CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vizgen, Inc. the life science company dedicated to improving human health by visualizing single-cell spatial genomics information, today unveiled the MERSCOPE® Ultra Platform and MERFISH 2.0 chemistry at the AACR 2024 Annual Meeting. These powerful tools are uniquely suited to supporting basic and translational research and will be commercially available in the second half of the year..

马萨诸塞州剑桥市。-（商业新闻短讯）--Vizgen，Inc.是一家致力于通过可视化单细胞空间基因组学信息来改善人类健康的生命科学公司，今天在AACR 2024年会上发布了MERSCOPE®Ultra平台和MERFISH 2.0化学。这些强大的工具非常适合支持基础研究和转化研究，将于今年下半年上市。。

The MERSCOPE Ultra Platform is a powerful new high plex in situ spatial multiomic analysis system. MERSCOPE Ultra features the optimum combined capabilities of imaging area and throughput in a spatial transcriptomics imaging platform. The platform is capable of processing 3 cm2 of tissue on a single slide and acquires images at more than double the speed of the MERSCOPE Platform.

MERSCOPE Ultra平台是一种功能强大的新型高倍原位空间多组学分析系统。MERSCOPE Ultra在空间转录组学成像平台中具有成像面积和吞吐量的最佳组合功能。该平台能够在单个载玻片上处理3 cm2的组织，并以MERSCOPE平台两倍以上的速度获取图像。

Engineered for high-performance and optimized for throughput, MERSCOPE Ultra provides researchers with an industry-leading combination of imageable area, speed, and data quality to accelerate discovery and maximize the biology measured from every sample. Further, the system is the only spatial platform to offer two different size flow cells enabling users to adjust reagent consumption based on area imaged..

MERSCOPE Ultra专为高性能而设计，并针对吞吐量进行了优化，为研究人员提供了业界领先的可成像面积，速度和数据质量的组合，以加速发现并最大程度地提高从每个样品中测得的生物学。此外，该系统是唯一提供两个不同尺寸流通池的空间平台，使用户能够根据成像面积调整试剂消耗量。。

'The spatial biology market is advancing rapidly, driven by the valuable insights from spatial readouts. Meanwhile, the leap to larger imaging areas will mark a new wave of expansion, broadening the scope and depth of scientific inquiry,' said Stephane Budel, Partner, DeciBio.

“在空间读数的宝贵见解的推动下，空间生物学市场正在迅速发展。DeciBio合伙人斯蒂芬·布德尔（StephaneBudel）说，与此同时，向更大成像领域的飞跃将标志着新一波的扩张，扩大科学研究的范围和深度。

Vizgen’s MERFISH 2.0 chemistry leverages improved RNA anchoring and signal enhancement to increase MERFISH’s sensitivity and reproducibility. The optimized chemistry enables broader sample compatibility, improving MERFISH’s performance in archival Formalin-Fixed Paraffin-Embedded (FFPE) samples, and further improving its sensitivity.

Vizgen的MERFISH 2.0化学利用改进的RNA锚定和信号增强来提高MERFISH的灵敏度和可重复性。优化的化学方法可以实现更广泛的样品相容性，提高MERFISH在档案福尔马林固定石蜡包埋（FFPE）样品中的性能，并进一步提高其灵敏度。

The company is presenting a poster at AACR showcasing improved sensitivity, reproducibility, and biological accuracy in degraded RNA cancer samples to demonstrate the power of this enhanced chemistry..

该公司在AACR上展示了一张海报，展示了降解RNA癌症样品的灵敏度，重现性和生物学准确性的提高，以证明这种增强化学的力量。。

“MERSCOPE Ultra elevates our in situ imaging capabilities to unprecedented heights, delivering enhanced throughput and adaptability that supports a range of research to accelerate discovery and biological insights,” said Terry Lo, President and CEO of Vizgen. “MERFISH 2.0 chemistry further improves on MERFISH technology, particularly in FFPE and archival samples.

Vizgen总裁兼首席执行官Terry Lo表示：“MERSCOPE将我们的原位成像能力提升到前所未有的高度，提高了吞吐量和适应性，支持了一系列研究，以加速发现和生物学见解。”。“MERFISH 2.0化学进一步改进了MERFISH技术，特别是在FFPE和档案样本中。

Along with our recent addition of 1000 plex custom panel design capabilities, these solutions provide researchers with a powerful spatial omics solution.”.

随着我们最近增加的1000-plex定制面板设计功能，这些解决方案为研究人员提供了强大的空间组学解决方案。”。

AACR Poster Presentation Details

AACR海报展示详情

Title: Improved spatially resolve single-cell transcriptomic imaging in archival tissues with MERSCOPE

标题：使用MERSCOPE改进档案组织中的空间分辨率单细胞转录组成像

Presenter: George Emanuel, Scientific Co-founder, Senior Director of Technology and Partnerships

主持人：乔治·伊曼纽尔（GeorgeEmanuel），科学联合创始人，技术与合作高级总监

Abstract Presentation Number: LB333

摘要介绍编号：LB333

Time: Tuesday, April 9, 1:30 – 5:00 pm

时间：4月9日星期二下午1:30–5:00

About Vizgen®

关于Vizgen®

Vizgen is dedicated to pioneering the next generation of genomics, providing tools that demonstrate the possibilities of in situ single-cell spatial genomics. The company has established the benchmark in spatial genomics and continues to drive industry innovation, delivering the highest sensitivity as well as excellent specificity and accuracy in cell segmentation.

Vizgen致力于开创下一代基因组学，提供证明原位单细胞空间基因组学可能性的工具。该公司建立了空间基因组学的基准，并继续推动行业创新，在细胞分割中提供最高的灵敏度以及优异的特异性和准确性。

These tools enable researchers to gain new insight into the biological systems that govern human health and disease with spatial context. Vizgen’s MERSCOPE® Platform enables massively multiplexed, genome-scale nucleic acid imaging with high accuracy and unrivaled detection efficiency at subcellular resolution.

这些工具使研究人员能够在空间背景下对控制人类健康和疾病的生物系统获得新的见解。Vizgen的MERSCOPE®平台能够在亚细胞分辨率下以高精度和无与伦比的检测效率实现大规模多路复用的基因组规模核酸成像。

MERSCOPE provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, cell and gene therapy, and is an essential tool for accelerating drug discovery and development. For more information, go to www.vizgen.com.

MERSCOPE为肿瘤学、免疫学、神经科学、传染病、发育生物学、细胞和基因治疗等领域的广泛组织规模基础研究和转化医学提供了革命性的见解，是加速药物发现和开发的重要工具。有关更多信息，请访问www.vizgen.com。

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连接社交媒体Twitter、LinkedIn和Facebook。。