After years relying on the U.S. government to stockpile and distribute Jynneos, Bavarian Nordic is launching the mpox vaccine into the commercial market.Jynneos, the only FDA-approved mpox vaccine, is now commercially available in the U.S., Bavarian Nordic announced Tuesday. The commercial rollout means that interested individuals can access the shot at local pharmacies and physician offices, in addition to the limited number of clinics designated by health authorities.The launch builds on Jynneos’ availability through public health channels since an mpox—then known as monkeypox—outbreak in 2022.

多年来，巴伐利亚北欧公司一直依赖美国政府储存和分发Jynneos，现在正将mpox疫苗推向商业市场。巴伐利亚北欧周二宣布，唯一获得FDA批准的mpox疫苗Jynneos现已在美国上市。商业推广意味着，除了卫生部门指定的数量有限的诊所外，感兴趣的个人还可以在当地药店和医生办公室获得疫苗。自2022年mpox爆发猴痘（monkeypox）以来，Jynneos通过公共卫生渠道的可用性为此次发布奠定了基础。

It also follows a unanimous decision in October from the U.S. CDC’s Advisory Committee on Immunization Practices to recommend Jynneos as a routine vaccination in adults at risk of mpox infection, backing the shot’s use beyond an outbreak.People at risk of mpox include men who have sex with men and others who engage in risky sex practices, according to the CDC.About 2 million individuals in the U.S.

此前，美国疾病预防控制中心免疫实践咨询委员会于10月一致决定，建议将Jynneos作为mpox感染风险成年人的常规疫苗接种，支持在疫情爆发后使用该疫苗。据疾病预防控制中心称，mpox风险人群包括男男性行为者和其他从事危险性行为的人。美国约有200万人。

are eligible for Jynneos under the CDC’s new recommendation, Bavarian Nordic said, citing CDC estimates. About 60% of those people remain completely unvaccinated, and 15% have received only one of the two vaccine doses.A real-world case-match study conducted in 12 U.S. jurisdictions previously showed that Jynneos, when given in two doses, was estimated to be 85.9% effective against mpox.

巴伐利亚州北欧人援引疾病预防控制中心的估计称，根据疾病预防控制中心的新建议，他们有资格获得Jynneos。大约60%的人仍然没有接种疫苗，15%的人只接种了两剂疫苗中的一剂。之前在美国12个司法管辖区进行的一项现实案例匹配研究表明，Jynneos在两次给药时，对mpox的有效率估计为85.9%。

At one dose, the vaccine was found to be 75.2% effective.RelatedBavarian Nordic's Jynneos vaccine up to 86% effective against mpox: CDCAlthough mpox is no longer considered an emergency, infections still occur at an average monthly rate of about 200 cases in the U.S., with reports across most of the states so far this year.

一剂疫苗的有效率为75.2%。相关的巴伐利亚北欧Jynneos疫苗对mpox的有效率高达86%：CDC虽然mpox不再被认为是紧急情况，但在美国，感染仍然以平均每月约200例的速度发生，今年迄今为止，大多数州都有报告。

More than 32,000 mpox cases have been reported in the U.S. since the last out.

自上次调查以来，美国已报告超过32000例mpox病例。