Aurora TX, powered by Microfluidic Modulation Spectroscopy (MMS), fully characterizes the structure and stability of RNA, proteins, peptides, and other biomolecules at the touch of a button, including thermal ramping to unlock a greater wealth of insights than ever before.BOXBOROUGH, Mass., May 13, 2024 /PRNewswire/ -- RedShiftBio, a leader in innovative biophysical characterization and bioprocess analytical solutions, proudly announces the launch of Aurora TX at The Protein & Antibody Engineering Summit (PEGS), kicking off on May 13, 2024, in Boston, MA.

Aurora TX由微流体调制光谱（MMS）提供动力，只需按一下按钮，即可充分表征RNA，蛋白质，肽和其他生物分子的结构和稳定性，包括热斜坡，以释放比以往任何时候都丰富的见解。马萨诸塞州博克斯堡，2024年5月13日/PRNewswire/--创新生物物理表征和生物过程分析解决方案的领导者RedShiftBio在2024年5月13日于马萨诸塞州波士顿举行的蛋白质与抗体工程峰会（PEGS）上骄傲地宣布推出Aurora TX。

Aurora TX is the company's latest, most advanced instrument featuring ground-breaking MMS technology, and sets a new standard in biomolecular analysis by providing ultra-sensitive, ultra-precise measurements of biomolecule structure and stability, now enhanced with the addition of thermal ramping capability..

Aurora TX是该公司最新、最先进的仪器，采用开创性的MMS技术，通过提供超灵敏、超精密的生物分子结构和稳定性测量，树立了生物分子分析的新标准，现在通过增加热斜坡能力而得到增强。。

MMS technology, the cornerstone of Aurora TX, provides background-subtracted measurements of a wide range of biomolecules in the formulation of interest and in concentrations ranging from 0.1 mg/mL to >200 mg/mL. This level of accuracy and versatility, coupled with an easy, automated workflow, utilization of 96-well plates, and fully integrated delta analytical software addresses the limitations of existing technologies such as CD and FTIR.

MMS技术是Aurora TX的基石，它可以对感兴趣的配方中的各种生物分子进行背景扣除测量，浓度范围从0.1 mg/mL到>200 mg/mL。这种准确性和多功能性水平，再加上简单的自动化工作流程，96孔板的利用以及完全集成的delta分析软件，可以解决CD和FTIR等现有技术的局限性。

By offering ultra-sensitive and highly reproducible structural measurements along with a full interpretation of results, Aurora TX empowers researchers to delve deeper into the characterization of nucleic acids, proteins, and other biomolecules without the need for spectroscopy expertise. With the ability to compare higher-order structures, stability profiles, and similarity profiles, Aurora TX facilitates informed decision-making across various stages of biopharmaceutical drug development, from discovery to quality control..

通过提供超灵敏和高度可重复的结构测量以及对结果的完整解释，Aurora TX使研究人员能够更深入地研究核酸，蛋白质和其他生物分子的表征，而无需光谱学专业知识。Aurora TX能够比较高阶结构，稳定性概况和相似性概况，有助于在生物制药药物开发的各个阶段（从发现到质量控制）做出明智的决策。。

Aurora TX characterizes structure and stability of RNA, proteins, and more, along with new thermal ramping capability.

Aurora TX表征RNA，蛋白质等的结构和稳定性，以及新的热爬坡能力。

One of the most noteworthy advancements of Aurora TX is its growing application in RNA analysis. With its exceptional sensitivity enabled by MMS, Aurora TX is ideal for nucleic acid characterization. Researchers can use Aurora TX to detect structural changes to RNA due to sequence modifications, formulation changes, and thermal stress.

Aurora TX最值得注意的进步之一是它在RNA分析中的应用越来越多。Aurora-TX凭借其MMS带来的非凡灵敏度，是核酸表征的理想选择。研究人员可以使用Aurora TX检测由于序列修饰，配方变化和热应激引起的RNA结构变化。

Even structural differences in the payload upon LNP encapsulation and RNA-to-LNP ratio are now measurable, all with walk-away automation..

甚至LNP封装后有效载荷的结构差异和RNA与LNP的比例现在都是可以测量的，所有这些都是通过自动控制实现的。。

The integration of thermal ramping in Aurora TX adds a new dimension to biomolecular analysis by enabling researchers to induce high-resolution temperature stress, facilitating the detection of structural changes with precision and repeatability. This feature streamlines the analysis process, saving time and resources for researchers engaged in drug discovery and development.Tom O'Lenic, CEO of RedShiftBio, commented on the launch, stating, 'Aurora TX represents a significant milestone in biophysical characterization technology.

Aurora TX中热斜坡的整合为生物分子分析增加了一个新的维度，使研究人员能够诱导高分辨率的温度应力，从而有助于精确和可重复地检测结构变化。此功能简化了分析过程，为从事药物发现和开发的研究人员节省了时间和资源。RedShiftBio首席执行官汤姆·奥莱尼克（TomO'Lenic）对此次发布发表评论说，“极光TX代表了生物物理表征技术的一个重要里程碑。

With its unparalleled sensitivity, precision, and versatility, Aurora TX empowers researchers to unlock deeper insights into biomolecular structures, presenting a pioneering strategy for RNA analysis and paving the way for advancements in the development of RNA and protein therapeutics.'Key features of Aurora TX include:.

凭借其无与伦比的灵敏度、精确度和多功能性，Aurora TX使研究人员能够对生物分子结构产生更深入的见解，为RNA分析提供了开创性的策略，并为RNA和蛋白质疗法的发展铺平了道路。”Aurora TX的主要功能包括：。

Ultra-sensitive and highly reproducible structural measurements

超灵敏和高度可重复的结构测量

Wide applicability across many therapeutic modalities

广泛适用于多种治疗方式

Thermal ramping capability for controlled temperature stress/stability assessments

受控温度应力/稳定性评估的热斜坡能力

Walk-away automation with multiple measurements in a single analysis

在一次分析中通过多次测量实现自动检测

Robust delta software for simplified data collection and interpretation

用于简化数据收集和解释的健壮delta软件

New, streamlined optional buffer station that enhances throughput by integrating up to 8 buffers directly into the system during analysis

新的、优化的可选缓冲站，通过在分析过程中将多达8个缓冲区直接集成到系统中来提高吞吐量

For more information about Aurora TX and RedShiftBio's innovative solutions, visit www.redshiftbio.com/products/aurora-txAbout RedShift BioAnalyticsRedShiftBio® is a forward-thinking technology company providing novel life science analytical platforms, reagents, software, and services to leading biopharmaceutical companies and research laboratories.

有关Aurora TX和RedShiftBio创新解决方案的更多信息，请访问www.RedShiftBio.com/products/Aurora-txAbout RedShift BioAnalyticsRedShiftBio®是一家前瞻性的技术公司，为领先的生物制药公司和研究实验室提供新颖的生命科学分析平台、试剂、软件和服务。

The company has developed a powerful new analytical technique, Microfluidic Modulation Spectroscopy (MMS), that provides in-depth biomolecule structural information in a single automated analysis. RedShiftBio also offers the HaLCon Analyzer, a fit-for-purpose protein analyzer designed to provide easy and accurate protein titer measurements at the point of need.

该公司开发了一种功能强大的新分析技术，微流体调制光谱（MMS），可在单个自动分析中提供深入的生物分子结构信息。RedShiftBio还提供HaLCon分析仪，这是一种适合用途的蛋白质分析仪，旨在根据需要提供简单准确的蛋白质滴度测量。

RedShiftBio is headquartered in Boxborough, Massachusetts.For further information, please contact:Marisa Pisani, mpisani@redshiftbio.comSOURCE RedShift BioAnalytics.

RedShiftBio总部位于马萨诸塞州的Boxborough。欲了解更多信息，请联系：Marisa Pisani，mpisani@redshiftbio.comSOURCE红移生物分析。