AbstractOne Health is a recognition of the shared environment inhabited by humans, animals and plants, and the impact of their interactions on the health of all organisms. The COVID-19 pandemic highlighted the need for a framework of pathogen surveillance in a tractable One Health paradigm to allow timely detection and response to threats to human and animal health.

摘要一种健康是对人类，动物和植物共同居住的环境及其相互作用对所有生物体健康的影响的认识。新型冠状病毒肺炎大流行强调需要一个易于处理的单一健康模式的病原体监测框架，以便及时发现和应对对人类和动物健康的威胁。

We present case studies centered around the recent global approach to tackle antimicrobial resistance and the current interest in wastewater testing, with the concept of “one sample many analyses” to be further explored as the most appropriate means of initiating this endeavor..

我们目前的案例研究围绕最近的全球方法来解决抗菌素耐药性和目前对废水检测的兴趣，其中“一个样本多个分析”的概念将被进一步探索，作为启动这项工作的最合适手段。。

Why One Health and why now?The COVID-19 pandemic has underscored the need to strengthen national surveillance systems to protect a globally connected world1. Pathogen surveillance is essential for early detection, risk assessment, preparedness, and the effective management of zoonotic diseases and pandemic threats and is a critical component of global efforts to safeguard public health and prevent the escalation of various infectious disease outbreaks.

为什么是一种健康，为什么是现在？新型冠状病毒-19大流行强调需要加强国家监测系统，以保护一个全球互联的世界1。病原体监测对于早期发现，风险评估，防范和有效管理人畜共患疾病和大流行威胁至关重要，是全球保护公共卫生和防止各种传染病疫情升级努力的关键组成部分。

Pandemics have disrupted societies and impacted public health throughout human history2, and, yet, despite the recommendations of many expert groups, public health surveillance systems have not yet improved to the point where emerging infectious threats can be better anticipated and detected earlier3.

。

Globally, existing pathogen surveillance systems face various challenges such as global health security gaps, underreporting and delays in reporting, both coupled to fragmented and incomplete surveillance data. A lack of coordination, and inadequate laboratory capacity within countries and across borders may also impede timely responses to various emerging pathogens.

在全球范围内，现有的病原体监测系统面临各种挑战，例如全球健康安全差距，报告不足和报告延迟，再加上监测数据零散和不完整。国家内部和跨境缺乏协调以及实验室能力不足也可能阻碍对各种新出现的病原体的及时反应。

The limitations of existing surveillance systems have been exposed, particularly when dealing with novel pathogens or pathogens whose geographic range has extended into a new region3.These deficiencies have underlined the critical importance of the One Health (OH) concept to tackle emerging disease threats.

现有监测系统的局限性已经暴露出来，特别是在处理新病原体或地理范围已扩展到新区域的病原体时。这些缺陷突出了“一个健康”（OH）概念对应对新出现的疾病威胁的至关重要。

Factors including increased travel4, trade5, intensive farming practices6 and climate change7, may amplify risks associated with the emergence of various pathogens in humans. This is particularly true of zoonotic pathogens, and the potential for humans to come into direct contact with these organisms from various sources.

包括增加旅行4、贸易5、集约农业实践6和气候变化7在内的因素可能会放大与人类各种病原体出现相关的风险。人畜共患病原体尤其如此，人类有可能从各种来源直接接触这些生物。

The primary tenet to the OH concept i.

OH概念i的主要宗旨。

ReferencesWorsley-Tonks, K. E. L. et al. Strengthening global health security by improving disease surveillance in remote rural areas of low-income and middle-income countries. Lancet Glob. Health 10, e579–e584 (2022).Morens, D. M., Daszak, P., Markel, H. & Taubenberger, J. K. Pandemic COVID-19 joins history’s pandemic legion mBio 11, e00812–20 (2020).Gardy, J.

参考文献Worsley-Tonks，K.E.L.等人，《通过改进低收入和中等收入国家偏远农村地区的疾病监测来加强全球卫生安全》。柳叶刀球。健康10，e579–e584（2022）。Morens，D.M.，Daszak，P.，Markel，H。＆Taubenberger，J.K。大流行性新型冠状病毒-19加入历史大流行军团mBio 11，e00812-20（2020）。Gardy，J。

L. & Loman, N. J. Towards a genomics-informed, real-time, global pathogen surveillance system. Nat. Rev. Genet. 19, 9–20 (2018).Findlater, A. & Bogoch, I. I. Human mobility and the global spread of infectious diseases: a focus on air travel. Trends in Parasitol. 34, 772–783 (2018).Jones, K. E. et al.

五十、 ＆Loman，N.J。建立基因组学信息，实时，全球病原体监测系统。Genet自然Rev。19,9-20（2018）。Findlater，A。＆Bogoch，I.I。人类流动性和传染病的全球传播：关注航空旅行。寄生虫的趋势。34772-783（2018）。Jones，K.E.等人。

Global trends in emerging infectious diseases. Nature 451, 990–993 (2008).Article .

新兴传染病的全球趋势。自然451990-993（2008）。文章。

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Jones, B. A. et al. Zoonosis emergence linked to agricultural intensification and environmental change. Proc. Natl Acad. Sci. USA 110, 8399–8404 (2013).Article

Jones，B.A.等人。人畜共患病的出现与农业集约化和环境变化有关。程序。国家科学院。科学。美国1108399–8404（2013）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Mora, C. et al. Over half of known human pathogenic diseases can be aggravated by climate change. Nat. Clim. Chang. 12, 869–875 (2022).Ruckert, A., Zinszer, K., Zarowsky, C., Labonté, R. & Carabin, H. What role for one health in the COVID-19 pandemic? Can. J. Public Health 111, 641–644 (2020).El Zowalaty, M.

Mora，C.等人。气候变化会加剧一半以上已知的人类致病性疾病。纳特·克莱姆。常。12869-875（2022）。Ruckert，A.，Zinszer，K.，Zarowsky，C.，Labonté，R。＆Carabin，H。一种健康在新冠肺炎大流行中的作用是什么？可以。J、 公共卫生111641-644（2020）。El Zowalaty，M。

E. & Järhult, J. D. From SARS to COVID-19: a previously unknown SARS- related coronavirus (SARS-CoV-2) of pandemic potential infecting humans—call for a one health approach. One Health 9, 100124 (2020).Aarestrup F. M., B. M. K. M. Pandemics: One health preparedness for the next. Lancet. Reg. Health Eur.

E、 。One Health 9100124（2020）。Aarestrup F.M.，B.M.K.M.流行病：为下一个做好健康准备。柳叶刀。注册健康欧元。

9, 100210 (2021).World Health Organisastion. Memorandum of Understanding between FAO and OIE and WHO and UNEP Regarding Cooperation to Combat Health Risks at the Animal-Human¬-Ecosystems Interface in the Context of the ‘One Health’ Approach and Including Antimicrobial Resistance. 1–8 https://www.woah.org/app/uploads/2024/03/one-health-mou.pdf (2022).Miller, S.

9100210（2021）。世界卫生组织。粮农组织和世界动物卫生组织以及世界卫生组织和环境署之间关于在“一个健康”方法的背景下合作应对动物-人类-生态系统界面的健康风险并包括抗菌素耐药性的谅解备忘录。1–8https://www.woah.org/app/uploads/2024/03/one-health-mou.pdf（2022年）。米勒，S。

A., Ferreira, J. P. & Lejeune, J. T. Antimicrobial use and resistance in plant agriculture: a One Health perspective. Agriculture 12, 289 (2022).McEwen, S. A. & Collignon, P. J. Antimicrobial resistance: a one health perspective. Microbiol. Spectr. 6, https://doi.org/10.1128/microbiolspec.ARBA-0009-2017 (2018).World Health Organisation.

A、 ，Ferreira，J。P。和Lejeune，J。T。植物农业中抗菌剂的使用和耐药性：一个健康的观点。农业12289（2022）。McEwen，S.A。和Collignon，P.J。抗菌药物耐药性：一个健康的观点。微生物。光谱。6、，https://doi.org/10.1128/microbiolspec.ARBA-0009-2017（2018年）。世界卫生组织。

Global Action Plan on Antimicrobial Resistance. 1–28 https://www.who.int/publications/i/item/9789241509763 (2015).World Health Organisation. WHO Implementation Handbook for National Action Plans on Antimicrobial Resistance: Guidance for the Human Health Sector. 1–67 https://www.who.int/publications/i/item/9789240041981 (2022).FAO UNEP WHO & WOAH.

全球抗菌素耐药性行动计划。1–28https://www.who.int/publications/i/item/9789241509763（2015年）。世界卫生组织。世卫组织抗菌药物耐药性国家行动计划实施手册：人类卫生部门指南。1–67https://www.who.int/publications/i/item/9789240041981（2022年）。粮农组织、联合国环境规划署、世界卫生组织和世界卫生组织。

One Health Joint Plan of Action, 2022–2026. One Health Joint Plan of Action, 2022–2026 (FAO; UNEP; WHO; World Organisa.

。2022-2026年一项卫生联合行动计划（粮农组织；环境署；世卫组织；世界组织）。

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Costello, M. J. & Read, P. Toxicity of sewage sludge to marine organisms: a review. Mar. Environ. Res 37, 23–46 (1994).Article

Costello，M.J。＆Read，P。污水污泥对海洋生物的毒性：综述。Mar.Environ公司。第37、23-46号决议（1994年）。文章

Google Scholar

谷歌学者

Jarvie, H. P., Neal, C. & Withers, P. J. A. Sewage-effluent phosphorus: a greater risk to river eutrophication than agricultural phosphorus? Sci. Total Environ. 360, 246–253 (2006).Article

Jarvie，H.P.，Neal，C.＆Withers，P.J.A.污水磷：河流富营养化的风险比农业磷更大？科学。总环境。360246-253（2006）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Kang, H.-J. et al. Occurrence of microplastics in municipal sewage treatment plants: a review. Environ. Anal. Health Toxicol. 33, e2018013–0 (2018).Article

Kang，H.-J.等人。城市污水处理厂中微塑料的出现：综述。环境。肛门。健康毒理学。33，e2018013-0（2018）。文章

Google Scholar

谷歌学者

Rolsky, C., Kelkar, V., Driver, E. & Halden, R. U. Municipal sewage sludge as a source of microplastics in the environment. Curr. Opin. Environ. Sci. Health 14, 16–22 (2020).Article

Rolsky，C.，Kelkar，V.，Driver，E.＆Halden，R.U。城市污水污泥是环境中微塑料的来源。货币。奥平。环境。科学。健康14,16-22（2020）。文章

Google Scholar

谷歌学者

Walker, D. I. et al. A critical review of microbiological colonisation of Nano- and Microplastics (NMP) and Their Significance to the food chain. https://www.food.gov.uk/research/foodborne-disease/a-critical-review-of-microbiological-colonisation-of-nano-and-microplastics-nmps-and-their-significance-to-the-food-chain (2022).Shanks, C.

Walker，D.I.等人，《纳米和微塑料（NMP）的微生物定植及其对食物链的意义的批判性评论》。https://www.food.gov.uk/research/foodborne-disease/a-critical-review-of-microbiological-colonisation-of-nano-and-microplastics-nmps-and-their-significance-to-the-food-chain（2022年）。柄，C。

et al. Comparison of the microbial community structures of untreated wastewaters from different geographic locales. Appl. Environ. Microbiol 79, 2906–2913 (2013).Article .

等。来自不同地理位置的未经处理废水的微生物群落结构的比较。应用。环境。微生物792906-2913（2013）。文章。

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Rafiee, M., Hosseini, S. A., Gholami-Borujeni, F., Hesami Arani, M. & Niknejad, H. Health risk assessment of swimming beaches microbial contamination: a case study—Mahmoudabad, Iran. Int. J. Environ. Health Res. 34, 355–366 (2022).Adriana, G.-F. et al. Risk of gastroenteritis from swimming at a wastewater-impacted tropical beach varies across localized scales.

Rafiee，M.，Hosseini，S.A.，Gholami Borujeni，F.，Hesami Arani，M。＆Niknejad，H。游泳场微生物污染的健康风险评估：伊朗马哈茂德·阿巴德的案例研究。内景J.环境。健康第34355-366号决议（2022年）。Adriana，G.-F.等人。在受废水影响的热带海滩游泳引起肠胃炎的风险因局部规模而异。

Appl. Environ. Microbiol. 89, e01033–22 (2023)..

苹果。大约。微生物。89，E01033–22（2023）。。

Google Scholar

谷歌学者

Berger, C. N. et al. Fresh fruit and vegetables as vehicles for the transmission of human pathogens. Environ. Microbiol. 12, 2385–2397 (2010).Article

Berger，C.N.等人，《新鲜水果和蔬菜作为人类病原体传播的媒介》。环境。微生物。122385-2397（2010）。文章

PubMed

PubMed

Google Scholar

谷歌学者

Samal, K., Mahapatra, S. & Hibzur Ali, M. Pharmaceutical wastewater as emerging contaminants (EC): treatment technologies, impact on environment and human health. Energy Nexus 6, 100076 (2022).Article

Samal，K.，Mahapatra，S。和Hibzur Ali，M。制药废水作为新兴污染物（EC）：处理技术，对环境和人类健康的影响。能源关系6100076（2022）。文章

CAS

中科院

Google Scholar

谷歌学者

Bisognin, R. P. et al. Potential environmental toxicity of sewage effluent with pharmaceuticals. Ecotoxicology 29, 1315–1326 (2020).Article

Bisognin，R.P.等人。含药物污水的潜在环境毒性。生态毒理学291315-1326（2020）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Gorovits, R., Sobol, I., Akama, K., Chefetz, B. & Czosnek, H. Pharmaceuticals in treated wastewater induce a stress response in tomato plants. Sci. Rep. 10, 1856 (2020).Article

Gorovits，R.，Sobol，I.，Akama，K.，Chefetz，B。＆Czosnek，H。处理过的废水中的药物在番茄植物中诱导应激反应。科学。第101856页（2020年）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Maskrey, B. H., Dean, K., Morrell, N. & Turner, A. D. A simple and rapid ultra–high-performance liquid chromatography–tandem mass spectrometry method for the quantitation of pharmaceuticals and related compounds in mussels and oysters. Environ. Toxicol. Chem. 40, 3263–3274 (2021).Article .

Maskrey，B.H.，Dean，K.，Morrell，N。和Turner，A.D。一种简单快速的超高效液相色谱-串联质谱法，用于定量贻贝和牡蛎中的药物和相关化合物。环境。毒理学。化学。403263-3274（2021）。文章。

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Paul, J. R., Trask, J. D. & Gard, S. Poliomyletic virus in urban sewage. J. Exp. Med. 71, 765–777 (1940).Article

Paul，J.R.，Trask，J.D。和Gard，S。城市污水中的脊髓灰质炎病毒。J、 实验医学71765-777（1940）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

COVIDPoops19. Summary of Global SARS-CoV-2 Wastewater Monitoring Efforts By UC Merced Researchers. https://www.arcgis.com/apps/dashboards/c778145ea5bb4daeb58d31afee389082 (2023).Diamond, M. B. et al. Wastewater surveillance of pathogens can inform public health responses. Nat. Med. 28, 1992–1995 (2022).European Union.

COVIDPoops19。UC Merced研究人员对全球SARS-CoV-2废水监测工作的总结。https://www.arcgis.com/apps/dashboards/c778145ea5bb4daeb58d31afee389082（2023年）。Diamond，M.B.等人。对病原体的废水监测可以为公共卫生反应提供信息。《自然医学》281992-1995（2022）。欧盟。

Commission recommendation (EU) 2021/472 of 17 March 2021 on a common approach to establish a systematic surveillance of SARS-CoV-2 and its variants in wastewaters in the EU. EUR-Lex 98, 3–8 (2021).HM UK Government. Policy Paper—UK Biological Security Strategy. https://www.gov.uk/government/publications/uk-biological-security-strategy/uk-biological-security-strategy-html (2023).G7 Health Ministers.

2021年3月17日的委员会建议（欧盟）2021/472，关于在欧盟建立对废水中SARS-CoV-2及其变体的系统监测的共同方法。EUR Lex 98，3–8（2021）。英国政府。政策文件英国生物安全战略。https://www.gov.uk/government/publications/uk-biological-security-strategy/uk-biological-security-strategy-html（2023年）。七国集团卫生部长。

G7 Health Ministers’ Communiqué 20th May 2022. https://www.g7germany.de/resource/blob/974430/2042058/5651daa321517b089cdccfaffd1e37a1/2022-05-20-g7-health-ministers-communique-data.pdf (2022).Morvan, M. et al. An analysis of 45 large-scale wastewater sites in England to estimate SARS-CoV-2 community prevalence.

2022年5月20日，七国集团卫生部长公报。https://www.g7germany.de/resource/blob/974430/2042058/5651daa321517b089cdccfaffd1e37a1/2022-05-20-g7-health-ministers-communique-data.pdf（2022年）。Morvan，M.等人。对英格兰45个大型废水场地的分析，以估计SARS-CoV-2社区流行率。

Nat. Commun. 13, 4313 (2022).Article .

Nat.普通。134313（2022）。文章。

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Brunner, F. S. et al. Utility of wastewater genomic surveillance compared to clinical surveillance to track the spread of the SARS-CoV-2 Omicron variant across England. Water Res. 247, 120804 (2023).Article

Brunner，F.S.等人。与临床监测相比，废水基因组监测在追踪SARS-CoV-2 Omicron变异在英格兰的传播方面的实用性。。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Treagus, S. et al. Metabarcoding of hepatitis E virus genotype 3 and norovirus GII from wastewater samples in England using nanopore sequencing. Food Environ. Virol. 15, 292–306 (2023).Article

Treagus，S.等人。使用纳米孔测序对英格兰废水样品中戊型肝炎病毒基因型3和诺如病毒GII进行元条形码编码。食品环境。维罗尔。15292-306（2023）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Holton, E. & Kasprzyk-Hordern, B. Multiresidue antibiotic-metabolite quantification method using ultra-performance liquid chromatography coupled with tandem mass spectrometry for environmental and public exposure estimation. Anal. Bioanal. Chem. 413, 5901–5920 (2021).Article

Holton，E。＆Kasprzyk-Hordern，B。使用超高效液相色谱与串联质谱联用的多残留抗生素代谢物定量方法，用于环境和公众暴露估计。肛门。生物醛。化学。4135901–5920（2021）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Ceolotto, N. et al. A new wastewater-based epidemiology workflow to estimate community wide non-communicable disease prevalence using pharmaceutical proxy data. J. Hazard Mater. 461, 132645 (2024).Article

Ceolotto，N。等人。一种新的基于废水的流行病学工作流程，用于使用药物替代数据估计社区范围内的非传染性疾病患病率。J、 危险物质。461132645（2024）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Baker, D. R. & Kasprzyk-Hordern, B. Multi-residue analysis of drugs of abuse in wastewater and surface water by solid-phase extraction and liquid chromatography–positive electrospray ionisation tandem mass spectrometry. J. Chromatogr. A 1218, 1620–1631 (2011).Article

Baker，D.R。＆Kasprzyk-Hordern，B。通过固相萃取和液相色谱-正电喷雾电离串联质谱法对废水和地表水中滥用药物进行多残留分析。J、 色谱仪。12181620–1631（2011）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Kasprzyk-Hordern, B. et al. Wastewater-based epidemiology for comprehensive community health diagnostics in a national surveillance study: mining biochemical markers in wastewater. J. Hazard Mater. 450, 130989 (2023).Article

Kasprzyk-Hordern，B.等人，《国家监测研究中基于废水的综合社区健康诊断流行病学：在废水中挖掘生化标记》。J、 危险物质。450130989（2023）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

WHO. A Tripartite Guide to Addressing Zoonotic Diseases in Countries Taking a Multisectoral. 1–16 https://www.who.int/publications/i/item/9789241514934 (2019).Kelly, T. R. et al. Implementing One Health approaches to confront emerging and re-emerging zoonotic disease threats: lessons from PREDICT.

谁。多部门国家应对人畜共患疾病的三方指南。1–16https://www.who.int/publications/i/item/9789241514934（2019年）。Kelly，T.R.等人，《实施一种健康方法来应对新出现和再次出现的人畜共患疾病威胁：预测的教训》。

One Health Outlook 2, 1 (2020).Article .

一个健康展望2,1（2020）。文章。

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Environment Agency & Cefas. Shellfish as Bioindicator for Coastal Antimicrobial Resistance - Summary. 1–51 https://assets.publishing.service.gov.uk/media/6540c73546532b000d67f5bb/Shellfish_as_bioindicators_for_coastal_antimicrobial_resistance_-_report.pdf (2023).Littlefair, J. E. et al.

环境署和Cefas。贝类作为沿海抗菌药物耐药性的生物指示物-摘要。1–51https://assets.publishing.service.gov.uk/media/6540c73546532b000d67f5bb/Shellfish_as_bioindicators_for_coastal_antimicrobial_resistance_-_report.pdf（2023年）。Littlefair，J.E。等人。

Air-quality networks collect environmental DNA with the potential to measure biodiversity at continental scales. Curr. Biol. 33, R426–R428 (2023).Article .

空气质量网络收集环境DNA，有可能在大陆范围内衡量生物多样性。货币。生物学33，R426–R428（2023）。文章。

PubMed

PubMed

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谷歌学者

O’Brien, E. & Xagoraraki, I. A water-focused one-health approach for early detection and prevention of viral outbreaks. One Health 7, 100094 (2019).Montgomery, D. R., Rabinowitz, P., Sipos, Y. & Wheat, E. E. Soil health: a common focus for one health and planetary health interventions.

O'Brien，E。＆Xagoraki，I。一种以水为中心的单一健康方法，用于早期发现和预防病毒爆发。One Health 7100094（2019）。Montgomery，D.R.，Rabinowitz，P.，Sipos，Y。和Wheat，E.E。土壤健康：一个健康和行星健康干预的共同焦点。

One Health 18, 100673 (2024).Ko, K. K. K., Chng, K. R. & Nagarajan, N. Metagenomics-enabled microbial surveillance. Nat. Microbiol. 7, 486–496 (2022).Article .

One Health 18100673（2024）。Ko，K.K.K.，Chng，K.R。＆Nagarajan，N。宏基因组学使微生物监测成为可能。。7486-496（2022）。文章。

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Stentiford, G. D. et al. Sustainable aquaculture through the one health lens. Nat. Food 1, 468–474 (2020).Article

Stentiford，G.D.等人，《通过一个健康视角实现可持续水产养殖》。《国家食品》1468-474（2020）。文章

CAS

中科院

PubMed

PubMed

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谷歌学者

Mackenzie, J. S., McKinnon, M. & Jeggo, M. In Confronting Emerging Zoonoses: The One Health Paradigm (eds Yamada, A. et al.) 163–189 (Springer Japan, 2014).Download referencesAcknowledgementsFunded by His Majesty’s Treasury Shared Outcomes Fund Pathogen surveillance in Agriculture, Food and the Environment (PATH-SAFE) programme.Author informationAuthors and AffiliationsCentre for Environment Fisheries and Aquaculture Science, Weymouth, Dorset, UKRichard Hill, Grant G.

Mackenzie，J.S.，McKinnon，M。＆Jeggo，M。在《对抗新出现的人畜共患病：一种健康范式》（eds Yamada，A。等人）163-189（Springer Japan，2014）。下载参考文献致谢由英国财政部共享成果基金农业、食品和环境病原体监测（PATH-SAFE）计划资助。作者信息环境渔业和水产养殖科学的作者和附属机构，韦茅斯，多塞特，UKRichard Hill，Grant G。

Stentiford, David I. Walker, Craig Baker-Austin, Georgia Ward, Benjamin H. Maskrey, Ronny van Aerle, Edmund Peeler & David BassCentre for Environment Fisheries and Aquaculture Science, Genomics Facility, Exeter, Devon, UKRichard HillWorldFish, Jalan Batu Maung, 11960, Bayan Lepas, Penang, MalaysiaDavid Verner-JeffreysAuthorsRichard HillView author publicationsYou can also search for this author in.

Stentiford，David I.Walker，Craig Baker Austin，Georgia Ward，Benjamin H.Maskrey，Ronny van Aerle，Edmund Peeler＆David Bass环境渔业和水产养殖科学中心，基因组学设施，德文郡埃克塞特，UKRichard HillWorldFish，Jalan Batu Maung，11960，马来西亚槟城巴彦Lepas Vid Verner JeffreysAuthorsRichard HillView作者出版物您也可以在中搜索这位作者。

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PubMed Google ScholarContributionsConceptualisation of the manuscript: Stentiford, G., Bass, D., Baker-Austin, C., Walker, D. and Hill, R. Original draft written by: Hill, R., Baker-Austin, C, Walker, D., Bass, D., Maskrey, B., van Aerle, R., Ward, G., Verner-Jeffreys, D., Peeler, E and Stentiford, G.

PubMed谷歌学术贡献手稿的概念化：Stentiford，G.，Bass，D.，Baker-Austin，C.，Walker，D。和Hill，R。原稿作者：Hill，R.，Baker-Austin，C，Walker，D.，Bass，D.，Maskrey，B.，van Aerle，R.，Ward，G.，Verner-Jeffreys，D.，Peeler，E和Stentiford，G。

Manuscript review and editing: Baker-Austin, C, Walker, D., Hill, R., Bass, D. and van Aerle, R. Figures provided by: Baker-Austin, C, Walker, D., Bass, D., Maskrey, B., van Aerle, R. and Stentiford, G.Corresponding authorCorrespondence to.

手稿审查和编辑：Baker Austin，C，Walker，D.，Hill，R.，Bass，D。和van Aerle，R。数字由Baker Austin，C，Walker，D.，Bass，D.，Maskrey，B.，van Aerle，R。和Stentiford，G。相应的作者。

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Nature Communications thanks Marguerite Pappaioanou and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

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Reprints and permissionsAbout this articleCite this articleHill, R., Stentiford, G.G., Walker, D.I. et al. Realising a global One Health disease surveillance approach: insights from wastewater and beyond.

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Nat Commun 15, 5324 (2024). https://doi.org/10.1038/s41467-024-49417-4Download citationReceived: 01 September 2023Accepted: 31 May 2024Published: 22 June 2024DOI: https://doi.org/10.1038/s41467-024-49417-4Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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