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The FDA recently approved the first tumor-infiltrating lymphocyte, or TIL, therapy to treat advanced melanoma, and 27 institutions have so far been authorized to deliver the treatment. Federal regulators approved Amtagvi — made my Iovance Biotherapeutic — Feb. 16 to treat adults with unresectable or metastatic melanoma, which is when the cancer cannot be surgically removed or has spread to other parts of the body.
FDA最近批准了第一种治疗晚期黑色素瘤的肿瘤浸润淋巴细胞(TIL)疗法,迄今已有27家机构被授权提供该疗法。联邦监管机构于2月16日批准Amtagvi(制造my Iovance Biotherapeutic)治疗成人不可切除或转移性黑色素瘤,即癌症无法手术切除或已扩散至身体其他部位。
It is the first cell therapy approved to treat solid tumors. The one-time treatment involves extracting T cells from a patient's own tumor, multiplying them in a laboratory and reinfusing them into the patient in an 'activated' state to attack the cancer. Below is a list of hospitals that have been authorized to offer the treatment, with more expected to be added over time: Northwestern Memorial Hospital in ChicagoUniversity of Chicago Medicine University of Iowa Hospitals and Clinics in Iowa City Barnes-Jewish Hospital in Saint LouisBrown Cancer Center at the University of Louisville (Ky.) James Cancer Hospital at Ohio State University Wexner Medical Center in ColumbusWest Penn Hospital in Pittsburgh University of Kansas Cancer Center in Kansas City Roswell Park Comprehensive Cancer Center in Buffalo, N.Y. University of Tennessee Medical Center in Knoxville, Tenn. Avera Cancer Institute in Sioux Falls, S.D. Northside Hospital in Atlanta MedStar Georgetown University Hospital in Washington, D.C. University of Maryland Medical Center in BaltimoreNewYork-Presbyterian/Columbia University Irving Medical Center in New York City Baylor Scott & White Charles A.
这是第一个被批准用于治疗实体瘤的细胞疗法。一次性治疗包括从患者自身肿瘤中提取T细胞,在实验室中将其繁殖,并将其以“激活”状态重新融合到患者体内以攻击癌症。以下是被授权提供治疗的医院名单,随着时间的推移,预计还会增加更多医院:芝加哥大学西北纪念医院芝加哥医科大学爱荷华大学医院和爱荷华市诊所路易斯维尔大学圣路易斯镇巴恩斯犹太医院癌症中心俄亥俄州立大学詹姆斯癌症医院哥伦布西斯纳医学中心匹兹堡宾夕法尼亚大学堪萨斯大学癌症中心堪萨斯城罗斯威尔公园综合癌症中心纽约州布法罗市田纳西大学医学中心田纳西州诺克斯维尔市阿维拉癌症研究所,亚特兰大S.D.Northside医院华盛顿MedStar乔治敦大学医院巴尔的摩马里兰大学医学中心纽约长老会/哥伦比亚大学欧文医学中心纽约市贝勒·斯科特和怀特·查尔斯A。
Sammons Cancer Center in Dallas Massachusetts General Cancer Center in BostonUF Health Shands Hospital in Gainesville, Fla.Houston Methodist Hospital Orlando (Fla.) Health Cancer Institute Moffitt Cancer Cente.
达拉斯萨蒙斯癌症中心马萨诸塞州通用癌症中心佛罗里达州盖恩斯维尔BostonUF Health Shands医院休斯顿卫理公会医院奥兰多(佛罗里达州)健康癌症研究所Moffitt癌症中心。