BALTIMORE, Sept. 14, 2023 /PRNewswire/ -- Today the American Urological Association (AUA) released the 2023 clinical practice guideline amendment for the diagnosis and treatment of early-stage testicular cancer.

巴尔的摩，2023年9月14日/PRNewswire/-今天美国泌尿学协会（AUA）发布了2023年临床实践指南修正案，用于早期睾丸癌的诊断和治疗。

Testicular cancer is the most common solid malignancy in young males and is relatively rare, with outcomes defined by specific cancer and patient-related factors. Many men with testis cancer have low-stage disease and survival rates are high with standard therapy. A priority for those patients with low-stage disease is limiting the burden of therapy and treatment-related toxicity without compromising cancer control..

睾丸癌是年轻男性中最常见的实体恶性肿瘤，并且相对罕见，其结果由特定癌症和患者相关因素决定。许多患有睾丸癌的男性患有低阶段疾病，标准治疗的存活率很高。那些患有低度疾病的患者的首要任务是在不损害癌症控制的情况下限制治疗负担和与治疗相关的毒性。。

This guideline was reviewed through the AUA Update Literature Review (ULR) process and subsequently amended based on the availability of new literature, including:

本指南通过AUA更新文献综述（ULR）流程进行审查，随后根据新文献的可用性进行修订，包括：

New studies included to support the role of MRI in surveillance/staging of patients with germ cell tumors.

新的研究包括支持MRI在生殖细胞肿瘤患者监测/分期中的作用。

Retroperitoneal lymph node dissection added as a treatment option for patients with stage IIA or IIB seminoma with a lymph node ≤3cm.

对于淋巴结≤3cm的IIA或IIB期精原细胞瘤患者，腹膜后淋巴结清扫作为治疗选择。

Updated text to include long-term follow up for 2 cycles of etoposide and cisplatin chemotherapy without bleomycin for patients with non-seminoma germ cell tumors who have pathological stage II disease that is not pure teratoma.

更新的文本包括长期随访2个周期的依托泊苷和顺铂化疗无博来霉素的非精原细胞瘤生殖细胞肿瘤患者的病理II期疾病，不是纯粹的畸胎瘤。

New evidence added to support surveillance imaging for patients with stage I testicular cancer.

增加了新的证据来支持I期睾丸癌患者的监测成像。

Updated statement and expanded text on survivorship.

更新的声明和关于幸存者的扩展文本。

'Surveillance has become more important than ever for those with testicular cancer,' said Dr. Andrew Stephenson, Director of Urologic Oncology at Rush University Medical Center. 'Since the last testicular cancer guideline was released, the model for management has substantially changed, making an amendment like this critical to effectively treat and manage testicular cancer.'.

拉什大学医学中心泌尿肿瘤科主任安德鲁·斯蒂芬森博士说：“对于睾丸癌患者，监测变得比以往任何时候都更重要。”自从上一份睾丸癌指南发布以来，管理模式发生了实质性变化，对有效治疗和管理睾丸癌进行了这样的修改。

This amendment is an update from the 2019 guideline that originally covered the topic. It was distributed to peer reviewers of varying backgrounds as part of the AUA's extensive peer review process before being approved by the AUA Board of Directors and SUFU Executive Committee.

本修正案是最初涵盖该主题的2019年指南的更新。在获得AUA董事会和SUFU执行委员会批准之前，它被分发给不同背景的同行评审员，作为AUA广泛同行评审过程的一部分。

The full updated guideline is now available at auanet.org/TesticularCancerGuideline.

完整更新的指南现在可以在auanet.org/TesticularCancerGuideline上找到。

A summary of the Guideline also appears at:

指南摘要还显示在：

Stephenson A, Bass EB, Bixler BR, et al. Diagnosis and treatment of early-stage testicular cancer: AUA Guideline amendment 2023. J Urol. 2023;10.1097/JU.0000000000003694. https://doi.org/10.1097/JU.0000000000003698Please use this reference to cite the guideline.

Stephenson A，Bass EB，Bixler BR，et al。早期睾丸癌的诊断和治疗：AUA指南修正案2023。J Urol。2023;10.1097/JU.0000000000003694。https://doi.org/10.1097/JU.0000000000003698Please使用此参考文献引用指南。

About the American Urological Association: Founded in 1902 and headquartered near Baltimore, Maryland, the American Urological Association is a leading advocate for the specialty of urology, and has more than 23,000 members throughout the world. The AUA is a premier urologic association, providing invaluable support to the urologic community as it pursues its mission of fostering the highest standards of urologic care through education, research and the formulation of health policy..

关于美国泌尿外科协会：成立于1902年，总部设在马里兰州巴尔的摩附近，美国泌尿外科协会是泌尿外科专业的主要倡导者，拥有23000多名会员。AUA是一个重要的泌尿外科协会，为泌尿外科社区提供宝贵的支持，因为它追求通过教育，研究和制定卫生政策培养最高标准泌尿外科护理的使命。。

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SOURCE American Urological Association

资料来源美国泌尿学协会