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SEATTLE--(BUSINESS WIRE)--Parse Biosciences, a leading provider of accessible and scalable single cell sequencing solutions, today announced the availability of Evercode™ BCR and the expansion of its existing Evercode™ TCR product line. The new BCR solution and updates to the existing TCR product line expand Parse’s single cell portfolio and will enable researchers to study the immune repertoire at unprecedented resolution and scale..
西雅图--(商业新闻短讯)--Parse Biosciences是可访问和可扩展的单细胞测序解决方案的领先供应商,今天宣布推出Evercode™BCR并扩展其现有的Evercode™TCR产品线。新的BCR解决方案和对现有TCR产品线的更新扩展了Parse的单细胞组合,并将使研究人员能够以前所未有的分辨率和规模研究免疫库。。
Evercode BCR allows researchers to capture B cell receptor (BCR) sequences together with gene expression from the same cells. While existing tools struggle to capture the immense diversity of the BCR repertoire, Evercode BCR offers a breakthrough by measuring paired BCR sequences (both heavy and light chains) in up to one million cells in a single experiment.
Evercode BCR允许研究人员捕获B细胞受体(BCR)序列以及来自相同细胞的基因表达。虽然现有工具难以捕获BCR库的巨大多样性,但Evercode BCR通过在单个实验中测量多达100万个细胞中的成对BCR序列(重链和轻链)提供了突破。
This scalable approach enables assignment of BCR clonotypes to various B-cell subtypes and activation states, providing unprecedented resolution and unleashing new capabilities in antibody discovery..
这种可扩展的方法可以将BCR克隆型分配给各种B细胞亚型和激活状态,从而提供前所未有的分辨率并释放抗体发现的新功能。。
Parse has also expanded its Evercode TCR product line to enable detection of both mouse and human TCRs and dramatically improved performance. These updates provide improved sensitivity for both gene expression and TCR detection and are based on the recent release of the Version 3 chemistry for its flagship product, Evercode Whole Transcriptome..
Parse还扩展了其Evercode TCR产品线,以实现对鼠标和人类TCR的检测,并大大提高了性能。这些更新提高了基因表达和TCR检测的灵敏度,并基于其旗舰产品Evercode全转录组的最新版本3化学。。
Both Evercode BCR and TCR are compatible with fixation, which enables researchers to fix and store samples as they arrive and then later batch samples together in a single experiment. This enables time-courses and higher throughput experiments, while minimizing any potential batch effects between samples..
Evercode BCR和TCR都与固定兼容,这使研究人员能够在样品到达时固定和存储样品,然后在单个实验中将样品一起批量处理。这可以实现时间过程和更高吞吐量的实验,同时最大程度地减少样品之间潜在的批次效应。。
“Scaling up cell counts and sample numbers are crucial for achieving impactful results in single cell immune profiling,” said Parse Biosciences co-founder and CTO Charlie Roco. “We are excited about the new capabilities researchers will have with these solutions and to provide them with the unmatched scale required to uncover the vast repertoire diversity of the adaptive immune system.”.
Parse Biosciences联合创始人兼首席技术官Charlie Roco说:“扩大细胞计数和样本数量对于在单细胞免疫分析中取得有影响力的结果至关重要。”。“我们很高兴研究人员将拥有这些解决方案的新功能,并为他们提供无与伦比的规模,以揭示适应性免疫系统的巨大多样性。”。
Parse team members will unveil additional details about Evercode BCR and updates to Evercode TCR at the upcoming American Association of Immunologists (AAI) annual meeting in Chicago on Sunday, May 5 at 10:45 AM in Exhibitor Workshop Theater #1, Hall F1.
Parse团队成员将于5月5日(星期日)上午10:45在芝加哥即将举行的美国免疫学家协会(AAI)年会上公布有关Evercode BCR的更多详细信息以及Evercode TCR的更新。
About Parse Biosciences
关于Parse Biosciences
Parse Biosciences is a global life sciences company whose mission is to accelerate progress in human health and scientific research. Empowering researchers to perform single cell sequencing with unprecedented scale and ease, its pioneering approach is enabling groundbreaking discoveries in cancer treatment, tissue repair, stem cell therapy, kidney and liver disease, brain development, and the immune system..
Parse Biosciences是一家全球生命科学公司,其使命是加速人类健康和科学研究的进展。它的开创性方法使研究人员能够以前所未有的规模和方便地进行单细胞测序,从而在癌症治疗,组织修复,干细胞治疗,肾脏和肝脏疾病,大脑发育以及免疫系统方面取得了突破性的发现。。
Founded based on a transformative technology invented at the University of Washington, Parse has raised over $100 million and is used in nearly 2,000 labs across the world. Its growing portfolio of products includes Evercode Whole Transcriptome, Evercode TCR, Evercode BCR, CRISPR Detect, Gene Capture, and a software tool for data analysis..
Parse基于华盛顿大学发明的一项变革性技术而成立,目前已筹集了一亿多美元,并在全球近2000个实验室中使用。其不断增长的产品组合包括Evercode全转录组,Evercode TCR,Evercode BCR,CRISPR检测,基因捕获和数据分析软件工具。。
Headquartered in Seattle, Washington’s vibrant South Lake Union district, Parse Biosciences recently opened a 34,000 square foot headquarters and state-of-the-art laboratory.
Parse Biosciences总部位于华盛顿活力四射的南湖联合区西雅图,最近开设了34000平方英尺的总部和最先进的实验室。