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面神经重建治疗弛缓性面瘫的系统综述和荟萃分析

Facial nerve reconstruction for flaccid facial paralysis: A systematic review and meta-analysis

Frontiers in Oncology 等信源发布 2024-07-08 08:01

可切换为仅中文


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register hereObjectives: To determine the functional outcome after facial nerve reconstruction surgery in patients with flaccid facial paralysis.Methods: Systematic review and meta-analysis on studies reporting outcomes after direct facial nerve suture (DFS), facial nerve interpositional graft suture (FIGS), hypoglossal facial nerve suture (HFS), masseteric-facial nerve suture (MFS), and cross-face nerve suture (CFS) using were identified from PubMed/MEDLINE, Embase, Web of Science databases.

目的:确定松弛性面瘫患者面神经重建手术后的功能结果。方法:对直接面神经缝合术(DFS),面神经间置移植物缝合术(FIGS),舌下面神经缝合术(HFS),咬肌面神经缝合术(MFS)和面神经交叉缝合术(CFS)后报告结果的研究进行系统回顾和荟萃分析,使用PubMed/MEDLINE,Embase,Web of Science数据库进行鉴定。

Two independent reviewers performed twostage screening and data extraction. A favorable result was defined as a final House-Brackmann grade I-III and is presented as ratio of all patients in percentage. Pooled proportions were calculated using random-effects models.Results: From 4,932 screened records, 54 studies with 1358 patients were included.A favorable result was achieved after DFS in 42.67% of the patients (CI: 26.05% to 61.12%), after FIGS in 66.43% (CI: 55.99% to 75.47%), after HFS in 63.89% (95% CI: 54.83% to 72.05%), after MFS in 63.11% (CI: 38.53% to 82.37%), and after CFS in 46.67% (CI: 24.09% to 70.70%).

两名独立审稿人进行了两阶段筛选和数据提取。有利的结果被定义为最终的House-Brackmann I-III级,并以所有患者的百分比表示。使用随机效应模型计算合并比例。结果:从4932份筛查记录中,纳入了54项研究,其中1358名患者。DFS后42.67%(CI:26.05%〜61.12%),无花果后66.43%(CI:55.99%〜75.47%),HFS后63.89%(95%CI:54.83%〜72.05%),MFS后63.11%(CI:38.53%〜82.37%),CFS后46.67%(CI:24.09%〜70.70%)。

There was no statistically significant difference between the techniques (Q = 6.56, degrees of freedom = 4, p = 0.1611).The established facial nerve reconstruction techniques including the single nerve cross transfer techniques produce satisfactory results in most of the patients with permanent flaccid facial paralysis.

。包括单神经交叉移植技术在内的已建立的面神经重建技术在大多数永久性弛缓性面瘫患者中产生了令人满意的结果。

An international consensus on a standardized outcome measures would improve the comparability of facial reanimation techniques..

关于标准化结果测量的国际共识将提高面部复苏技术的可比性。。