AbstractModerately elevated albuminuria (30–300 mg/g) is a marker of renal dysfunction and a risk factor of cardiovascular disease. Additionally, several recent studies have reported a relationship between moderately elevated albuminuria and triglyceride (TG) levels. Therefore, we aimed to evaluate the relationship between the urine albumin-to-creatinine ratio (UACR) and total cholesterol (TC), TG, and high-density lipoprotein C (HDL-C) levels.

摘要中度升高的白蛋白尿（30-300 mg/g）是肾功能不全的标志物，也是心血管疾病的危险因素。此外，最近的几项研究报道了中度升高的白蛋白尿与甘油三酯（TG）水平之间的关系。因此，我们旨在评估尿白蛋白与肌酐比值（UACR）与总胆固醇（TC），TG和高密度脂蛋白C（HDL-C）水平之间的关系。

We analyzed data from 19,340 patients from the 2011–2014 and 2019–2020 from the Korea National Health and Nutrition Examination Surveys. Multivariate linear regression analysis showed that the UACR was positively associated with TC and TG levels and negatively associated with HDL-C levels in both Korean women and men.

我们分析了韩国国家健康与营养检查调查中2011-2014年和2019-2020年19340名患者的数据。多元线性回归分析显示，韩国女性和男性的UACR与TC和TG水平呈正相关，与HDL-C水平呈负相关。

These results were reanalyzed according to the degree of proteinuria (normal, moderately elevated albuminuria, and severely elevated albuminuria (≥ 300 mg/g)). We found a positive relationship between UACR and TC and TG levels, but a negative association with HDL-C levels, except for TC (moderately elevated albuminuria) and HDL-C (moderately elevated albuminuria) in Korean men and TC (severely elevated albuminuria), TG (severely elevated albuminuria), and HDL-C (normal range albuminuria) in Korean women.

根据蛋白尿程度（正常，中度升高的蛋白尿和严重升高的蛋白尿（≥300 mg/g））重新分析这些结果。我们发现UACR与TC和TG水平呈正相关，但与HDL-C水平呈负相关，除了韩国男性的TC（中度升高的蛋白尿）和HDL-C（中度升高的蛋白尿）和TC（严重升高的蛋白尿），TG（严重升高的蛋白尿）和HDL-C（正常范围的蛋白尿）在韩国女性中。

The correlation between albuminuria and lipid profiles became more evident as albuminuria shift from normal to the severely elevated albuminuria. Thus our multivariate linear regression analysis showed that lipid profiles (TG, TC, and HDL-C levels) were associated with the UACR..

。。

IntroductionAn elevated urine albumin creatinine ratio (UACR) is a marker of renal dysfunction and an independent predictor of cardiovascular disease1,2. In addition, several studies have shown that moderately increased albuminuria (UACR < 30 mg/g) within the accepted normal range is associated with higher cardiovascular morbidity and mortality, even in the general population3,4.

引言尿白蛋白-肌酐比值（UACR）升高是肾功能不全的标志物，也是心血管疾病的独立预测因子1,2。此外，一些研究表明，即使在普通人群中，在可接受的正常范围内适度增加的白蛋白尿（UACR<30 mg/g）也与较高的心血管发病率和死亡率相关3,4。

Cardiovascular disease (CVD) is a broad-spectrum disease associated with numerous pathophysiological mechanisms such as inflammation5, fatty acid metabolic processes, and cholesterol metabolic process6.Several recent studies have also shown a correlation between triglycerides (TGs) and UACR7,8,9. A Japanese cohort study showed that increased TG levels were an independent risk factor for the development of proteinuria in both men (relative risk [RR], 1.032) and women (RR 1.007)7.

心血管疾病（CVD）是一种广谱疾病，与许多病理生理机制有关，如炎症5，脂肪酸代谢过程和胆固醇代谢过程6。最近的一些研究也显示甘油三酯（TGs）与UACR7,8,9之间存在相关性。一项日本队列研究表明，TG水平升高是男性（相对危险度（RR），1.032）和女性（RR 1.007）发生蛋白尿的独立危险因素7。

The Korean National Health and Nutrition Examination Survey (KNHANES) study also showed that TG levels are correlated with the albumin-to-creatinine ratio in adults with hypertension9. The Risk Evaluation of cancers in Chinese diabetic Individuals: A longitudinal (REACTION) study also showed that higher TG levels (> 2.3 mmol/L) were associated with the UACR in both men and women8.

韩国国家健康与营养调查（KNHANES）的研究还表明，TG水平与高血压成人的白蛋白与肌酐比值相关9。。

Moreover, treatment of dyslipidemia may be beneficial in reducing albuminuria in patients with chronic kidney disease (CKD)10.Cholesterol and TG levels are influenced by several factors, such as age, sex, diet style, and sleep; therefore, large datasets are required to identify reliable and generalized associations between UACR and lipid profiles.

此外，血脂异常的治疗可能有助于减少慢性肾病（CKD）患者的蛋白尿10。胆固醇和TG水平受多种因素的影响，如年龄，性别，饮食方式和睡眠；因此，需要大量数据集来确定UACR与血脂谱之间可靠且普遍的关联。

Consequently, we performed three assessments using a nationally representative Korean dataset. First, we conducted a univariate analysis, using Pearson’s and Spearman’s correlation analyses, Followed.

因此，我们使用具有全国代表性的韩国数据集进行了三次评估。首先，我们使用Pearson和Spearman的相关分析进行了单变量分析。

Data availability

数据可用性

This study analyzed the data obtained from the KNHANES. The KNHANES database contains publicly available data (https://knhanes.kdca.go.kr/knhanes/sub03/sub03_02_05.do).

这项研究分析了从KNHANES获得的数据。KNHANES数据库包含公开可用的数据(https://knhanes.kdca.go.kr/knhanes/sub03/sub03_02_05.do)。

ReferencesGerstein, H. C. et al. Albuminuria and risk of cardiovascular events, death, and heart failure in diabetic and nondiabetic individuals. JAMA 286, 421–426. https://doi.org/10.1001/jama.286.4.421 (2001).Article

参考文献Gerstein，H.C。等人。糖尿病和非糖尿病患者的白蛋白尿和心血管事件，死亡和心力衰竭的风险。JAMA 286421-426。https://doi.org/10.1001/jama.286.4.421（2001年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Stevens, P. E. & Levin, A. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: Improving global outcomes 2012 clinical practice guideline. Ann. Intern. Med. 158, 825–830. https://doi.org/10.7326/0003-4819-158-11-201306040-00007 (2013).Article

Stevens，P。E。和Levin，A。慢性肾脏病的评估和管理：肾脏疾病概要：改善2012年全球结果临床实践指南。安，实习生。医学158825-830。https://doi.org/10.7326/0003-4819-158-11-201306040-00007（2013年）。文章

PubMed

PubMed

Google Scholar

谷歌学者

Mogensen, C. E. Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N. Engl. J. Med. 310, 356–360. https://doi.org/10.1056/nejm198402093100605 (1984).Article

微量白蛋白尿可预测成熟型糖尿病的临床蛋白尿和早期死亡率。N、 英语。J、 医学310356-360。https://doi.org/10.1056/nejm198402093100605（1984年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Kim, Y. J., Hwang, S. W., Lee, T., Lee, J. Y. & Uh, Y. Association between urinary albumin creatinine ratio and cardiovascular disease. PLoS One 18, e0283083. https://doi.org/10.1371/journal.pone.0283083 (2023).Article

Kim，Y.J.，Hwang，S.W.，Lee，T.，Lee，J.Y。＆Uh，Y。尿白蛋白-肌酐比率与心血管疾病之间的关联。PLoS One 18，e0283083。https://doi.org/10.1371/journal.pone.0283083。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Lee, T. et al. Identification of cardiovascular disease-related genes based on the co-expression network analysis of genome-wide blood transcriptome. Cells 11, 2867. https://doi.org/10.3390/cells11182867 (2022).Article

Lee，T.等人。基于全基因组血液转录组的共表达网络分析鉴定心血管疾病相关基因。细胞112867。https://doi.org/10.3390/cells11182867（2022年）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Koplev, S. et al. A mechanistic framework for cardiometabolic and coronary artery diseases. Nat. Cardiovasc. Res. 1, 85–100. https://doi.org/10.1038/s44161-021-00009-1 (2022).Article

Koplev，S.等人。心脏代谢和冠状动脉疾病的机制框架。自然心血管。第1、85-100号决议。https://doi.org/10.1038/s44161-021-00009-1（2022年）。文章

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Tozawa, M. et al. Triglyceride, but not total cholesterol or low-density lipoprotein cholesterol levels, predict development of proteinuria. Kidney Int. 62, 1743–1749. https://doi.org/10.1046/j.1523-1755.2002.00626.x (2002).Article

Tozawa，M.等人，《甘油三酯（而非总胆固醇或低密度脂蛋白胆固醇水平）可预测蛋白尿的发展》。肾脏杂志621743-1749。https://doi.org/10.1046/j.1523-1755.2002.00626.x。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Wang, Y. X. et al. Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to creatinine ratio in the general population of China: a report from the REACTION study. Cardiovasc. Diabetol. 18, 57. https://doi.org/10.1186/s12933-019-0863-8 (2019).Article .

Wang，Y.X.等人。反应研究的一份报告显示，在中国普通人群中，甘油三酯升高而非其他脂质参数升高与尿白蛋白与肌酐比值升高有关。心血管。糖尿病。18，57。https://doi.org/10.1186/s12933-019-0863-8（2019年）。文章。

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Lee, S. H. et al. Relationship between dyslipidemia and albuminuria in hypertensive adults: A nationwide population-based study. Medicine (Baltimore) 95, e3224. https://doi.org/10.1097/md.0000000000003224 (2016).Article

Lee，S.H.等人。高血压成人血脂异常与蛋白尿之间的关系：一项全国范围的基于人群的研究。医学（巴尔的摩）95，e3224。https://doi.org/10.1097/md.0000000000003224（2016年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Zhang, Z., Wu, P., Zhang, J., Wang, S. & Zhang, G. The effect of statins on microalbuminuria, proteinuria, progression of kidney function, and all-cause mortality in patients with non-end stage chronic kidney disease: A meta-analysis. Pharmacol. Res. 105, 74–83. https://doi.org/10.1016/j.phrs.2016.01.005 (2016).Article .

Zhang，Z.，Wu，P.，Zhang，J.，Wang，S。＆Zhang，G。他汀类药物对非终末期慢性肾病患者微量白蛋白尿，蛋白尿，肾功能进展和全因死亡率的影响：荟萃分析。药理学。第105、74-83号决议。https://doi.org/10.1016/j.phrs.2016.01.005（2016年）。文章。

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Tien, K. J., Tu, S. T., Chen, H. C., Hsiao, J. Y. & Hsieh, M. C. Triglycerides are independently associated with albuminuria in Taiwanese Type 2 diabetic patients. J. Endocrinol. Investig. 35, 800–803. https://doi.org/10.3275/8060 (2012).Article

Tien，K.J.，Tu，S.T.，Chen，H.C.，Hsiao，J.Y。和Hsieh，M.C。甘油三酯与台湾2型糖尿病患者的蛋白尿独立相关。J、 内分泌。调查。35800–803。https://doi.org/10.3275/8060（2012年）。文章

CAS

中科院

Google Scholar

谷歌学者

Tian, Y. et al. Association between the triglyceride-glucose index and albuminuria in hypertensive individuals. Clin. Exp. Hypertens. 45, 2150204. https://doi.org/10.1080/10641963.2022.2150204 (2023).Article

Tian，Y.等人。高血压患者甘油三酯-葡萄糖指数与蛋白尿之间的关系。临床。实验高血压。452150204。https://doi.org/10.1080/10641963.2022.2150204。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Moorhead, J. F., Chan, M. K., El-Nahas, M. & Varghese, Z. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease. Lancet 2, 1309–1311. https://doi.org/10.1016/s0140-6736(82)91513-6 (1982).Article

Moorhead，J.F.，Chan，M.K.，El Nahas，M。＆Varghese，Z。慢性进行性肾小球和肾小管间质疾病的脂质肾毒性。柳叶刀21309-1311。https://doi.org/10.1016/s0140-6736（82）91513-6（1982）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Samuelsson, O. et al. Complex apolipoprotein B-containing lipoprotein particles are associated with a higher rate of progression of human chronic renal insufficiency. J. Am. Soc. Nephrol. 9, 1482–1488. https://doi.org/10.1681/asn.V981482 (1998).Article

Samuelsson，O。等人。含有复杂载脂蛋白B的脂蛋白颗粒与人类慢性肾功能不全的更高进展率有关。J、 美国社会肾脏病学会。91482-1488年。https://doi.org/10.1681/asn.V981482（1998年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Tan, K. et al. Hypertriglyceridaemia and vascular risk. Report of a meeting of physicians and scientists, University College London Medical School. Lancet 342, 781–787. https://doi.org/10.1016/0140-6736(93)91544-V (1993).Article

Tan，K。等人。高甘油三酯血症和血管风险。伦敦大学学院医学院医生和科学家会议的报告。柳叶刀342781-787。https://doi.org/10.1016/0140-6736（93）91544-V（1993）。文章

Google Scholar

谷歌学者

Kamgar, M. et al. Impaired fibrinolytic activity in type II diabetes: correlation with urinary albumin excretion and progression of renal disease. Kidney Int. 69, 1899–1903. https://doi.org/10.1038/sj.ki.5000355 (2006).Article

Kamgar，M.等人，《II型糖尿病纤溶活性受损：与尿白蛋白排泄和肾脏疾病进展的相关性》。肾脏Int.691899-1903。https://doi.org/10.1038/sj.ki.5000355（2006年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Guerrero-Romero, F. et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J. Clin. Endocrinol. Metab. 95, 3347–3351. https://doi.org/10.1210/jc.2010-0288 (2010).Article

Guerrero-Romero，F。等人。甘油三酯和葡萄糖的产物，一种简单的胰岛素敏感性测量方法。与正常血糖高胰岛素钳夹的比较。J、 临床。内分泌。代谢。953347-3351。https://doi.org/10.1210/jc.2010-0288（2010年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Bolton, C. H. et al. Endothelial dysfunction in chronic renal failure: Roles of lipoprotein oxidation and pro-inflammatory cytokines. Nephrol. Dial. Transplant. 16, 1189–1197. https://doi.org/10.1093/ndt/16.6.1189 (2001).Article

。肾。拨号。移植。161189-1197年。https://doi.org/10.1093/ndt/16.6.1189（2001年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Vaziri, N. D. Lipotoxicity and impaired high density lipoprotein-mediated reverse cholesterol transport in chronic kidney disease. J. Ren. Nutr. 20, S35-43. https://doi.org/10.1053/j.jrn.2010.05.010 (2010).Article

Vaziri，N.D。慢性肾病中脂毒性和高密度脂蛋白介导的胆固醇逆向转运受损。J、 任。营养。20，S35-43。https://doi.org/10.1053/j.jrn.2010.05.010（2010年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Sun, X. et al. Association of serum high-density lipoprotein cholesterol with microalbuminuria in type 2 diabetes patients. Lipids Health Dis. 17, 229. https://doi.org/10.1186/s12944-018-0878-2 (2018).Article

Sun，X。等人。2型糖尿病患者血清高密度脂蛋白胆固醇与微量白蛋白尿的关系。脂质健康疾病。17229页。https://doi.org/10.1186/s12944-018-0878-2（2018年）。文章

CAS

中科院

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Madison, J. R. et al. Proteinuria and risk for stroke and coronary heart disease during 27 years of follow-up: The Honolulu heart program. Arch. Intern. Med. 166, 884–889. https://doi.org/10.1001/archinte.166.8.884 (2006).Article

麦迪逊，J.R.等人，《27年随访期间蛋白尿与中风和冠心病风险：火奴鲁鲁心脏计划》。拱门。实习生。医学166884-889。https://doi.org/10.1001/archinte.166.8.884（2006年）。文章

ADS

广告

PubMed

PubMed

Google Scholar

谷歌学者

Remuzzi, G., Ruggenenti, P. & Perico, N. Chronic renal diseases: Renoprotective benefits of renin-angiotensin system inhibition. Ann. Intern. Med. 136, 604–615. https://doi.org/10.7326/0003-4819-136-8-200204160-00010 (2002).Article

Remuzzi，G.，Ruggenenti，P。＆Perico，N。慢性肾脏疾病：肾素-血管紧张素系统抑制的肾脏保护作用。安，实习生。医学136604-615。https://doi.org/10.7326/0003-4819-136-8-200204160-00010。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Jensen, J. S. Renal and systemic transvascular albumin leakage in severe atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 15, 1324–1329. https://doi.org/10.1161/01.atv.15.9.1324 (1995).Article

Jensen，J.S。严重动脉粥样硬化中的肾脏和全身血管内白蛋白渗漏。动脉硬化。血栓。Vasc。生物学151324-1329。https://doi.org/10.1161/01.atv.15.9.1324（1995年）。文章

CAS

中科院

PubMed

PubMed

Google Scholar

谷歌学者

Paisley, K. E. et al. Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney Int. 63, 624–633. https://doi.org/10.1046/j.1523-1755.2003.00768.x (2003).Article

Paisley，K.E.等人，《无症状蛋白尿中的内皮功能障碍和炎症》。肾脏Int.63624-633。https://doi.org/10.1046/j.1523-1755.2003.00768.x。文章

PubMed

PubMed

Google Scholar

谷歌学者

Kweon, S. et al. Data resource profile: The Korea national health and nutrition examination survey (KNHANES). Int. J. Epidemiol. 43, 69–77. https://doi.org/10.1093/ije/dyt228 (2014).Article

Kweon，S.等人。数据资源概况：韩国国家健康与营养调查（KNHANES）。国际流行病学杂志。43，69-77。https://doi.org/10.1093/ije/dyt228（2014年）。文章

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Kim, Y. The Korea National Health and nutrition examination survey (KNHANES): Current status and challenges. Epidemiol. Health 36, e2014002. https://doi.org/10.4178/epih/e2014002 (2014).Article

Kim，Y。韩国国家健康与营养调查（KNHANES）：现状和挑战。流行病。健康36，e2014002。https://doi.org/10.4178/epih/e2014002（2014年）。文章

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Arnlöv, J. et al. Low-grade albuminuria and incidence of cardiovascular disease events in nonhypertensive and nondiabetic individuals: The Framingham Heart Study. Circulation 112, 969–975. https://doi.org/10.1161/circulationaha.105.538132 (2005).Article

Arnlöv，J.等人。非高血压和非糖尿病患者的低度白蛋白尿和心血管疾病事件发生率：弗雷明汉心脏研究。。https://doi.org/10.1161/circulationaha.105.538132。文章

PubMed

PubMed

Google Scholar

谷歌学者

D’Agostino, R. B. Sr. et al. General cardiovascular risk profile for use in primary care: The Framingham Heart Study. Circulation 117, 743–753. https://doi.org/10.1161/circulationaha.107.699579 (2008).Article

D'Agostino，R.B.Sr.等人，《初级保健中使用的一般心血管风险概况：弗雷明汉心脏研究》。发行量117743–753。https://doi.org/10.1161/circulationaha.107.699579（2008年）。文章

PubMed

PubMed

Google Scholar

谷歌学者

Goff, D. C. Jr. et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129, S49-73. https://doi.org/10.1161/01.cir.0000437741.48606.98 (2014).Article .

Goff，D.C.Jr.等人，2013 ACC/AHA心血管风险评估指南：美国心脏病学会/美国心脏协会实践指南特别工作组的报告。循环129，S49-73。https://doi.org/10.1161/01.cir.0000437741.48606.98（2014年）。文章。

PubMed

PubMed

Google Scholar

谷歌学者

Yadlowsky, S. et al. Clinical implications of revised pooled cohort equations for estimating atherosclerotic cardiovascular disease risk. Ann. Intern. Med. 169, 20–29. https://doi.org/10.7326/m17-3011 (2018).Article

Yadlowsky，S.等人。用于估计动脉粥样硬化性心血管疾病风险的修订汇总队列方程的临床意义。安，实习生。医学169，20-29。https://doi.org/10.7326/m17-3011（2018年）。文章

PubMed

PubMed

Google Scholar

谷歌学者

Download referencesAuthor informationAuthors and AffiliationsDepartment of Precision Medicine, Yonsei University Wonju College of Medicine, Wonju, South KoreaSang Won HwangDepartment of Family Medicine, Yonsei University Wonju College of Medicine, Wonju, South KoreaTaesic LeeDivision of Health Informatics, Institute of Global Health Care and Development, Wonju, South KoreaTaesic LeeDepartment of Laboratory Medicine, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, 26426, Republic of KoreaYoung UhDepartment of Nephrology, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, 26426, Republic of KoreaJun Young LeeTransplantation Center, Yonsei University Wonju College of Medicine, Wonju, South KoreaJun Young LeeCenter of Evidence Based Medicine, Institute of Convergence Science, Yonsei University, Seoul, South KoreaJun Young LeeAuthorsSang Won HwangView author publicationsYou can also search for this author in.

下载参考文献作者信息作者和所属机构延世大学元州医学院精准医学系，南韩元州，延世大学元州医学院家庭医学系，南韩元州，延世大学元州医学院，南韩元州，全球卫生保健与发展研究所卫生信息学系，南韩元州，延世大学元州医学院实验医学系，20 Ilsan ro，Wonju，26426，大韩民国肾脏病学系，延世大学元州医学院，20 Ilsan ro，Wonju，26426，大韩民国杨利移植中心韩国延世大学元州医学院南韩延世大学融合科学研究所循证医学中心南韩延世大学元州医学院南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩延世大学南韩医学院南韩延世大学南韩延世大学南韩医学院南韩延世大学南韩延世大学南韩延世大学南韩医学院南韩延世大学南韩延世大学南韩延世大学南韩大学南韩大学南韩延世大学南韩大学南韩延世大学南韩大学南韩医学院南韩延世大学南韩大学南韩延世大学南韩大学南韩延世大学南韩大学南韩大学南韩大学南韩大学南韩大学南。

PubMed Google ScholarTaesic LeeView author publicationsYou can also search for this author in

PubMed Google ScholarYoung UhView author publicationsYou can also search for this author in

PubMed Google ScholarYoung UhView作者出版物您也可以在

PubMed Google ScholarJun Young LeeView author publicationsYou can also search for this author in

PubMed Google ScholarJun Young LeeView作者出版物您也可以在

PubMed Google ScholarContributionsConceptualization, S.W.H. and J.Y.L.; methodology, S.W.H., T.L., Y.U. and J.Y.L.; software, S.W.H., T.L., Y.U. and J.Y.L.; validation, S.W.H., T.L., Y.U. and J.Y.L.; formal analysis, S.W.H., T.L., Y.U. and J.Y.L.; investigation, Y.U. and J.Y.L.; resources, Y.U.

PubMed谷歌学术贡献概念化，S.W.H.和J.Y.L。；方法论，S.W.H.，T.L.，Y.U.和J.Y.L。；软件，S.W.H.，T.L.，Y.U.和J.Y.L。；验证，S.W.H.，T.L.，Y.U.和J.Y.L。；形式分析，S.W.H.，T.L.，Y.U.和J.Y.L。；调查，Y.U.和J.Y.L。；资源，Y.U。

and J.Y.L.; data curation, S.W.H., T.L., Y.U. and J.Y.L.; writing—original draft preparation, S.W.H., T.L., Y.U. and J.Y.L.; writing—review and editing, S.W.H., T.L., Y.U. and J.Y.L.; visualization, S.W.H., T.L., Y.U. and J.Y.L.; supervision, Y.U. and J.Y.L.; project administration, J.Y.L.; funding acquisition, J.Y.L.

和J.Y.L。；数据管理，S.W.H.，T.L.，Y.U.和J.Y.L。；撰写原始草案准备，S.W.H.，T.L.，Y.U.和J.Y.L。；写作评论和编辑，S.W.H.，T.L.，Y.U.和J.Y.L。；。；监督，Y.U.和J.Y.L。；项目管理，J.Y.L。；资金收购，J.Y.L。

All authors have read and agreed to the published version of the manuscript.Corresponding authorsCorrespondence to.

所有作者均已阅读并同意稿件的发布版本。通讯作者通讯。

Young Uh or Jun Young Lee.Ethics declarations

Young Uh或Jun Young Lee。道德宣言

Competing interests

相互竞争的利益

The authors declare no competing interests.

作者声明没有利益冲突。

Additional informationPublisher's noteSpringer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Supplementary InformationSupplementary Information.Rights and permissions

Additional informationPublisher的noteSpringer Nature在已发布地图和机构隶属关系中的管辖权主张方面保持中立。补充信息补充信息。权限和权限

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

开放获取本文是根据知识共享署名4.0国际许可证授权的，该许可证允许以任何媒体或格式使用，共享，改编，分发和复制，只要您对原始作者和来源给予适当的信任，提供知识共享许可证的链接，并指出是否进行了更改。

The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.

本文中的图像或其他第三方材料包含在文章的知识共享许可中，除非在材料的信用额度中另有说明。如果材料未包含在文章的知识共享许可证中，并且您的预期用途未被法律法规允许或超出允许的用途，则您需要直接获得版权所有者的许可。

To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/..

要查看此许可证的副本，请访问http://creativecommons.org/licenses/by/4.0/..

Reprints and permissionsAbout this articleCite this articleHwang, S.W., Lee, T., Uh, Y. et al. Urinary albumin creatinine ratio is associated with lipid profile.

转载和许可本文引用本文Hwang，S.W.，Lee，T.，Uh，Y。等人。尿白蛋白-肌酐比率与血脂有关。

Sci Rep 14, 14870 (2024). https://doi.org/10.1038/s41598-024-65037-wDownload citationReceived: 19 October 2023Accepted: 17 June 2024Published: 27 June 2024DOI: https://doi.org/10.1038/s41598-024-65037-wShare this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

Sci Rep 1414870（2024）。https://doi.org/10.1038/s41598-024-65037-wDownload引文收到日期：2023年10月19日接受日期：2024年6月17日发布日期：2024年6月27日OI：https://doi.org/10.1038/s41598-024-65037-wShare本文与您共享以下链接的任何人都可以阅读此内容：获取可共享链接对不起，本文目前没有可共享的链接。复制到剪贴板。

Provided by the Springer Nature SharedIt content-sharing initiative

由Springer Nature SharedIt内容共享计划提供

CommentsBy submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

评论通过提交评论，您同意遵守我们的条款和社区指南。如果您发现有虐待行为或不符合我们的条款或准则，请将其标记为不合适。