Researchers unveil the health risks associated with the co-occurrence of diabetes and sarcopenia in the elderly, with respect to overall and cardiovascular mortalitySEOUL, South Korea, Jan. 24, 2024 /PRNewswire/ -- Diabetes mellitus and sarcopenia pose a substantial challenge to public health, especially among the elderly.

2024年1月24日，研究人员揭示了老年人糖尿病和骨骼肌减少症并存的整体和心血管死亡率相关的健康风险。韩国首尔，2024年1月24日/新闻专线/--糖尿病和骨骼肌减少症对公共卫生构成了重大挑战，尤其是老年人。

These conditions share common pathophysiological mechanism and are linked bidirectionally, with each contributing to an increased risk of the other. Previous research has shown that both diabetes and sarcopenia are individually linked to serious health complications including cardiovascular conditions that may result in death.

这些疾病具有共同的病理生理机制，并且双向关联，每种疾病都会导致另一种疾病的风险增加。先前的研究表明，糖尿病和肌肉减少症都与严重的健康并发症有关，包括可能导致死亡的心血管疾病。

However, there is limited research on the combined health impact of diabetes and sarcopenia, particularly in vulnerable populations such as the elderly..

然而，关于糖尿病和肌肉减少症对健康的综合影响的研究有限，特别是在老年人等弱势人群中。。

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Diabetes mellitus and sarcopenia independently heighten mortality risks, and their co-occurrence additively amplifies cardiovascular and all-cause mortality in aging populations.

糖尿病和肌肉减少症独立地增加了死亡风险，并且它们的共同发生增加了老年人群的心血管和全因死亡率。

To address this gap, a research team led by Professor Eyun Song and Professor Kyung Mook Choi from the Korea University College of Medicine, South Korea performed a longitudinal study to assess the combined impact of diabetes and sarcopenia on all-cause and cardiovascular death in the South Korean population.

为了弥补这一差距，韩国韩国大学医学院的宋爱云教授和崔京木教授领导的一个研究小组进行了一项纵向研究，以评估糖尿病和肌肉减少症对韩国人群全因死亡和心血管死亡的综合影响。

This study was made available online on 21 August 2023 in Volume 148 Issue 155678 of the journal Metabolism..

这项研究于2023年8月21日在线发布在《新陈代谢》杂志第148卷第155678期。。

The study analyzed data from the Korea National Health and Nutrition Examination Survey (2008–2011) and mortality data from the Korean National Death Registry. The study's findings revealed that the co-occurrence of diabetes and sarcopenia nearly doubled the risk of cardiovascular and all-cause death.

该研究分析了韩国国家健康与营养调查（2008-2011）的数据和韩国国家死亡登记处的死亡率数据。研究结果表明，糖尿病和肌肉减少症的共同发生几乎使心血管疾病和全因死亡的风险增加了一倍。

Notably, the incidence of cardiovascular mortality was significantly elevated in the group exhibiting both diabetes and sarcopenia but not in groups exhibiting either condition..

值得注意的是，糖尿病和肌肉减少症患者的心血管死亡率显着升高，但两种疾病患者的心血管死亡率均未升高。。

Approximately 22%–24% of South Koreans suffer from both diabetes and sarcopenia, a significant portion of the population faces a doubled risk of mortality.Implementing preventive healthcare strategies such as preventing muscle loss in patients with diabetes can potentially mitigate the co-occurrence & high mortality risk associated with both conditions.

大约22%-24%的韩国人同时患有糖尿病和肌肉减少症，相当一部分人口的死亡风险翻了一番。实施预防性医疗保健策略，例如预防糖尿病患者的肌肉损失，可能会减轻与这两种情况相关的共同发生和高死亡率风险。

It is recommended that individuals in the high-risk category incorporate lifestyle changes, regular exercise, and a balanced diet to reduce the likelihood of muscle loss. In fact, elderly patients with diabetes are advised to undergo screenings for sarcopenia to promptly receive care to address the combined threat of these conditions.There is a need to develop new healthcare guidelines aimed at patients with both diabetes and sarcopenia, considering their unique health challenges and risks.

建议高危人群改变生活方式，定期锻炼和均衡饮食，以减少肌肉损失的可能性。事实上，建议老年糖尿病患者进行骨骼肌减少症筛查，以便及时接受护理，以应对这些疾病的综合威胁。考虑到糖尿病和肌肉减少症患者独特的健康挑战和风险，有必要针对他们制定新的医疗保健指南。

Adding to this, Dr. Song says, 'In the future, it might become mandatory for patients with diabetes to receive healthcare assessments that capture their muscle mass, muscle strength, and physical performance during clinical visits and for patients with sarcopenia to monitor their blood glucose levels and make lifestyle changes to maintain their glycemic status.'Summarizing the results of their research Dr.

除此之外，宋博士说，“未来，糖尿病患者可能必须接受医疗保健评估，以记录他们在临床就诊期间的肌肉质量、肌肉力量和身体表现，肌肉减少症患者可能必须监测他们的血糖水平，并改变生活方式以维持血糖状态。”总结他们的研究结果。

Choi says, 'When diabetes and sarcopenia 'coexist,' there is an additive increase in all-cause and cardiovascular mortalities which underscores the importance of careful screening and prevention strategies in high-risk populations. Additionally, further research is needed to understand the intricate mechanisms linking diabetes and sarcopenia to and develop targeted treatments to enhance health outcomes.'In conclusion, healthcare systems may benefit from investing in preventive measures for sarcopenia & diabetes by potentially reduci.

Choi说，“当糖尿病和肌肉减少症共存时，全因死亡率和心血管死亡率会增加，这突显了在高危人群中仔细筛查和预防策略的重要性。此外，还需要进一步的研究来了解糖尿病和肌肉减少症与糖尿病之间的复杂机制，并开发有针对性的治疗方法来改善健康状况。”总之，医疗保健系统可能会受益于通过潜在的减少来投资肌肉减少症和糖尿病的预防措施。