidance to US$375 million - US$395 million, reflecting a US$30 million reduction, and improves operating expense guidance by US$15 million to US$315 million - US$320 million

将2026年全年营收指引下调3,000万美元，至3.75亿美元–3.95亿美元；同时将运营费用指引优化1,500万美元，至3.15亿美元–3.20亿美元

Pharming to host a conference call today at 13:30 CEST (7:30 am EDT)

Pharming 将于今天欧洲中部夏令时间 13:30（美国东部夏令时间上午 7:30）举行电话会议

Leiden, the Netherlands, July 30, 2026:

荷兰莱顿，2026年7月30日：

Pharming Group N.V. (Euronext Amsterdam: PHARM/Nasdaq: PHAR) presents its preliminary (unaudited) financial report for the second quarter and first half year ended June 30, 2026.

Pharming Group N.V.（泛欧交易所阿姆斯特丹：PHARM/纳斯达克：PHAR）公布截至2026年6月30日的第二季度及上半年初步（未经审计）财务报告。

Chief Executive Officer, Fabrice Chouraqui, commented:

首席执行官法布里斯·舒拉基评论道：

“While we have lowered our full-year revenue guidance, we are encouraged by the resilience of RUCONEST, a year after the launch of the first oral on-demand HAE treatment. The active patient base remained at 93% of year ago levels, and RUCONEST continues to be a cornerstone on-demand treatment for high-burden HAE patients.

“尽管我们下调了全年收入指引，但在首款口服按需HAE治疗药物推出一年后，RUCONEST展现出的韧性令我们备受鼓舞。活跃患者基数保持在去年同期水平的93%，RUCONEST继续作为高负担HAE患者按需治疗的基石。”

Supported by strong new patient enrollments in the second quarter, we expect RUCONEST revenues to stabilize and return to growth during the second half of 2026..

在第二季度强劲的新患者入组支持下，我们预计RUCONEST的收入将在2026年下半年企稳并恢复增长。

Joenja (leniolisib) continued to build momentum in APDS, supported by expansion into additional geographies. Beyond APDS, we are encouraged by the potential for leniolisib in broader populations with primary immunodeficiencies, including CVID, where the PI3Kδ pathway is seen as a key driver of immune dysregulation, and we look forward to reporting data from two clinical trials in the fourth quarter of 2026..

Joenja（leniolisib）在APDS治疗领域持续势头强劲，这得益于其市场覆盖范围扩展至更多地区。除APDS外，我们对leniolisib在更广泛的原发性免疫缺陷患者群体（包括CVID）中的应用潜力感到鼓舞；在这些疾病中，PI3Kδ通路被视为免疫失调的关键驱动因素。我们期待在2026年第四季度公布两项临床试验的数据。

As we continue to implement a more disciplined operating model, reflected in our improved full-year operating expense guidance, Pharming is evolving into a more diversified rare disease company with a high-value pipeline that has the potential to materially increase our scale and strengthen our long-term growth profile.”.

“随着我们持续推进更加规范的运营模式（这体现在我们对全年运营费用指引的改善上），Pharming 正在转型为一家更具多元化的罕见病公司，拥有高价值的产品管线，有望显著提升我们的规模并增强长期增长前景。”

Second quarter and first half 2026 highlights

2026年第二季度及上半年亮点

Commercialized assets

商业化资产

RUCONEST marketed for the treatment of acute HAE attacks

RUCONEST 获批用于治疗急性遗传性血管性水肿发作

RUCONEST revenue in the second quarter of 2026 was US$72.3 million, a 10% decrease compared to the second quarter of 2025 and a 24% increase compared to the first quarter of 2026. Revenue for the first half of 2026 was US$130.7 million, a 12% decrease compared to the same period in 2025.

2026年第二季度，RUCONEST的收入为7,230万美元，较2025年第二季度下降10%，较2026年第一季度增长24%。2026年上半年的收入为1.307亿美元，较2025年同期下降12%。

RUCONEST revenue in the current quarter compared to the second quarter of 2025 was impacted by market dynamics in the U.S. (reducing revenue by 6%), inventory drawdowns at U.S. specialty pharmacy customers, and the completion of the planned withdrawal from non-U.S. markets.

与2025年第二季度相比，本季度RUCONEST的收入受到美国市场动态（导致收入减少6%）、美国专业药房客户库存下降以及按计划完成退出非美国市场的影响。

With its differentiated efficacy, reliability and rapid onset of action via IV administration, RUCONEST remains a trusted on-demand treatment option for high-burden patients experiencing more severe or frequent attacks who have failed other on-demand medications, despite increasing competition. The overwhelming majority of RUCONEST patients remain on therapy with the active patient base at 93% of year ago levels.

凭借差异化的疗效、可靠性以及静脉给药带来的快速起效特点，尽管面临日益激烈的竞争，RUCONEST 仍然是那些遭受更严重或更频繁发作、且其他按需治疗药物失败的高负担患者所信赖的按需治疗选择。绝大多数 RUCONEST 患者仍在持续接受治疗，活跃患者数量维持在一年前水平的 93%。

Notably, we achieved a significant increase in new patient enrollments and continued to add new prescribers in the current quarter, indicating continued physician confidence and improvement in underlying performance..

值得注意的是，我们在本季度实现了新患者入组的显著增长，并持续新增处方医生，这表明医生对我们的信心持续增强，基础业绩也在不断改善。

Joenja (leniolisib) marketed for the treatment of APDS

Joenja（leniolisib）已上市，用于治疗APDS

Joenja revenue increased to US$17.9 million in the second quarter of 2026, a 40% increase compared to the second quarter of 2025. Revenue for the first half of 2026 was US$32.0 million, a 37% increase compared to the same period in 2025.

Joenja在2026年第二季度的营收增至1,790万美元，较2025年第二季度增长40%。2026年上半年营收为3,200万美元，较2025年同期增长37%。

Year-over-year revenue growth in the current quarter was driven by a strong increase in patients on paid therapy in the U.S., inventory normalization at U.S. specialty pharmacy customers following greater drawdowns in the first quarter, and increased demand in international markets.

本季度营收同比增长主要得益于美国付费治疗患者数量的强劲增长、美国专科药房客户在第一季度大幅去库存后库存回归正常水平，以及国际市场需求的增加。

The U.S. market contributed 86% of second quarter revenues, while the EU and Rest of World contributed 14%.

美国市场贡献了第二季度收入的86%，而欧盟和世界其他地区贡献了14%。

As of June 30, 2026, 132 patients were on paid therapy in the U.S., representing a 16% increase from the 114 patients at the end of the second quarter of 2025 and an increase of 5 patients during the quarter.

截至2026年6月30日，美国有132名患者正在接受付费治疗，较2025年第二季度末的114名患者增长16%，本季度增加5名患者。

APDS patient finding

APDS 患者发现

As of June 30, 2026, we have identified 1,042 diagnosed APDS patients of all ages globally, including 298 patients in the U.S. and 387 in core markets outside of the U.S. Of the identified patients in the U.S., 198 patients are 12 years of age or older and currently eligible for treatment with Joenja, while 60 are between 4 and 11 years of age..

截至2026年6月30日，我们在全球范围内已确认1,042名各年龄段的确诊APDS患者，其中包括美国的298名患者以及美国以外核心市场的387名患者。在美国已确认的患者中，198名患者年龄在12岁及以上，目前符合接受Joenja治疗的条件；另有60名患者年龄在4至11岁之间。

Joenja (leniolisib) development

Joenja（leniolisib）的开发

Leniolisib for APDS

Leniolisib 用于治疗 APDS

As of June 30, 2026, there are 188 APDS patients in either a leniolisib Expanded Access Program (compassionate use), an ongoing clinical study, or a paid access program.

截至2026年6月30日，共有188名APDS患者参与了leniolisib的扩大访问计划（同情用药）、正在进行的临床研究或付费访问计划。

Pediatric label expansion

儿科适应症扩展

On June 4, 2026, we announced that the U.S. Food and Drug Administration (FDA) had accepted our resubmitted supplemental New Drug Application (sNDA) seeking approval for Joenja as a treatment for children aged 4 to 11 years with APDS. Following the Complete Response Letter (CRL) received on January 30, 2026, and a subsequent Type A meeting with the FDA on March 26, 2026, the resubmission seeks approval of 40 mg and 50 mg twice-daily dosing for pediatric patients weighing 27 kg or more, who represent a meaningful proportion of the identified pediatric patient population.

2026年6月4日，我们宣布美国食品药品监督管理局（FDA）已受理我们重新提交的补充新药申请（sNDA），该申请旨在寻求批准将Joenja用于治疗4至11岁的活化磷酸肌醇3-激酶δ综合征（APDS）儿童患者。在2026年1月30日收到完全回应函（CRL）并于2026年3月26日与FDA召开A类会议之后，此次重新提交的申请寻求批准对体重为27公斤或以上的儿科患者采用40毫克和50毫克每日两次的给药方案，这类患者占已识别儿科患者群体的相当比例。

The FDA has assigned a Prescription Drug User Fee Act (PDUFA) target action date of October 24, 2026..

美国食品药品监督管理局（FDA）已根据《处方药用户付费法案》（PDUFA）将目标审批日期定为2026年10月24日。

We plan to submit a separate sNDA in the coming days, seeking approval for lower doses in patients weighing 13 - 27 kg.

我们计划在未来几天内提交一份单独的sNDA，寻求批准用于体重在13-27公斤患者的较低剂量。

Japan

日本

We expect to launch Joenja for the treatment of APDS in adult and pediatric patients aged 4 years and older in the third quarter of 2026.

我们预计将于2026年第三季度推出Joenja，用于治疗4岁及以上成人和儿科患者的APDS。

European Economic Area (EEA)

欧洲经济区（EEA）

On May 22, 2026, we announced that the European Commission (EC) had granted Marketing Authorization for Joenja as the first and only approved treatment of APDS in adult and pediatric patients 12 years of age and older. Joenja was commercially launched in Germany on July 1, 2026, marking the first European launch following EC approval, with additional launches anticipated pending completion of national reimbursement negotiations..

2026年5月22日，我们宣布欧盟委员会（EC）已授予Joenja上市许可，使其成为首个且唯一获批用于治疗12岁及以上成人和儿科患者活化磷酸肌醇3-激酶δ综合征（APDS）的药物。Joenja于2026年7月1日在德国正式商业化上市，标志着获得欧盟委员会批准后的首次欧洲上市，随着各国医保报销谈判的完成，预计还将有更多国家陆续上市。

Other countries

其他国家

On July 8, 2026, Joenja was approved by Health Canada for the treatment of APDS in adult and pediatric patients 12 years of age and older.

2026年7月8日，Joenja获得加拿大卫生部批准，用于治疗12岁及以上成人和儿童患者的活化磷酸肌醇3-激酶δ综合征（APDS）。

On July 10, 2026, Joenja was approved by the South Korea Ministry of Food and Drug Safety for the treatment of APDS in adult and pediatric patients 12 years of age and older.

2026年7月10日，Joenja获得韩国食品医药品安全部批准，用于治疗12岁及以上成人和儿科患者的活化磷酸肌醇3-激酶δ综合征（APDS）。

Leniolisib for additional primary immunodeficiencies (PIDs)

Leniolisib 用于其他原发性免疫缺陷病（PIDs）

Two Phase II clinical trials are evaluating leniolisib for additional primary immunodeficiencies (PIDs) with immune dysregulation, including genetically identifiable PIDs linked to altered PI3Kδ signaling and common variable immunodeficiency or CVID, which represent substantially larger patient populations than APDS.

两项II期临床试验正在评估leniolisib在伴有免疫失调的其他原发性免疫缺陷病（PIDs）中的疗效，包括与PI3Kδ信号通路改变相关的可基因鉴定的PIDs以及常见变异型免疫缺陷病（CVID），这些疾病所代表的患者群体规模远大于APDS。

Patient enrollment in both clinical trials is complete and we anticipate trial read-outs in the fourth quarter of 2026, consistent with prior guidance. The PI3Kδ pathway is seen as a key driver of immune dysregulation in many PIDs, and we currently anticipate conducting a single registrational Phase III trial in the broader CVID indication, incorporating patient populations from both studies..

两项临床试验的患者入组工作均已完成，我们预计将于2026年第四季度公布试验结果，与此前指引一致。PI3Kδ通路被视为许多原发性免疫缺陷病（PID）中免疫失调的关键驱动因素，我们目前计划在更广泛的常见变异型免疫缺陷病（CVID）适应症中开展一项单一的注册性III期临床试验，将两项研究中的患者人群纳入其中。

A presentation at the 2026 Annual Meeting of the Clinical Immunology Society (CIS), which took place May 6-9, included clinician expanded access experience with leniolisib to treat immune dysregulation in patients with CVID and CVID-like disorders. Clinician-reported outcomes demonstrated improvements, with no progression, in clinical manifestations of immune dysregulation as well as improvements in patients’ quality of life..

在2026年5月6日至9日举行的临床免疫学会（CIS）年会上，一项报告介绍了医生通过扩大使用途径应用leniolisib治疗常见变异型免疫缺陷病（CVID）及CVID样疾病患者免疫失调的临床经验。医生报告的结果显示，患者的免疫失调临床表现得到改善且无进展，同时患者的生活质量也有所提高。

Other events

其他事件

As we continue to improve operating efficiency in line with our strategy, we have decided to close our production-support site in Évry, France, with the closure expected to take effect in the fourth quarter of 2026. As a result, we recognized a one-time charge in the current quarter to reflect the estimated costs associated with the planned closure..

随着我们继续按照战略提高运营效率，我们已决定关闭位于法国埃夫里的生产支持站点，预计该关闭将于2026年第四季度生效。因此，我们在本季度确认了一次性费用，以反映与计划关闭相关的估计成本。

Financial Summary

财务摘要

Consolidated Statement of Income

合并利润表

2Q 2026

2026年第二季度

2Q 2025

2025年第二季度

1H 2026

2026年上半年

1H 2025

2025年上半年

Amounts in US$m except per share data

金额单位为百万美元，每股数据除外

Total Revenues

总收入

90.2

93.2

162.7

172.3

Cost of sales

销售成本

(14.5)

(9.0)

（9.0）

(21.2)

(17.3)

Gross profit

毛利

75.7

84.2

141.5

155.0

Other income

其他收入

1.4

1.8

2.2

Research and development

研发

(32.3)

(23.7)

(57.8)

(44.8)

General and administrative

一般及行政费用

(14.9)

（14.9）

(20.5)

(30.2)

(43.0)

Marketing and sales

市场营销与销售

(28.6)

(31.0)

(58.9)

(65.6)

Other Operating Costs

其他运营成本

(75.8)

(75.2)

(146.9)

(153.4)

Operating profit (loss)

营业利润（亏损）

1.3

10.8

(3.6)

3.8

Finance result (net) and share of result in associates

财务业绩（净额）及在联营企业中的损益份额

1.8

(3.7)

1.9

(8.5)

Profit (loss) before tax

税前利润（亏损）

3.0

7.1

(1.7)

(4.7)

Income tax credit (expense)

所得税抵免（费用）

(1.4)

(2.5)

(1.9)

(5.6)

Profit (loss) for the period

本期利润（亏损）

1.6

4.6

(3.6)

(10.3)

Earnings per share

每股收益

Basic, attributable to equity holders of the parent (US$)

基本每股收益，归属于母公司股东（美元）

0.003

0.007

(0.005)

(0.015)

Diluted, attributable to equity holders of the parent (US$)

稀释后，归属于母公司股东的每股收益（美元）

0.002

0.006

(0.005)

(0.015)

Segment information - Revenues

分部信息 - 收入

2Q 2026

2026年第二季度

2Q 2025

2025年第二季度

1H 2026

2026年上半年

1H 2025

2025年上半年

Amounts in US$m

金额（单位：百万美元）

Revenue - RUCONEST (US)

收入 - RUCONEST（美国）

72.0

79.6

130.2

146.2

Revenue - RUCONEST (EU and RoW)

收入 - RUCONEST（欧盟及世界其他地区）

0.3

0.8

0.4

2.8

Total Revenues - RUCONEST

总收入 - RUCONEST

72.3

80.4

130.7

149.0

Revenue - Joenja (US)

收入 - Joenja（美国）

15.4

11.8

26.9

21.3

二十一又十分之三

Revenue - Joenja (EU and RoW)

收入 - Joenja（欧盟及世界其他地区）

2.5

1.0

5.1

2.0

Total Revenues - Joenja

总收入 - Joenja

17.9

12.8

32.0

23.3

Total Revenues - US

总收入 - 美国

87.4

91.4

157.1

167.5

Total Revenues - EU and RoW

总收入 - 欧盟及世界其他地区

2.8

1.8

5.5

4.8

Total Revenues

总收入

90.2

93.2

162.7

172.3

Consolidated Balance Sheet

合并资产负债表

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Amounts in US$m

金额（单位：百万美元）

Cash and cash equivalents, restricted cash and marketable securities

现金及现金等价物、受限现金和有价证券

159.5

181.1

Current assets

流动资产

280.7

299.5

Total assets

总资产

468.0

500.0

五百点零

Current liabilities

流动负债

93.2

115.8

Shareholders' equity

股东权益

270.5

277.1

Figures may not add up due to rounding.

由于四舍五入，各项数字之和可能与总数不符。

Financial highlights

财务亮点

Second quarter 2026

2026年第二季度

For the second quarter of 2026, total revenues decreased by US$3.0 million, or 3%, to US$90.2 million, compared to US$93.2 million in the second quarter of 2025. RUCONEST revenues amounted to US$72.3 million, a 10% decrease compared to the second quarter of 2025. The decrease in RUCONEST® revenues was primarily driven by a decrease in volume.

2026年第二季度，总收入为9,020万美元，较2025年第二季度的9,320万美元减少300万美元，降幅为3%。RUCONEST收入为7,230万美元，较2025年第二季度下降10%。RUCONEST®收入的下降主要源于销量的减少。

Joenja revenues amounted to US$17.9 million in the second quarter of 2026, a 40% increase compared to the second quarter of 2025. This increase in Joenja revenues was primarily driven by an increase in volume..

2026年第二季度，Joenja的营收达到1,790万美元，较2025年第二季度增长40%。Joenja营收的增长主要得益于销量的提升。

Gross profit decreased by US$8.5 million, or 10%, to US$75.7 million, compared to US$84.2 million in the second quarter of 2025, mainly due to manufacturing-related impairments of inventory (US$4.9 million) and the decrease in revenues.

毛利润减少了850万美元，即10%，降至7,570万美元，而2025年第二季度为8,420万美元，主要原因是与制造相关的存货减值（490万美元）以及收入下降。

The operating profit amounted to US$1.3 million compared to US$10.8 million in the second quarter of 2025. Excluding US$4.9 million in one-time manufacturing-related impairments of inventory and US$1.7 million in expenses associated with the planned closure of the production-support site in Évry, France, adjusted operating profit.

营业利润为130万美元，而2025年第二季度为1,080万美元。若排除与库存相关的一次性制造减值损失490万美元，以及与计划关闭法国埃夫里生产支持站点相关的费用170万美元，调整后营业利润。

in the second quarter 2026 amounted to US$7.9 million. Excluding US$2.1 million of non-recurring Abliva acquisition-related expenses, adjusted operating profit in the second quarter 2025 amounted to US$12.9 million. The operating result was primarily impacted by manufacturing-related impairments of inventory and a decrease in revenues, while operating expenses remained similar to the second quarter of 2025..

2026年第二季度的营业利润为790万美元。剔除与收购Abliva相关的210万美元非经常性费用后，2025年第二季度的调整后营业利润为1290万美元。营业业绩主要受到存货减值（与生产相关）和收入下降的影响，而运营费用与2025年第二季度基本持平。

The finance result (net) and share of result in associates amounted to a gain of US$1.8 million compared to a loss of US$3.7 million in the second quarter of 2025. This improvement was mainly driven by favorable EUR/USD exchange rate movements, resulting in a foreign currency gain of US$2.9 million in 2026, compared to a loss of US$1.9 million in the second quarter of 2025..

财务业绩（净额）及联营公司损益份额为收益180万美元，而2025年第二季度为亏损370万美元。这一改善主要得益于欧元/美元汇率的有利变动，导致2026年实现汇兑收益290万美元，而2025年第二季度则为汇兑损失190万美元。

The Company had a net profit of US$1.6 million, compared to US$4.6 million in the second quarter of 2025. The effect of the aforementioned drivers was partially offset by a favorable change in the net finance result.

公司净利润为160万美元，而2025年第二季度为460万美元。上述驱动因素的影响被净财务结果的有利变化部分抵消。

Cash used in operations amounted to US$9.7 million, compared to US$11.7 million cash generated from operations in the second quarter of 2025. Cash and cash equivalents, restricted cash and marketable securities decreased from US$171.8 million at the end of first quarter of 2026 to US$159.5 million at the end of the second quarter of 2026, primarily driven by unfavorable working capital movements, mainly a decrease in trade and other payables and an increase in inventories, as well as income tax payments, partially offset by collections of trade and other receivables..

运营活动使用的现金为970万美元，而2025年第二季度运营活动产生的现金为1,170万美元。现金及现金等价物、受限现金和可流通证券从2026年第一季度末的1.718亿美元减少至2026年第二季度末的1.595亿美元，主要受营运资本不利变动的影响，主要是应付账款和其他应付款项减少以及存货增加，同时还有所得税支付的影响，但部分被应收账款和其他应收款项的收回所抵消。

Adjusted Operating Profit is a non-IFRS measure used by management to assess underlying operating performance and provides additional insight into the Company's core operating profitability. It excludes certain non-core items.

经调整经营利润是一项非国际财务报告准则（IFRS）指标，管理层使用该指标评估基础经营业绩，并进一步洞察公司的核心经营盈利能力。该指标剔除了某些非核心项目。

First half year 2026

2026年上半年

Total revenues decreased 6% during the first half of 2026 to US$162.7 million, compared to US$172.3 million during the first half of 2025. For the first half of 2026, total RUCONEST revenues were 12% lower at US$130.7 million, compared to revenues of US$149.0 million for the first half of 2025. The decrease in RUCONEST revenues was primarily driven by a decrease in volume.

2026年上半年，总收入同比下降6%，至1.627亿美元，而2025年上半年为1.723亿美元。2026年上半年，RUCONEST总收入为1.307亿美元，较2025年上半年的1.490亿美元下降12%。RUCONEST收入下降的主要原因是销量减少。

。

Joenja revenues amounted to US$32.0 million in the first half of 2026, a 37% increase compared to the first half of 2025. This increase in Joenja revenues was primarily driven by an increase in volume.

2026年上半年，Joenja的收入达到3,200万美元，较2025年上半年增长37%。Joenja收入的增长主要得益于销量的增加。

Gross profit decreased by US$13.5 million, or 9%, to US$141.5 million, compared to US$155.0 million in the first half of 2025, mainly due to the decrease in revenues and manufacturing-related impairments of inventory (US$4.9 million). Further details on revenue and gross profit segmentation is provided in .

毛利润减少1,350万美元（即9%），至1.415亿美元，而2025年上半年为1.55亿美元，主要原因是收入下降以及与制造相关的存货减值（490万美元）。关于收入和毛利润细分的更多详情见。

Note 7. Segment informat

附注7. 分部信息

ion

离子

in the Notes to the condensed consolidated interim financial statements of this press release.

在本新闻稿的简明合并中期财务报表附注中。

The operating loss amounted to US$3.6 million compared to an operating profit of US$3.8 million in the first half of 2025. Excluding US$4.9 million in one-time manufacturing-related impairments of inventory and US$1.7 million in expenses associated with the planned closure of the production-support site in Évry, France, adjusted operating profit in the first half 2026 amounted to US$3.0 million.

营业亏损为360万美元，而2025年上半年营业利润为380万美元。若剔除与存货相关的一次性制造减值490万美元，以及与计划关闭法国埃夫里生产支持站点相关的费用170万美元，2026年上半年的调整后营业利润为300万美元。

Excluding US$9.9 million of non-recurring Abliva acquisition-related expenses, adjusted operating profit in the first half 2025 amounted to US$13.7 million. The deteriorated operating result was primarily driven by a decrease in revenues and manufacturing-related impairments of inventories in 2026..

在剔除990万美元的一次性Abliva收购相关费用后，2025年上半年的调整后营业利润为1,370万美元。经营业绩恶化主要归因于收入下降以及2026年与生产相关的存货减值。

The finance result (net) and share result in associates amounted to a gain of US$1.9 million compared to a loss of US$8.5 million in the first half of 2025. This improvement was mainly driven by favorable EUR/USD exchange rate movements, resulting in a foreign currency gain of US$5.3 million in the first half year of 2026, compared to a loss of US$4.5 million in the first half year of 2025..

财务净结果及联营公司损益合计为收益190万美元，而2025年上半年为亏损850万美元。这一改善主要得益于欧元/美元汇率的有利变动，使得2026年上半年实现汇兑收益530万美元，而2025年上半年则为汇兑损失450万美元。

The Company had a net loss of US$3.6 million, compared to a net loss of US$10.3 million in the first half of 2025. In addition to the aforementioned drivers, the net result was positively impacted by a lower tax expense of US$1.9 million compared to US$5.6 million in the first half of 2025.

公司净亏损为360万美元，而2025年上半年的净亏损为1,030万美元。除上述驱动因素外，所得税费用从2025年上半年的560万美元降至190万美元，对净利润产生了正面影响。

Cash used in operations amounted to US$7.7 million, compared to US$12.0 million of cash generated from operations in the first half of 2025. Cash and cash equivalents, restricted cash and marketable securities decreased by US$21.6 million to US$159.5 million from US$181.1 million at the end of 2025, primarily driven by negative working capital movements, increased income tax payments and US$12.3 million settlement of the lease liability following the early termination of the DSP facility lease at Pivot Park in Oss, the Netherlands..

经营所用现金为770万美元，而2025年上半年经营活动产生的现金为1,200万美元。现金及现金等价物、受限现金和有价证券从2025年底的1.811亿美元减少2,160万美元至1.595亿美元，主要受营运资本负面变动、所得税支付增加以及因提前终止位于荷兰奥斯的Pivot Park的DSP设施租赁而结算1,230万美元租赁负债的影响。

Outlook/Summary

展望/摘要

For 2026, the Company anticipates:

2026年，公司预计：

Total revenues between US$375.0 million and US$395.0 million (0% to 5% growth), updated to reflect a US$30 million reduction compared with prior guidance.

总收入介于3.75亿美元至3.95亿美元之间（增长率为0%至5%），已更新以反映较此前指引下调3,000万美元。

Total operating expenses between US$315.0 million and US$320.0 million (1% to 3% growth), including over US$40 million incremental R&D investment to advance the pipeline and US$9 million structural G&A cost reductions based on the plan announced in October 2025, reflecting an improvement of US$15 million from prior guidance..

总运营支出介于3.15亿美元至3.20亿美元之间（增长1%至3%），其中包括为推动产品管线进展而增加的逾4,000万美元研发投资，以及根据2025年10月宣布的计划实现的900万美元结构性一般及行政费用削减，较此前指引改善1,500万美元。

RUCONEST revenue stabilization and return to growth during second half of 2026, and significant and accelerating annual Joenja U.S. and ex-U.S. growth.

RUCONEST在2026年下半年实现收入稳定并恢复增长，同时Joenja在美国及美国以外地区的年度增长显著且不断加速。

Additional regulatory approvals and commercial launches for leniolisib for APDS patients 12 years of age or older and for pediatric label expansion in key global markets.

在关键全球市场，针对12岁及以上活化磷脂酰肌醇3-激酶δ综合征（APDS）患者的leniolisib额外监管审批和商业化发布，以及儿科适应症的标签扩展。

Top-line data readouts for the two ongoing leniolisib Phase II clinical trials in PIDs with immune dysregulation, including CVID, to expand the asset’s addressable patient population.

针对两项正在进行的leniolisib治疗免疫失调原发性免疫缺陷病（包括常见变异型免疫缺陷病）的II期临床试验的顶线数据读出，旨在扩大该药物的适用患者人群。

Completion of enrollment in the pivotal FALCON clinical study for napazimone (KL1333) in mitochondrial DNA-driven primary mitochondrial diseases.

完成napazimone（KL1333）在由线粒体DNA驱动的原发性线粒体疾病中的关键性FALCON临床研究的入组。

Enhancing capital efficiency to drive growth and build a leading global rare disease company.

提升资本效率，驱动增长，打造全球领先的罕见病企业。

Continued focus on potential acquisitions and in-licensing of clinical stage opportunities in rare diseases. Financing, if required, would come via a combination of our strong balance sheet and access to capital markets.

持续聚焦于罕见病领域临床阶段项目的潜在收购与许可引进。如需融资，我们将凭借强劲的资产负债表及资本市场渠道相结合的方式进行。

No further specific financial guidance for 2026 is provided.

未提供2026年进一步的具体财务指引。

Trademarks

商标

Joenja® and RUCONEST® are registered trademarks owned by or licensed to Pharming Group N.V. or its affiliates.

Joenja® 和 RUCONEST® 是 Pharming Group N.V. 或其关联公司拥有或获许可使用的注册商标。

Additional information

附加信息

Presentation

演示

The conference call presentation is available on the Pharming.com website from 07:30 CEST today.

电话会议演示文稿自今日中欧夏令时 07:30 起可在 Pharming.com 网站上获取。

Conference Call

电话会议

The conference call will begin at 13:30 CEST/07:30 EDT on Thursday, July 30. A transcript will be made available on the Pharming.com website in the days following the call.

电话会议将于7月30日（星期四）13:30 CEST/07:30 EDT开始。会议记录将在电话会议结束后的几天内发布在Pharming.com网站上。

Please note, the Company will only take questions from dial-in attendees.

请注意，公司仅接受通过电话接入的参会者提问。

Webcast Link:

网络直播链接：

https://edge.media-server.com/mmc/p/m35zejc7

Conference call dial-in details:

电话会议拨入详情：

https://register-conf.media-server.com/register/BId285845cff504c39931913d279f646ea

Additional information on how to register for the conference call/webcast can be found on the

有关如何注册电话会议/网络直播的更多信息，请参见

Pharming.com website.

Pharming.com 网站。

Financial Calendar 2026

2026年财务日历

3Q 2026 financial results November 5, 2026

2026年第三季度财务业绩 2026年11月5日

For further public information, contact:

如需更多公开信息，请联系：

Pharming

网络钓鱼

Michael Levitan, VP Investor Relations and Capital Markets

迈克尔·莱维坦，投资者关系与资本市场副总裁

T: +1 (908) 705 1696

电话：+1 (908) 705 1696

东：

investor@pharming.com

Saskia Mehring, Head of Corporate Communications

萨斯基亚·梅林，企业传播主管

T: +31 6 28 32 60 41

电话：+31 6 28 32 60 41

东：

media.relations@pharming.com

Media Relations

媒体关系

Julia Deutsch (Lyra Strategic Advisory on behalf of Pharming)

朱莉娅·多伊奇（代表法明公司的莱拉战略咨询）

东：

JDeutsch@lyraadvisory.com

Netherlands: Leon Melens (LifeSpring Life Sciences Communication on behalf of Pharming)

荷兰：Leon Melens（LifeSpring 生命科学传播公司，代表 Pharming）

T: +31 6 53 81 64 27

电话：+31 6 53 81 64 27

About Pharming Group N.V.

关于 Pharming Group N.V.

Pharming Group N.V. (Euronext Amsterdam: PHARM/Nasdaq: PHAR) is a global biopharmaceutical company dedicated to transforming the lives of patients with rare, debilitating, and life-threatening diseases. We develop and commercialize innovative medicines, including small molecules and biologics. Pharming is headquartered in Leiden, the Netherlands, with U.S.

Pharming Group N.V.（泛欧交易所阿姆斯特丹：PHARM/纳斯达克：PHAR）是一家全球性生物制药公司，致力于改善患有罕见、致残及危及生命疾病的患者的生活。我们开发并商业化创新药物，包括小分子药物和生物制品。Pharming 总部位于荷兰莱顿，在美国设有业务。

and European operations..

以及欧洲业务。

For more information, visit

更多信息，请访问

www.pharming.com

and find us on

并在以下平台找到我们

领英

。

Auditor’s involvement

审计师的参与

The Condensed Consolidated Interim Financial Statements have not been audited by the Company’s statutory auditor.

简明合并中期财务报表未经公司法定审计师审计。

Responsibility Statement

责任声明

The Board of Directors of the Company (the “Board”) hereby declares that to the best of its knowledge, the condensed consolidated interim financial statements, which have been prepared in accordance with IAS 34 (interim financial reporting), give a true and fair view of the assets, liabilities, financial position and profit or loss of the Company, and this interim Board report includes a fair review of the information required pursuant to section 5:25d(8) and (9) of the Dutch Financial Supervision Act (Wet op het financieel toezicht).

本公司董事会（“董事会”）谨此声明，据其所知，按照《国际会计准则第34号——中期财务报告》编制的简明合并中期财务报表真实、公允地反映了本公司的资产、负债、财务状况及损益情况；且本中期董事会报告包含了对根据《荷兰金融监管法》（Wet op het financieel toezicht）第5:25d条第(8)款和第(9)款规定所需信息的公允审阅。

。

Leiden, July 30, 2026

莱顿，2026年7月30日

Fabrice Chouraqui, Chief Executive Officer and Executive Director

法布里斯·肖拉基，首席执行官兼执行董事

Richard Peters, Non-Executive Director and Chairman of the Board of Directors

理查德·彼得斯，非执行董事兼董事会主席

Mark Pykett, Non-Executive Director

马克·皮凯特，非执行董事

Barbara Yanni, Non-Executive Director

芭芭拉·雅尼，非执行董事

Leonard Kruimer, Non-Executive Director

伦纳德·克鲁伊默，非执行董事

Jabine van der Meijs, Non-Executive Director

贾宾·范德梅斯，非执行董事

Elaine Sullivan, Non-Executive Director

伊莱恩·沙利文，非执行董事

Forward-looking Statements

前瞻性陈述

This press release may contain forward-looking statements. Forward-looking statements are statements of future expectations that are based on management’s current expectations and assumptions and involve known and unknown risks and uncertainties that could cause actual results, performance, or events to differ materially from those expressed or implied in these statements.

本新闻稿可能包含前瞻性陈述。前瞻性陈述是关于未来预期的陈述，基于管理层当前的预期和假设，并涉及已知和未知的风险与不确定性，这些风险与不确定性可能导致实际结果、业绩或事件与这些陈述中明示或暗示的内容存在重大差异。

These forward-looking statements are identified by their use of terms and phrases such as “aim”, “ambition”, ‘‘anticipate’’, ‘‘believe’’, ‘‘could’’, ‘‘estimate’’, ‘‘expect’’, ‘‘goals’’, ‘‘intend’’, ‘‘may’’, “milestones”, ‘‘objectives’’, ‘‘outlook’’, ‘‘plan’’, ‘‘probably’’, ‘‘project’’, ‘‘risks’’, “schedule”, ‘‘seek’’, ‘‘should’’, ‘‘target’’, ‘‘will’’ and similar terms and phrases.

这些前瞻性陈述通过使用诸如“目标”、“雄心”、“预期”、“相信”、“可能”、“估计”、“期望”、“目的”、“打算”、“可以”、“里程碑”、“指标”、“展望”、“计划”、“或许”、“预测”、“风险”、“时间表”、“寻求”、“应当”、“靶点”、“将会”等词语和短语以及类似表述来识别。

Examples of forward-looking statements may include statements with respect to timing and progress of Pharming's preclinical studies and clinical trials of its product candidates, Pharming's clinical and commercial prospects, and Pharming's expectations regarding its projected working capital requirements and cash resources, which statements are subject to a number of risks, uncertainties and assumptions, including, but not limited to the scope, progress and expansion of Pharming's clinical trials and ramifications for the cost thereof; and clinical, scientific, regulatory, commercial, competitive and technical developments.

前瞻性陈述的示例可能包括有关Pharming公司候选产品临床前研究和临床试验的时间安排和进展的陈述、Pharming公司的临床和商业前景，以及Pharming公司对其预计营运资金需求和现金资源的预期。这些陈述受多种风险、不确定性和假设的影响，包括但不限于Pharming公司临床试验的范围、进展和扩展及其对成本的影响；以及临床、科学、监管、商业、竞争和技术发展等方面的因素。

In light of these risks and uncertainties, and other risks and uncertainties that are described in Pharming's.

鉴于这些风险与不确定性，以及Pharming公司所描述的其他风险与不确定性。

2025

2025年

Annual Report and the Annual Report on Form 20-F for the year ended December 31,

截至12月31日年度的年度报告及20-F表格年度报告

2025,

2025年，

filed with the U.S. Securities and Exchange Commission, the events and circumstances discussed in such forward-looking statements may not occur, and Pharming's actual results could differ materially and adversely from those anticipated or implied thereby. All forward-looking statements contained in this press release are expressly qualified in their entirety by the cautionary statements contained or referred to in this section.

已向美国证券交易委员会备案，此类前瞻性陈述中讨论的事件和情况可能不会发生，Pharming 的实际结果可能与由此预期或暗示的结果存在重大且不利的差异。本新闻稿中包含的所有前瞻性陈述均受本节所载或提及的警示性陈述的明确限定，其全部内容由这些警示性陈述予以限定。

Readers should not place undue reliance on forward-looking statements. Any forward-looking statements speak only as of the date of this press release and are based on information available to Pharming as of the date of this release. Pharming does not undertake any obligation to publicly update or revise any forward-looking statement as a result of new information, future events or other information..

读者不应过度依赖前瞻性陈述。任何前瞻性陈述仅反映本新闻稿发布之日的情况，并基于Pharming在该日期可获得的信息。Pharming不承担因新信息、未来事件或其他信息而公开更新或修订任何前瞻性陈述的义务。

Inside Information

内幕信息

This press release relates to the disclosure of information that qualifies, or may have qualified, as inside information within the meaning of Article 7(1) of the EU Market Abuse Regulation.

本新闻稿涉及披露根据《欧盟市场滥用条例》第7(1)条的定义，构成或可能构成内幕信息的信息。

Pharming Group N.V.

法明集团 N.V.

Condensed Consolidated Interim Financial Statements in US Dollars (unaudited)

美元简明合并中期财务报表（未经审计）

For the period ended June 30, 2026

截至2026年6月30日止期间

Condensed consolidated interim statement of income

简明合并中期利润表

Condensed consolidated interim statement of comprehensive income

简明合并中期综合收益表

Condensed consolidated interim balance sheet

简明合并中期资产负债表

Condensed consolidated interim statement of changes in equity

简明合并中期权益变动表

Condensed consolidated interim statement of cash flow

简明合并中期现金流量表

CONDENSED CONSOLIDATED INTERIM STATEMENT OF INCOME (UNAUDITED)

简明合并中期利润表（未经审计）

For the period ended June 30

截至6月30日的期间

Amounts in US$ ‘000

金额（千美元）

notes

笔记

1H 2026

2026年上半年

1H 2025

2025年上半年

Revenues

收入

162,660

172,315

Costs of sales

销售成本

九

(21,189)

(17,295)

Gross profit

毛利润

141,471

155,020

Other income

其他收入

1,801

2,232

Research and development

研发

(57,819)

(44,837)

General and administrative

一般及行政

(30,165)

(42,991)

Marketing and sales

营销与销售

(58,886)

(65,619)

Other Operating Costs

其他运营成本

(146,870)

(153,447)

Operating profit (loss)

营业利润（亏损）

(3,598)

3,805

Other finance income

其他财务收入

7,119

1,263

Other finance expenses

其他财务费用

(5,403)

(9,785)

Finance result, net

财务结果，净额

1,716

(8,522)

Share of net profits (loss) in associates using the equity method

采用权益法核算的联营企业净利润（亏损）份额

十二

168

一百六十八

Profit (loss) before tax

税前利润（亏损）

(1,714)

(4,709)

Income tax credit (expense)

所得税抵免（费用）

十一

(1,861)

(5,629)

Profit (loss) for the period

本期利润（亏损）

(3,575)

(10,338)

Attributable to:

归因于：

Equity holders of the parent

母公司股东

(3,575)

(10,025)

Non-controlling interests

非控制性权益

—

(313)

Earnings per share

每股收益

Basic earnings per share (US$)

基本每股收益（美元）

十八

(0.005)

(0.015)

Diluted earnings per share (US$)

稀释每股收益（美元）

十八

(0.005)

(0.015)

CONDENSED CONSOLIDATED INTERIM STATEMENT OF COMPREHENSIVE INCOME (UNAUDITED)

简明合并中期综合收益表（未经审计）

For the period ended June 30

截至6月30日的期间

Amounts in US$ ‘000

金额（千美元）

1H 2026

2026年上半年

1H 2025

2025年上半年

Profit (loss) for the period

本期利润（亏损）

(3,575)

(10,338)

Currency translation differences

货币折算差异

(8,433)

26,148

Items that may be subsequently reclassified to profit or loss

可能随后重分类至损益的项目

(8,433)

26,148

Other comprehensive income (loss), net of tax

其他综合收益（损失），税后净额

(8,433)

26,148

Total comprehensive income (loss) for the period

本期综合收益（亏损）总额

(12,008)

15,810

Attributable to:

归因于：

Equity holders of the parent

母公司股东

(12,008)

16,123

Non-controlling interests

非控制性权益

—

(313)

CONDENSED CONSOLIDATED INTERIM BALANCE SHEET (UNAUDITED)

简明合并中期资产负债表（未经审计）

Amounts in US$ ‘000

金额（千美元）

notes

笔记

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Non-current assets

非流动资产

Intangible assets

无形资产

128,082

135,538

Property, plant and equipment

物业、厂房及设备

6,425

7,233

Right-of-use assets

使用权资产

14,058

16,738

Long-term prepayments

长期预付款项

九十二

九十四

Deferred tax assets

递延所得税资产

28,838

31,017

三万一千零一十七

Investment accounted for using the equity method

采用权益法核算的投资

2,055

1,944

Investment in debt instruments designated as at FVTPL

指定为以公允价值计量且其变动计入当期损益的债务工具投资

6,520

6,703

Restricted cash

受限现金

1,225

一千二百二十五

1,227

Total non-current assets

非流动资产总额

187,295

200,495

Current assets

流动资产

Inventories

存货

十四

65,428

64,902

Trade and other receivables

贸易及其他应收款项

56,980

54,704

Restricted cash

受限现金

—

761

Marketable securities

有价证券

—

33,796

Cash and cash equivalents

现金及现金等价物

158,281

145,305

Total current assets

流动资产总额

280,689

299,469

Total assets

总资产

467,984

499,963

Equity

股权

Share capital

股本

8,081

8,009

Share premium

股本溢价

520,312

513,257

Other reserves

其他储备

20,342

28,819

Accumulated deficit

累计亏损

(278,245)

(272,983)

Total equity

股东权益总额

270,490

277,102

Non-current liabilities

非流动负债

Convertible bonds

可转换债券

92,401

九万两千四百零一

92,719

九万二千七百一十九

Lease liabilities

租赁负债

11,848

14,351

一万四千三百五十一

Total non-current liabilities

非流动负债总额

104,249

107,070

Current liabilities

流动负债

Convertible bonds

可转换债券

十七

5,469

5,336

Provisions

条款

1,878

1,187

Trade and other payables

贸易及其他应付款项

82,321

105,899

Lease liabilities

租赁负债

3,577

3,369

Total current liabilities

流动负债总额

93,245

115,791

Total equity and liabilities

权益和负债总额

467,984

499,963

CONDENSED CONSOLIDATED INTERIM STATEMENT OF CHANGES IN EQUITY (UNAUDITED)

简明合并中期权益变动表（未经审计）

For the period ended June 30

截至6月30日的期间

Attributable to equity holders of the parent

归属于母公司股东

Amounts in US$ ‘000

金额（千美元）

notes

笔记

Share capital

股本

Share premium

股本溢价

Other reserves

其他储备

Accumulated deficit

累计亏损

Subtotal

小计

Non-controlling interests

非控制性权益

Total equity

股东权益总额

Balance at January 1, 2025

2025年1月1日余额

7,769

488,990

(209)

(275,489)

221,061

—

221,061

Profit (loss) for the period

本期利润（亏损）

—

(10,025)

(313)

（313）

(10,338)

Other comprehensive income (loss) for the period

本期其他综合收益（损失）

—

26,148

—

26,148

—

26,148

Total comprehensive income (loss) for the period

本期综合收益（亏损）总额

—

26,148

(10,025)

16,123

(313)

15,810

Movement in reserves

准备金变动

十六

—

(31)

三十一

—

Income tax benefit from excess tax deductions related to share-based payments

与股份支付相关的超额税收扣除所产生的所得税收益

—

(209)

（209）

(209)

—

(209)

Share-based compensation

基于股份的薪酬

—

6,052

六千零五十二

—

6,052

Options exercised / LTIP shares issued

已行权期权 / 长期激励计划股份发行

五十二

2,863

—

(4,273)

(1,358)

—

(1,358)

Acquisition of a subsidiary

收购子公司

—

6,133

Acquisition of non-controlling interests

收购非控制性权益

—

(2,118)

(5,820)

(7,938)

Total transactions with owners, recognized directly in equity

与所有者进行的总交易，直接计入权益

五十二

2,863

(31)

(517)

（517）

2,367

313

三百一十三

2,680

Balance at June 30, 2025

截至2025年6月30日的余额

7,821

491,853

25,908

(286,031)

239,551

—

239,551

Balance at January 1, 2026

2026年1月1日余额

8,009

513,257

28,819

(272,983)

277,102

—

277,102

Profit (loss) for the period

本期利润（亏损）

—

(3,575)

—

(3,575)

Other comprehensive income (loss) for the period

当期其他综合收益（损失）

—

(8,433)

—

(8,433)

—

(8,433)

Total comprehensive income (loss) for the period

本期综合收益总额（亏损）

—

(8,433)

(3,575)

(12,008)

—

(12,008)

Movement in reserves

准备金变动

—

(44)

三十四

(10)

—

(10)

Income tax expense from excess tax deductions related to share-based payments

与股份支付相关的超额税收抵扣所产生的所得税费用

—

248

二百四十八

248

二百四十八

—

248

Share-based compensation

基于股份的薪酬

—

6,575

—

6,575

Options exercised / LTIP shares issued

行使期权 / 发行长期激励计划股份

7,056

—

(8,545)

(1,418)

—

(1,418)

Total transactions with owners, recognized directly in equity

与所有者之间的交易总额，直接计入权益

七十一

7,056

七千零五十六

(44)

(1,688)

5,395

—

5,395

Balance at June 30, 2026

截至2026年6月30日的余额

8,081

520,312

20,342

(278,245)

270,490

—

270,490

Comparative presentation updated for consistency.

比较列报已更新以保持一致性。

CONDENSED CONSOLIDATED INTERIM STATEMENT OF CASH FLOWS (UNAUDITED)

简明合并中期现金流量表（未经审计）

For the period ended June 30

截至6月30日的期间

Amounts in $’000

金额单位：千美元

1H 2026

2026年上半年

1H 2025

2025年上半年

Profit (loss) before tax

税前利润（亏损）

(1,714)

(4,709)

Adjustments to reconcile net profit (loss) to net cash used in operating activities:

将净利润（亏损）调节为经营活动产生的现金流量净额的调整项目：

Depreciation, amortization, impairment of non-current assets

折旧、摊销及非流动资产减值

6,154

5,284

Equity settled share based payments

以权益结算的股份支付

6,575

6,052

Loss (gain) on disposal of leases

租赁处置损益

三十八

(10)

（10）

Impairments of inventories²

存货减值²

5,990

3,742

Other finance income

其他财务收入

(7,119)

(1,263)

Other finance expenses

其他财务费用

5,371

9,650

Share of net losses (gains) in associates using the equity method

按权益法核算的联营企业净亏损（收益）份额

(168)

(8)

Operating cash flows before changes in working capital

营运资本变动前的经营现金流

15,127

18,738

Changes in working capital:

营运资本变动：

Inventories²

存货²

(7,256)

(4,051)

Trade and other receivables

贸易及其他应收款项

1,320

2,359

Payables and other current liabilities

应付账款及其他流动负债

(13,159)

1,031

Provisions

条款

691

六百九十一

—

Restricted cash

受限现金

709

(3,052)

Total changes in working capital

营运资本总变动

(17,695)

(3,713)

Interest received

收到的利息

1,266

1,273

Income taxes received (paid)

收到（支付）的所得税

(6,404)

(4,323)

Net cash flows generated from (used in) operating activities

经营活动产生的（用于）净现金流量

(7,706)

11,975

Capital expenditure for property, plant and equipment

物业、厂房及设备的资本支出

(321)

(410)

Investment intangible assets

投资性无形资产

—

(6)

Investment in associates using the equity method

采用权益法核算的联营企业投资

—

(429)

Purchases of marketable securities

有价证券的购买

(102,646)

—

Proceeds from sale of marketable securities

出售有价证券所得款项

18,124

84,967

Acquisition of a subsidiary, net of cash acquired

收购子公司，扣除所获现金

—

(57,476)

Net cash flows generated from (used in) investing activities

投资活动产生的（用于）净现金流量

(84,843)

26,646

Payment of lease liabilities

租赁负债的支付

(13,894)

(1,781)

Interests on lease liabilities

租赁负债利息

(242)

(562)

Interests on convertible bonds

可转换债券的利息

(2,630)

(2,450)

Exercise of share-based compensation awards

行使基于股份的薪酬奖励

5,098

1,287

Acquisition of non-controlling interests

收购非控股权益

—

(5,970)

Net cash flows generated from (used in) financing activities

筹资活动产生的（用于）现金流量净额

(11,668)

(9,476)

Increase (decrease) of cash

现金增加（减少）额

(104,217)

29,145

Exchange rate effects

汇率影响

(603)

8,002

Effect of reclassification of money market funds to cash equivalents (see note 15)

货币市场基金重分类为现金等价物的影响（见附注15）

117,796

—

Cash and cash equivalents at January 1

1月1日的现金及现金等价物

145,305

54,944

Total cash and cash equivalents at June 30

截至6月30日的现金及现金等价物总额

158,281

92,091

Notes to the condensed consolidated interim financial statements

简明合并中期财务报表附注

For the period ended June 30, 2026

截至2026年6月30日止期间

Company information

公司信息

Pharming Group N.V. is a limited liability public company which is listed on Euronext Amsterdam (PHARM) and on the NASDAQ (PHAR), with its headquarters and registered office located at:

Pharming Group N.V. 是一家有限责任公司，在阿姆斯特丹泛欧交易所（PHARM）和纳斯达克（PHAR）上市，其总部和注册办公地点位于：

Darwinweg 24

达尔文路24号

2333 CR Leiden

2333 CR 莱顿

The Netherlands

荷兰

Pharming Group N.V. is a global biotechnology company that develops and commercializes innovative therapies for rare and ultra-rare diseases with significant unmet need. We focus on immunological and genetic conditions where our scientific and commercial expertise can help advance care over the long term..

Pharming Group N.V. 是一家全球性生物技术公司，致力于开发并商业化创新疗法，以满足罕见病和超罕见病领域尚未被满足的重大医疗需求。我们专注于免疫学和遗传性疾病，凭借我们的科学与商业专长，推动长期护理水平的提升。

Statement of compliance

合规声明

The consolidated interim financial statements for the six-month period ended June 30, 2026, have been prepared in accordance with International Accounting Standard IAS 34, Interim financial reporting. The condensed consolidated interim financial statements should be read in conjunction with the annual financial statements for the year ended December 31, 2025.

截至2026年6月30日止六个月期间的合并中期财务报表已根据《国际会计准则第34号——中期财务报告》编制。简明合并中期财务报表应与截至2025年12月31日止年度的年度财务报表一并阅读。

They do not include all of the information required for a complete set of financial statements in accordance with IFRS Accounting Standards. However, selected explanatory notes are included to explain events and transactions that are significant to an understanding of the changes in the Group’s financial position and performance since the last annual financial statements..

这些报表并未包含根据《国际财务报告准则》（IFRS）编制完整财务报表所需的全部信息。然而，其中包含了部分选定的附注，以解释对于理解本集团自上一份年度财务报表以来财务状况和经营成果的变化具有重大影响的事项和交易。

These condensed consolidated interim financial statements were authorized for issue by the Board of Directors on July 29, 2026.

这些简明合并中期财务报表已于2026年7月29日经董事会批准发布。

The published figures in these condensed consolidated interim financial statements are unaudited.

这些简明合并中期财务报表中公布的数字未经审计。

Accounting policies

会计政策

Accounting policies are consistent with those of the financial statements for the year ended December 31, 2025. The following exchange rates have been applied:

会计政策与截至2025年12月31日止年度的财务报表所采用的会计政策保持一致。已应用以下汇率：

Applied exchange rates

适用汇率

June 30, 2026

2026年6月30日

Average 1H 2026

2026年上半年平均

December 31, 2025

2025年12月31日

Average 1H 2025

2025年上半年平均值

EUR/USD

欧元/美元

1.1394

1.1687

1.1713

1.0889

AUD/USD

澳元/美元

0.6887

0.7017

0.6699

0.6322

GBP/USD

英镑/美元

1.3221

1.3458

1.3455

1.2992

SEK/USD

瑞典克朗/美元

0.1027

0.1084

0.1083

0.0981

Estimates and judgements

估计与判断

The preparation of interim financial statements in conformity with IAS 34 and Book 2 Title 9 of the Dutch Civil Code requires the use of certain critical accounting estimates. It also requires management to exercise its judgement in the process of applying the Company’s accounting policies. In preparing these condensed consolidated interim financial statements, the significant judgements made by management in applying the Company’s accounting policies were the same as those applied to the consolidated financial statements for the year ended December 31, 2025..

根据《国际会计准则第34号》和《荷兰民法典》第二编第九标题的规定编制中期财务报表，需要使用某些关键的会计估计。此外，还要求管理层在应用公司会计政策的过程中行使判断力。在编制这些简明合并中期财务报表时，管理层在应用公司会计政策方面所作出的重大判断与应用于截至2025年12月31日止年度的合并财务报表中的判断一致。

Going concern

持续经营

In preparing and finishing the interim financial statements the Board of Directors of Pharming have assessed the Company’s ability to fund its operations for a period of at least twelve months after the date the interim financial statements are issued. Based upon the assessment on a going concern basis, the Company has concluded that funding of its operations for a period of twelve months, after the date the interim financial statements are issued, is realistic and achievable.

在编制和完成中期财务报表时，Pharming公司董事会已评估了公司自中期财务报表发布之日起至少十二个月内为其运营提供资金的能力。基于持续经营假设进行的评估，公司得出结论：自中期财务报表发布之日起十二个月内为其运营提供资金是现实且可实现的。

Overall, based on the outcome of this assessment, the interim financial statements have been prepared on a going concern basis..

总体而言，根据本次评估的结果，中期财务报表系以持续经营为基础编制。

Seasonality of operations

运营的季节性

Seasonality has no material impact on Company’s interim financial statements.

季节性因素对公司中期财务报表无重大影响。

Segment information

分部信息

Operating segments are components of the Company that engage in business activities from which it may incur expenses, for which discrete financial information is available and whose operating results are evaluated regularly by the Company’s Chief Operating Decision Maker (“CODM”) to make decisions about resources to be allocated to the segment and assess its performance.

经营分部是指公司内从事业务活动的组成部分，这些活动可能产生费用，且有独立的财务信息可供使用，公司的首席运营决策者（“CODM”）会定期评估其经营成果，以决定分配给该分部的资源并评估其绩效。

The Executive Members of the Board of Directors are considered the CODM..

董事会的执行成员被视为首席运营决策者（CODM）。

CODM reviews the Company’s results under four operating segments based on a combination of the products that the Company has launched - RUCONEST and Joenja, and the main geographies where sales are consummated - focused on the US and reporting, in aggregate, EU and Rest of the World (“RoW”). The four operating segments correspond to each of its four reportable segments for financial reporting purposes..

首席运营决策者根据公司已推出的产品（RUCONEST 和 Joenja）以及销售完成的主要地理区域（聚焦于美国，并将欧盟和世界其他地区（“RoW”）合并列报）的组合，对公司的业绩按四个经营分部进行审查。这四个经营分部分别对应其用于财务报告目的的四个报告分部。

The CODM reviews revenues and gross profit to assess the performance of their operating segments, which are the sole performance measures on segment level which are provided regularly to the CODM. No other information, such as operating expenses, assets or other performance indicators on segment level are provided regularly to the CODM.

首席运营决策者（CODM）通过审查收入和毛利来评估其经营分部的业绩，这些是定期向首席运营决策者提供的唯一分部层面业绩指标。其他信息，如分部层面的运营费用、资产或其他业绩指标，并不定期向首席运营决策者提供。

。

Total revenues and gross profit per each operating and reportable segment for the period ended June 30 are:

截至6月30日止期间，各经营及可报告分部的总收入和毛利如下：

Amounts in US$ ‘000

金额（千美元）

1H 2026

2026年上半年

1H 2025

2025年上半年

RUCONEST

Joenja

乔恩贾

Total

总计

RUCONEST

Joenja

乔恩贾

Total

总计

Revenues:

收入：

美国

130,225

26,944

157,169

146,244

21,272

167,516

EU and RoW

欧盟与世界其他地区

439

四百三十九

5,052

5,491

2,759

2,040

4,799

Total revenues

总收入

130,664

31,996

162,660

149,003

23,312

172,315

Gross profit:

毛利润：

美国

112,971

23,472

136,443

134,211

18,448

152,659

EU and RoW

欧盟及世界其他地区

176

4,852

5,028

340

三百四十

2,021

2,361

Total gross profit

毛利总额

113,147

28,324

141,471

134,551

20,469

155,020

There are no intersegment sales.

不存在分部间销售。

Other income

其他收入

Other income decreased by US$0.4 million in the first half of 2026 to US$1.8 million as compared to US$2.2 million the first half of 2025.

2026年上半年，其他收入为180万美元，较2025年上半年的220万美元减少40万美元。

Expenses by nature

按性质分类的费用

Costs of sales

销售成本

Amounts in US$ ‘000

金额（单位：千美元）

1H 2026

2026年上半年

1H 2025

2025年上半年

Cost of inventories recognized as expenses

确认为费用的存货成本

(12,681)

(13,199)

Royalty fees

特许权使用费

(3,361)

(2,421)

Inventory impairments

存货减值

(5,147)

(1,675)

Total

总计

(21,189)

(17,295)

Costs of inventories recognized as expenses in the first half year of 2026 were US$12.7 million versus US$13.2 million for the first half of 2025 and relates to actual product sales of RUCONEST and Joenja.

2026年上半年确认为费用的存货成本为1,270万美元，而2025年同期为1,320万美元，这与RUCONEST和Joenja的实际产品销售相关。

Pharming expensed royalty fees to Novartis on Joenja sales, amounting to US$3.4 million in the first half of 2026 (first half of 2025: US$2.4 million).

Pharming将Joenja销售相关的特许权使用费计入费用，支付给诺华，2026年上半年金额为340万美元（2025年上半年：240万美元）。

Inventory impairments amounted to US$5.1 million (1H 2025: US$1.7 million) and stems from the valuation of the inventories against lower net realizable value and mainly relates to material no longer expected to be used for commercial sales.

存货减值金额为510万美元（2025年上半年：170万美元），源于按较低的净可变现价值对存货进行估值，主要涉及预计不再用于商业销售的材料。

Other operating costs

其他运营成本

Other operating costs decreased to US$146.9 million in the first half of 2026 compared to US$153.4 million in the first half year of 2025.

其他运营成本从2025年上半年的1.534亿美元下降至2026年上半年的1.469亿美元。

Employee benefits are charged to research and development costs, general and administrative costs, or marketing and sales costs based on the nature of the services provided. Employee benefits of production related employees have been included in the value of inventories.

员工福利根据所提供服务的性质，计入研发费用、一般及管理费用或营销及销售费用。与生产相关的员工福利已计入存货价值。

Depreciation and amortization charges amounted to US$6.0 million in the first half of 2026 compared to US$5.3 million the first half year of 2025, and related to the following:

2026年上半年，折旧和摊销费用为600万美元，而2025年上半年为530万美元，具体涉及以下项目：

Amounts in US$ ‘000

金额（单位：千美元）

1H 2026

2026年上半年

1H 2025

2025年上半年

Property, plant and equipment

物业、厂房及设备

(616)

(650)

Right-of-use assets

使用权资产

(1,494)

(1,475)

Intangible assets

无形资产

(3,860)

(3,159)

Total

总计

(5,970)

(5,284)

10.

Finance income (expenses)

财务收入（费用）

Amounts in US$ ‘000

金额（单位：千美元）

1H 2026

2026年上半年

1H 2025

2025年上半年

Foreign currency results

外币结果

5,303

—

Interest income

利息收入

1,816

1,263

一千二百六十三

Other finance income

其他财务收入

7,119

1,263

Foreign currency results

外币业绩

—

(4,549)

Fees and expenses on repayment and issuance convertible bonds

可转换债券发行及偿还相关的手续费和支出

—

Amortization and interest on convertible bonds

可转换债券的摊销与利息

(5,179)

(4,586)

Interest leases

利息租赁

(192)

(516)

（516）

Other finance expenses

其他财务费用

(32)

(136)

Other finance expenses

其他财务费用

(5,403)

(9,787)

Total other finance income and expenses

其他财务收支总额

1,716

(8,524)

Foreign currency results primarily reflect movements in the EUR/USD exchange rate. The strengthening of the U.S. dollar against the euro during the first half of 2026 (compared with a weakening during the first half of 2025) generated foreign exchange gains. These gains were mainly attributable to the revaluation of the U.S.

外币业绩主要反映欧元/美元汇率的变动。2026年上半年美元兑欧元走强（而2025年上半年则为走弱），由此产生汇兑收益。这些收益主要 attributable to 美国的重新估值。

dollar-denominated cash and marketable securities balances held by euro functional currency entities and euro-denominated monetary assets and liabilities held by the U.S. dollar functional currency entity..

以欧元为功能货币的实体持有的美元现金及有价证券余额，以及以美元为功能货币的实体持有的欧元货币性资产和负债。

Interest income increased compared with the first half of 2025 due to a higher average balance of cash and marketable securities following the completion of the Abliva acquisition in the first half of 2025, as well as higher effective yields earned on cash and cash equivalents.

利息收入较2025年上半年有所增加，原因是2025年上半年完成对Abliva的收购后，现金及有价证券的平均余额上升，同时现金及现金等价物的实际收益率也有所提高。

11.

Income tax (expenses)

所得税（费用）

Income tax expenses are recognized in each interim period based on the best estimate of the weighted average annual effective income tax rate expected for the full financial year.

所得税费用根据对整个财务年度预期的加权平均年有效所得税率的最佳估计，在每个中期期间确认。

12.

Investments

投资

Investments accounted for using the equity method

采用权益法核算的投资

The asset relates to an investment in the ordinary shares of BioConnection Investments B.V. (“BioConnection”). In the Board of Directors’ judgement, the investment in BioConnection constitutes an investment in an associated company and is therefore not consolidated. Pharming has significant influence but does not have control of BioConnection and is embargoed by a shareholder’s agreement between the shareholders of BioConnection from influencing any activity between the two parties which is in any significant way different from the relationship which existed between the two prior to the investment..

该资产涉及对 BioConnection Investments B.V.（“BioConnection”）普通股的投资。董事会认为，对 BioConnection 的投资构成对联营公司的投资，因此不纳入合并报表范围。Pharming 对 BioConnection 具有重大影响，但并未取得控制权；同时，根据 BioConnection 股东之间的股东协议，Pharming 被禁止影响双方之间任何与投资前既存关系存在显著差异的活动。

The carrying amount of this investment has changed as follows:

该项投资的账面价值变动如下：

Amounts in US$ ‘000

金额以千美元计

Period to June 30, 2026

截至2026年6月30日的期间

Period to December 31, 2025

截至2025年12月31日的期间

Balance at January 1

1月1日余额

1,944

466

四百六十六

Share in net profit (loss) for the period

本期净利润（亏损）份额

168

623

六百二十三

Equity contribution

股权出资

—

739

七百三十九

Currency translation

货币折算

(57)

116

一百一十六

Balance at end of period

期末余额

2,055

两千零五十五

1,944

Investment in debt instruments designated as at FVTPL

指定为以公允价值计量且其变动计入当期损益的债务工具投资

The asset relates to the preference share in BioConnection Investments B.V. The Board of Directors made an assessment on the accounting treatment of the preference share obtained. The Board concluded that the asset should be recognized as a financial asset (debt instrument) measured at initial recognition at fair value, subsequently measured at fair value through profit and loss.

该资产涉及 BioConnection Investments B.V. 的优先股。董事会对取得的优先股的会计处理进行了评估。董事会得出结论，该资产应确认为金融资产（债务工具），在初始确认时以公允价值计量，后续以公允价值计量且其变动计入当期损益。

The fair value is calculated on a yearly basis using the forward-looking Black-Scholes-Merton (“BSM”) financial instrument pricing framework. No events or matters are known as of the date of this report which would lead to a significant impact in the fair value of the asset, compared to December 31, 2025..

公允价值采用前瞻性的布莱克-斯科尔斯-默顿（“BSM”）金融工具定价框架按年度计算。截至本报告日期，未发现任何会导致资产公允价值相较于2025年12月31日发生重大变动的事件或事项。

The carrying amount of this investment has changed as follows:

该项投资的账面价值变动如下：

Amounts in US$ ‘000

金额（千美元）

Period to June 30, 2026

截至2026年6月30日的期间

Period to December 31, 2025

截至2025年12月31日的期间

Balance at January 1

1月1日余额

6,703

3,767

Fair value changes

公允价值变动

—

2,345

Currency translation

货币折算

(183)

591

五百九十一

Balance at end of period

期末余额

6,520

6,703

13.

Deferred tax assets

递延所得税资产

The deferred tax assets decreased mainly due to foreign exchange effects and changes in temporary differences.

递延所得税资产减少，主要原因是外汇影响和暂时性差异的变化。

14.

Inventories

存货

Inventories include batches of Joenja and RUCONEST and related work in progress.

库存包括多批次的Joenja和RUCONEST以及相关的在制品。

Amounts in US$ ‘000

金额（千美元）

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Finished goods

成品

16,406

18,214

Work in progress

进行中

49,022

46,688

Balance at end of period

期末余额

65,428

64,902

Changes in the adjustment to net realizable value:

可变现净值调整的变化：

Amounts in US$ ‘000

金额（千美元）

Period to June 30, 2026

截至2026年6月30日的期间

Period to December 31, 2025

截至2025年12月31日的期间

Balance at January 1

1月1日余额

(13,060)

(8,663)

Addition to impairment

减值附加

(6,195)

(6,193)

Release of impairment

减值转回

206

538

Usage of impairment

减值的使用

2,011

2,522

Currency translation

货币折算

455

四百五十五

(1,264)

Balance at end of period

期末余额

(16,583)

(13,060)

The inventory valuation at June 30, 2026, of US$65.4 million (December 31, 2025: US$64.9 million) is stated net of an impairment of US$16.6 million (December 31, 2025: US$13.1 million). The impairment relates to the write down of inventories to their net realizable value.

截至2026年6月30日，存货账面价值为6,540万美元（2025年12月31日：6,490万美元），已扣除1,660万美元的减值准备（2025年12月31日：1,310万美元）。该减值涉及将存货账面价值减记至其可变现净值。

Inventories are available for use in commercial, preclinical and clinical activities. Estimates have been made with respect to the ultimate use or sale of product, taking into account current and expected sales as well as preclinical and clinical programs. These estimates are reflected in the additions to the impairment.

库存可用于商业、临床前和临床试验活动。已就产品的最终用途或销售作出估计，同时考虑了当前及预期的销售情况以及临床前和临床试验项目。这些估计反映在减值准备的增加中。

The costs of materials used in research and development activities are presented under the research and development costs..

研发活动中使用的材料成本列示于研发费用项下。

The main portion of inventories at June 30, 2026, have expiration dates starting beyond 2026 and are all expected to be sold and/or used before expiration.

截至2026年6月30日，库存的主要部分保质期均在2026年之后，且预计全部将在保质期内售出和/或使用完毕。

Cash, cash equivalents and marketable securities

现金、现金等价物及有价证券

Amounts in US$ ‘000

金额（千美元）

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Investments in money market funds

货币市场基金投资

—

33,796

Marketable securities

有价证券

—

33,796

Cash held at banks

存放于银行的现金

60,007

六万零七

145,305

Investments in money market funds

货币市场基金投资

98,274

九万八千二百七十四

—

Cash and cash equivalents

现金及现金等价物

158,281

145,305

Total liquidity

总流动性

158,281

179,101

Since April 1, 2026, the marketable securities are considered to be cash equivalents as they are managed from that date as part of the Group’s total liquidity position and are held to meet potential short-term cash commitments rather than for investment purposes. The money market funds consist of LVNAV money market funds regulated under the EU Money Market Fund Regulation, which imposes liquidity, maturity, diversification and credit quality requirements broadly comparable to those applicable to SEC Rule 2a‑7 money market funds.

自2026年4月1日起，有价证券被视为现金等价物，因为从该日期起，它们作为集团整体流动性状况的一部分进行管理，并持有用于满足潜在的短期现金支付承诺，而非出于投资目的。货币市场基金包括根据欧盟《货币市场基金法规》受监管的LVNAV货币市场基金，该法规在流动性、期限、分散化和信用质量方面施加的要求，大致与美国证券交易委员会（SEC）第2a-7条规则适用的货币市场基金的要求相当。

The carrying value includes accrued interest of US$0.3 million as of June 30, 2026 (December 31, 2025: US$0.1 million)..

截至2026年6月30日，账面价值包含应计利息30万美元（2025年12月31日：10万美元）。

Cash is free at disposal of the Company.

现金可由公司自由支配。

16.

Equity

股权

The Company’s authorized share capital amounts to €10.56 million (US$12.0 million) and is divided into 1,056,000,000 ordinary shares with a nominal value of €0.01 each. All 707,781,240 shares outstanding at June 30, 2026, have been fully paid-up. Other reserves include those reserves related to currency translation, share-based compensation expenses and other equity-settled transactions.

公司的法定股本为1,056万欧元（1,200万美元），分为1,056,000,000股普通股，每股面值0.01欧元。截至2026年6月30日，所有已发行的707,781,240股均已全额缴足。其他储备包括与外币折算、以股份为基础的薪酬费用以及其他以权益结算的交易相关的储备。

。

Please refer to the Condensed consolidated interim statement of changes in Equity.

请参阅简明合并中期权益变动表。

The other reserves are made up as shown in the below table.

其他储备的构成如下表所示。

Amounts in US$ ‘000

金额（千美元）

Legal reserve Currency translation reserve (CTA)

法定准备金货币折算准备金（CTA）

Legal Reserve Capitalized development cost

法定准备金资本化开发成本

Reserve Convertible bond

可转换债券准备金

Total

总计

Balance at January 1, 2025

2025年1月1日余额

(12,510)

七十六

12,225

(209)

Movement in the period

期间变动

26,148

(31)

—

26,117

Balance at June 30, 2025

截至2025年6月30日的余额

13,638

四十五

12,225

25,908

Balance at January 1, 2026

2026年1月1日余额

14,941

四十四

13,835

28,819

Movement in the period

期间变动

(8,057)

(44)

（44）

(377)

(8,477)

Balance at June 30, 2026

截至2026年6月30日的余额

6,884

—

13,458

20,342

17.

Convertible bonds

可转换债券

In April 2024, the Company issued €100.0 million (US$113.9 million, based on the EUR/USD exchange rate as of June 30, 2026) aggregate principal amount of 4.50% convertible bonds due 2029.

2024年4月，本公司发行了本金总额为1亿欧元（按截至2026年6月30日的欧元/美元汇率折算为1.139亿美元）的2029年到期的4.50%可转换债券。

The movements of the convertible bonds were as follows:

可转换债券的变动情况如下：

Amounts in US$ ‘000

金额（单位：千美元）

Period to June 30, 2026

截至2026年6月30日的期间

Period to December 31, 2025

截至2025年12月31日的期间

Balance at January 1

1月1日余额

98,055

82,399

Interest paid (cash flow)

支付的利息（现金流）

(2,630)

(5,067)

Amortization

摊销

4,230

8,752

Accrued interest

应计利息

949

九百四十九

933

九百三十三

Currency translation

货币折算

(2,734)

11,038

Carrying value at end of period

期末账面价值

97,870

98,055

九万八千零五十五

18.

Earnings per share and diluted shares

每股收益与稀释后股数

Basic earnings per share is calculated based on the weighted average number of ordinary shares outstanding during the period. Diluted earnings per share in the case of a profit is computed based on the weighted average number of ordinary shares outstanding including the dilutive effect of shares to be issued in the future under certain arrangements such as option plans.

基本每股收益根据当期发行在外普通股的加权平均数计算。在盈利情况下，稀释每股收益根据包含期权计划等特定安排下未来将发行股份的稀释效应在内的发行在外普通股加权平均数计算。

However, as the net result represents a loss, the diluted earnings per share are equal to the basic earnings per share. For 1H 2026 and 1H 2025, the basic and diluted earnings per share are:.

然而，由于净结果为亏损，稀释每股收益等于基本每股收益。2026年上半年和2025年上半年的基本每股收益和稀释每股收益分别为：

1H 2026

2026年上半年

1H 2025

2025年上半年

Net profit (loss) attributable to equity owners of the parent (in US $ '000)

归属于母公司股东的净利润（亏损）（单位：千美元）

(3,575)

(10,025)

Weighted average shares outstanding (in '000)

加权平均流通股数（单位：千股）

705,383

677,743

Basic profit (loss) per share (in US$)

每股基本收益（亏损）（美元）

(0.005)

(0.015)

Weighted average fully-diluted shares outstanding (in '000)

加权平均完全稀释后流通股股数（单位：千股）

749,519

744,282

Fully-diluted profit per share (in US$)

完全稀释每股收益（美元）

(0.005)

(0.015)

Diluted shares

稀释股

The composition of the number of shares and share rights outstanding as well as authorized share capital as per June 30, 2026 is provided in the table below:

截至2026年6月30日，已发行股份及股份权利数量以及授权股本的构成如下表所示：

Amounts in '000

金额单位：千

December 31, 2025

2025年12月31日

Shares issued

已发行股份

Other

其他

June 30, 2026

2026年6月30日

Issued shares

已发行股份

701,680,440

七亿零一百六十八万零四百四十

6,100,800

六百一十万零八百

—

707,781,240

七亿零七百八十一万二千二百四十

RSU

限制性股票单位

19,853,668

一千九百八十五万三千六百六十八

(726,337)

(2,185,735)

16,941,596

Options

选项

8,479,908

(2,758,750)

(60,000)

5,661,158

Convertible bonds

可转换债券

81,492,951

八千一百四十九万二千九百五十一

—

81,492,951

LTIP

长期激励计划

19,636,796

(3,287,161)

3,818,129

20,167,764

Fully-diluted shares

完全稀释股数

831,143,763

八亿三千一百一十四万三千七百六十三

(671,448)

1,572,394

832,044,709

八亿三千二百零四万四千七百零九

Available for issue

可供发行

224,856,237

二亿二千四百八十五万六千二百三十七

671,448

(1,572,394)

223,955,291

2亿2395万5291

Authorized share capital

法定股本

1,056,000,000

10.56亿

—

1,056,000,000

10.56亿

19.

Financial risk management and fair value

财务风险管理与公允价值

Financial risk management

财务风险管理

Pharming is exposed to several financial risks: market risks (being currency risk and interest rate risk), credit risks and liquidity risks. The Board of Directors and the Executive Committee are responsible for the management of currency, interest, credit and liquidity risks and as such ultimately responsible for decisions taken in this field.

Pharming 面临多种财务风险：市场风险（包括汇率风险和利率风险）、信用风险以及流动性风险。董事会和执行委员会负责管理汇率、利率、信用和流动性风险，并因此对这些领域内作出的决策承担最终责任。

The Group’s exposure to financial risks has not materially changed during the period..

本集团在期间内面临的财务风险未发生重大变化。

Fair value

公允价值

The following table provides information on the fair value of financial instruments not measured at fair value as at the reporting date:

下表提供了在报告日未按公允价值计量的金融工具的公允价值信息：

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Carrying value

账面价值

Fair value

公允价值

Carrying value

账面价值

Fair value

公允价值

Liabilities:

负债：

Convertible Bond (incl. equity component)

可转换债券（含权益部分）

111,328

145,807

111,890

157,481

For financial instruments not included in the table above, the carrying amount is a reasonable approximation of fair value.

对于未包含在上述表格中的金融工具，其账面价值是公允价值的合理近似值。

The following table presents information on the fair value measurement hierarchy of financial instruments measured at fair value:

下表列示了以公允价值计量的金融工具的公允价值计量层级信息：

June 30, 2026

2026年6月30日

December 31, 2025

2025年12月31日

Level 1

一级

Level 3

三级

Total

总计

Level 1

等级 1

Level 3

3级

Total

总计

Items measured at fair value:

以公允价值计量的项目：

Money market funds

货币市场基金

98,274

—

98,274

33,796

—

33,796

Investments in debt instruments designated as at FVTPL

指定为以公允价值计量且其变动计入当期损益的债务工具投资

—

6,520

—

6,703

Items for which fair value is disclosed:

披露公允价值的项目：

Convertible Bond (incl. equity component)

可转换债券（含权益部分）

145,807

—

145,807

157,481

—

157,481

Further information on the investments in debt instruments designated as at FVTPL is included in note 12.

有关指定为以公允价值计量且其变动计入当期损益的债务工具投资的进一步信息，请参阅附注12。

During the six-month period ended June 30, 2026, there have been no changes related to the fair value hierarchy. Comparative information was updated for consistency.

截至2026年6月30日的六个月期间，公允价值层级未发生任何变化。为保持一致性，已对比较信息进行了更新。

20. Related party transactions

20. 关联方交易

There are no material changes in the nature, scope, and scale in this reporting period compared to last year. More information is included in note 24 to the consolidated financial statements as at and for the year ended December 31, 2025.

与去年相比，本报告期在性质、范围和规模方面均无重大变化。更多信息载于截至2025年12月31日止年度的合并财务报表附注24。

21. Events since the end of the reporting period

21. 报告期结束后的事项

There were no significant events since the end of the reporting period.

自报告期结束以来，未发生重大事项。

Attachment

附件

Pharming Group reports 2Q_1H26 results_EN_30JULY2026

Pharming Group 公布2026年第二季度及上半年业绩_EN_2026年7月30日

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