BOSTON, March 28, 2024 /PRNewswire/ -- Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, today announced that it has been awarded a contract for up to $6 million from the Defense Advanced Research Projects Agency (DARPA) to achieve DARPA's objectives under its new Ice Control for cold Environments (ICE) program..

波士顿，2024年3月28日/PRNewswire/--正在构建细胞编程和生物安全领先平台的银杏生物工程（NYSE:DNA）今天宣布，它已获得国防高级研究计划局（DARPA）高达600万美元的合同，以实现DARPA在其新的寒冷环境冰控制（Ice）计划下的目标。。

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Ginkgo Bioworks Awarded DARPA Funding to Produce Novel Proteins to Control Ice in Extreme Cold Weather Environments

银杏生物工程公司（Ginkgo Bioworks）获得美国国防部高级研究计划局（DARPA）的资助，生产新的蛋白质，以在极端寒冷的天气环境中控制冰

DARPA's ICE program aims to develop new materials that control the physical properties of ice crystals to facilitate operations in extreme cold weather environments, which can pose a variety of risks to both personnel health and critical equipment. To meet this goal, Ginkgo, in collaboration with Netrias, Cambium, and consultant Dr.

DARPA的ICE计划旨在开发控制冰晶物理性质的新材料，以促进在极端寒冷天气环境中的操作，这可能对人员健康和关键设备造成各种风险。为了实现这一目标，银杏与Netrias，Cambium和顾问博士合作。

Ran Drori, aims to develop novel biologically-sourced and inspired materials that leverage biological adaptations to cold environments..

Ran Drori旨在开发新的生物来源和灵感材料，利用生物适应寒冷环境。。

The Ginkgo team will work to enable the sustainable production of novel de-icing proteins with ice-modulating behaviors to improve operational efficacy in extreme cold weather environments. These materials will be designed with the goal of meeting U.S. Department of Defense specifications and could potentially be used in solutions with broad commercial applications.

银杏团队将致力于可持续生产具有冰调节行为的新型除冰蛋白，以提高极端寒冷天气环境下的运行效率。这些材料的设计目标是满足美国国防部的规范，并有可能用于具有广泛商业应用的解决方案。

One such application could be a lens coating to prevent frost formation for a range of optics applications from satellites and high altitude imaging instruments to security and wildlife cameras. The aviation and automobile industries could also benefit from de-icing products that facilitate safe operations in icy conditions.

其中一种应用可能是透镜涂层，以防止从卫星和高空成像仪器到安全和野生动物相机的一系列光学应用中结霜。航空和汽车行业也可以从除冰产品中受益，这些产品有助于在结冰条件下安全运行。

Furthermore, a topical frostbite prevention product could be developed for outdoor enthusiasts. If successful, these solutions could impact high value and consumer markets and facilitate replacement of current environmentally harmful de-icing agents..

此外，可以为户外爱好者开发一种局部防冻产品。如果成功，这些解决方案可能会影响高价值和消费市场，并有助于更换目前对环境有害的除冰剂。。

The team plans to leverage Ginkgo Protein Services to design, screen, and optimize a library of novel proteins that demonstrate ice-modulating behaviors. Ginkgo will design a library of proteins using metagenomic discovery and de novo computational design to source known, naturally occurring ice-modulating behavior proteins.

该团队计划利用银杏蛋白质服务来设计、筛选和优化一个新的蛋白质库，这些蛋白质可以表现出冰的调节行为。银杏将使用宏基因组发现和从头计算设计来设计蛋白质库，以寻找已知的天然存在的冰调节行为蛋白质。

During the discovery phase, predictive models will be used to iterate Design–Build–Test–Optimize loops, maximizing discovery of proteins with ice inhibition, induction, and low-adhesion properties. Throughout the process, Ginkgo will selectively screen promising proteins with further high-performance, application-specific characterization to inform the final down selection.Jason Kelly, CEO and co-founder of Ginkgo Bioworks: 'We are honored to be selected by DARPA to work on this program to facilitate sustained cold weather operations.

在发现阶段，预测模型将用于迭代设计-构建-测试-优化循环，最大限度地发现具有冰抑制，诱导和低粘附特性的蛋白质。在整个过程中，银杏将选择性地筛选有前途的蛋白质，并进一步进行高性能，特定于应用的表征，以告知最终的向下选择。Ginkgo Bioworks首席执行官兼联合创始人杰森·凯利（JasonKelly）：“我们很荣幸被DARPA选中参与这一项目，以促进持续的寒冷天气操作。

Building high-throughput libraries of candidate proteins is possible thanks to Ginkgo's unique and differentiated data assets. Biology offers us a myriad of ways to adapt to our environment, and synthetic biology allows us to tap into nature's capabilities and apply them to our own needs. We look forward to the products that the ICE program generates, which may enable enhanced safety and proficiency across various use cases.'To learn more about Ginkgo Protein Services, please visit https://www.ginkgobioworks.com/offerings/protein-services/.If you are interested in working with Ginkgo for the public sector, check out our Offerings for Governments page.About Ginkgo BioworksGinkgo Bioworks is the leading horizontal platform for cell programming, providing flexible, end-to-end services that solve challenges for organizations across diverse markets, from food and agriculture to pharmaceuticals to industrial and specialty ch.

由于银杏独特且差异化的数据资产，建立候选蛋白质的高通量文库是可能的。生物学为我们提供了无数种适应环境的方法，合成生物学使我们能够利用大自然的能力并将其应用于我们自己的需求。我们期待着ICE计划产生的产品，这可能会增强各种用例的安全性和熟练性。”欲了解更多有关银杏蛋白服务的信息，请访问https://www.ginkgobioworks.com/offerings/protein-services/.If如果您有兴趣为公共部门与银杏合作，请访问我们的政府产品页面。关于银杏生物工程银杏生物工程是细胞编程的领先水平平台，提供灵活的端到端服务，为不同市场的组织解决挑战，从食品和农业到制药，再到工业和专业技术。