IRVINE, Calif., May 7, 2024 /PRNewswire/ -- Seragon Biosciences, Inc. today announced the completion of a pre-clinical study on its novel anti-aging candidate, SRN-901. This pivotal study, conducted in mice, was undertaken to evaluate the impact of SRN-901 on aging as well as various health markers..

加利福尼亚州欧文，2024年5月7日/PRNewswire/--Seragon Biosciences，Inc.今天宣布完成其新型抗衰老候选物SRN-901的临床前研究。这项在小鼠中进行的关键研究旨在评估SRN-901对衰老以及各种健康标志物的影响。。

Results from the study show that SRN-901 achieved one of the largest extensions of lifespan and healthspan to date in the treated population. Whole-genome transcriptome sequencing was performed on over 300 mice to assess the effects of SRN-901 at a molecular level. The results highlighted a significant increase in the expression of many genes associated with longevity and a notable reduction in the expression of genes linked to aging.

研究结果表明，SRN-901是迄今为止治疗人群中寿命和健康寿命最大的延长之一。对300多只小鼠进行了全基因组转录组测序，以在分子水平上评估SRN-901的作用。结果表明，许多与寿命相关的基因表达显着增加，而与衰老相关的基因表达显着减少。

Additionally, a metabolic panel revealed beneficial changes in several biomarkers associated with younger biological age..

此外，代谢小组揭示了与年轻生物年龄相关的几种生物标志物的有益变化。。

Other tests were conducted to evaluate the effect of SRN-901 on healthspan, a measure of how long health is maintained over the course of one's life. The study also evaluated physical and cognitive function. Treadmill tests showed significantly enhanced endurance in elderly mice. Frailty scores showed marked improvement in the elderly mice receiving SRN-901, and there was a significant reduction in tumor occurrence in the treated group..

还进行了其他测试来评估SRN-901对healthspan的影响，healthspan是衡量一个人一生中健康维持时间的指标。该研究还评估了身体和认知功能。跑步机测试显示老年小鼠的耐力显着增强。接受SRN-901的老年小鼠的虚弱评分显示出明显的改善，并且治疗组的肿瘤发生率显着降低。。

The research team at Seragon Biosciences is encouraged by the study's results and will conduct further analysis to uncover additional findings. These results will be published once the supplementary analysis is complete.

Seragon Biosciences的研究团队对研究结果感到鼓舞，并将进行进一步分析以发现更多发现。补充分析完成后，将发布这些结果。

About Seragon Biosciences

关于Seragon Biosciences

Seragon Biosciences, Inc., headquartered in Irvine, California, is a research-based biopharmaceutical company dedicated to improving human and animal health through innovative science. Seragon Biosciences is committed to applying cutting-edge scientific and technological advancements to the fields of aging, metabolism, gene therapy, and bioinformatics.

Seragon Biosciences，Inc.，总部位于加利福尼亚州欧文市，是一家以研究为基础的生物制药公司，致力于通过创新科学改善人类和动物的健康。Seragon Biosciences致力于将尖端科学和技术进步应用于衰老，新陈代谢，基因治疗和生物信息学领域。

From the research end to consumer products and clinical applications, Seragon strives to bring people access to the most significant breakthroughs in medicine. For more information, please visit www.seragon.com..

从研究终端到消费品和临床应用，Seragon努力使人们获得医学上最重大的突破。欲了解更多信息，请访问www.seragon.com。。

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SOURCE Seragon Biosciences

来源Seragon Biosciences