Findings show that seborrheic dermatitis is a unique inflammatory skin disease with its own molecular signatureSuggests skin barrier disruption in seborrheic dermatitis is distinct with its own disease-specific pattern SAN DIEGO, Calif., March 09, 2024 (GLOBE NEWSWIRE) -- Arcutis Biotherapeutics, Inc. (Nasdaq: ARQT), a commercial-stage biopharmaceutical company focused on developing meaningful innovations in immuno-dermatology, highlights new research that, for the first time, reveals the gene expression profile of seborrheic dermatitis.

研究结果表明，脂溢性皮炎是一种独特的炎症性皮肤病，具有其自身的分子特征。研究结果表明，脂溢性皮炎的皮肤屏障破坏与其自身的疾病特异性模式不同，加利福尼亚州圣地亚哥，2024年3月9日（环球通讯社）——Arcutis Biotherapeutics，Inc.（纳斯达克：ARQT），一家商业阶段的生物制药公司专注于开发免疫皮肤病学方面有意义的创新，重点介绍了新的研究，该研究首次揭示了脂溢性皮炎的基因表达谱。

The Arcutis sponsored research from The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai was presented in a scientific session at the American Academy of Dermatology (AAD) annual meeting (San Diego, CA, March 8 – 12) and answers key questions on the immune response and associated skin barrier disruption of seborrheic dermatitis.

西奈山伊坎医学院（Icahn School of Medicine）金伯利（Kimberly）和埃里克·J·沃尔德曼（EricJ.Waldman）皮肤病学系（Department of Dermatology）在美国皮肤病学会（AAD）年会（San Diego，CA，3月8日至12日）的一次科学会议上介绍了Arcutis赞助的这项研究，并回答了有关脂溢性皮炎的免疫反应和相关皮肤屏障破坏的关键问题。

“Our research group has had a longstanding interest in defining the immunological pathways that underlie many inflammatory skin diseases, such as atopic dermatitis and psoriasis, shaping our understanding of these diseases and leading to new treatments,” said Emma Guttman-Yassky, MD, PhD, the Waldman Professor of Dermatology and Immunology and Health System Chair of The Department of Dermatology, and Director of the Laboratory for Inflammatory Skin Diseases at the Icahn School of Medicine at Mount Sinai.

医学博士Emma Guttman Yassky说：“我们的研究小组长期以来一直有兴趣确定许多炎症性皮肤病（如特应性皮炎和牛皮癣）的免疫途径，形成我们对这些疾病的理解并导致新的治疗方法。”，沃尔德曼（Waldman）皮肤病学和免疫学教授，西奈山伊坎医学院皮肤病学系主任和炎症性皮肤病实验室主任。

“We are excited to have successfully employed noninvasive tape-stripping techniques developed from studying these diseases to study an understudied and undertreated inflammatory skin disease, seborrheic dermatitis. These findings will help establish the groundwork for greater understanding of this very common condition.” “The pathophysiology of seborrheic de.

“我们很高兴能够成功地利用研究这些疾病而开发的无创胶带剥离技术来研究一种未被充分研究和治疗的炎症性皮肤病，脂溢性皮炎。这些发现将有助于为更好地了解这种非常常见的疾病奠定基础。”“脂溢性皮肤病的病理生理学。