Dublin, April 11, 2024 (GLOBE NEWSWIRE) -- The 'Alport Syndrome - Pipeline Insight, 2024' has been added to ResearchAndMarkets.com's offering.The 'Alport Syndrome - Pipeline Insight, 2024,' report provides comprehensive insights about 8+ companies and 10+ pipeline drugs in Alport Syndrome pipeline landscape.

都柏林，2024年4月11日（环球通讯社）--“Alport综合征-管道洞察，2024”已添加到ResearchAndMarkets.com的产品中。“Alport综合征-管道洞察，2024”报告提供了有关Alport综合征管道景观中8多家公司和10多家管道药物的全面见解。

It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.Alport syndrome, also known as hereditary nephritis is a genetic disorder arising from the mutations in the genes encoding alpha-3, alpha-4, and alpha-5 of type 4 collagen (COL4A3, COL4A4, COL4A5) or collagen 4 a345 network.

它涵盖了管道药物概况，包括临床和非临床阶段的产品。它还涵盖了按产品类型，阶段，给药途径和分子类型进行的治疗评估。它进一步突出了该领域中不活跃的管道产品。Alport综合征，也称为遗传性肾炎，是一种遗传性疾病，由编码4型胶原蛋白（COL4A3，COL4A4，COL4A5）或胶原蛋白4 a345网络的α-3，α-4和α-5的基因突变引起。

The type 4 collagen alpha chains are primarily located in the kidneys, eyes, and cochlea. Alport syndrome is X-linked (XLAS) and can be transmitted in an autosomal recessive (ARAS) or autosomal dominant fashion (ADAS). In 1927, the syndrome of hereditary nephritis and deafness was described by a British physician, A.

4型胶原α链主要位于肾脏，眼睛和耳蜗中。Alport综合征是X连锁（XLAS），可以常染色体隐性（ARAS）或常染色体显性（ADAS）传播。1927年，英国医生a。

Cecil Alport. It was observed that hematuria was the most common symptom and males were affected more than females. In 1961, it was named Alport syndrome after having described in multiple family members. It is characterized by renal failure, bilateral sensorineural hearing loss, and eye abnormalities.

塞西尔·阿尔波特。据观察，血尿是最常见的症状，男性比女性受到的影响更大。1961年，在多个家庭成员中进行了描述后，被命名为Alport综合征。它的特征是肾功能衰竭，双侧感觉神经性听力损失和眼睛异常。

Eventually, the patients present with proteinuria, hypertension, progressive loss of kidney function (gradual decline in GFR), and end-stage renal disease. The report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Alport Syndrome pipeline landscape is provided which includes the disease overview a.

最终，患者出现蛋白尿，高血压，肾功能进行性丧失（GFR逐渐下降）和终末期肾病。该报告花费了对当前情景和整个迹象增长前景的全面见解。提供了Alport综合征管道景观的详细图片，其中包括疾病概述A。