SOMERSET, N.J.--(BUSINESS WIRE)--Bonerge Lifesience is excited to announce the launch of its new branded ingredient, GlucoVest, designed to support blood sugar and lipid metabolism as well as weight management. As Berberine and its so-called 'natural Ozempic' gain viral popularity on TikTok, many supplement brands incorporate Berberine into their products.

新泽西州萨默塞特（商业新闻短讯）--Bonerge Lifescience很高兴宣布推出其新品牌成分GlucoVest，旨在支持血糖和脂质代谢以及体重管理。随着小檗碱及其所谓的“天然臭氧”在TikTok上获得了病毒般的流行，许多补充剂品牌将小檗碱纳入其产品中。

To meet the increasing demand for higher quality products, Bonerge introduces GlucoVest, a superior Dihydroberberine ingredient, offering a new option for supplement brands..

为了满足对更高质量产品日益增长的需求，Bonerge推出了GlucoVest，一种优质的二氢小檗碱成分，为补充剂品牌提供了新的选择。。

Dihydroberberine, GlucoVest’s active component, is a Berberine derivative with similar benefits. Importantly, Dihydroberberine has better bioavailability than Berberine. Unlike Berberine, which has been reported to cause side effects such as vomiting, Dihydroberberine has no report of adverse effects in published toxicology studies..

GlucoVest的活性成分二氢小檗碱是一种具有类似益处的小檗碱衍生物。重要的是，二氢小檗碱比小檗碱具有更好的生物利用度。与据报道会引起呕吐等副作用的小檗碱不同，二氢小檗碱在已发表的毒理学研究中没有不良反应的报道。。

Berberine's surge in popularity is due to its weight loss mechanism similar to Semaglutide's. As both of them can boost the secretion of GLP-1.1 GLP-1 increases satiety, reduces food intake, enhances energy expenditure, and delays gastric emptying time.2 Besides its weight loss effects, research indicates that Berberine can improve insulin sensitivity3, reduce blood sugar levels4, and enhance lipid metabolism by promoting the conversion of white fat to brown fat and lowering plasma LDL cholesterol, free fatty acids, and total cholesterol levels.

小檗碱的受欢迎程度激增是由于其减肥机制与Semaglutide相似。由于两者都可以促进GLP-1的分泌，GLP-1可以增加饱腹感，减少食物摄入，增加能量消耗，延缓胃排空时间。2除了减肥作用外，研究表明小檗碱还可以通过促进白色脂肪向棕色脂肪的转化，降低血浆LDL胆固醇，游离脂肪酸和总胆固醇水平，提高胰岛素敏感性3，降低血糖水平4，增强脂质代谢。

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Through extensive research and development, GlucoVest is produced with a unique manufacturing procedure that yields high-quality crystalline Dihydroberberine. Even the granulated specifications, can maintain a high assay level compared to other Dihydroberberine on the market while maintaining the flowability of powder.

通过广泛的研究和开发，GlucoVest采用独特的制造工艺生产，可生产出高质量的结晶二氢小檗碱。即使是颗粒状规格，与市场上的其他二氢小檗碱相比，也可以保持较高的测定水平，同时保持粉末的流动性。

This allows for maximizing the efficacy of Dihydroberberine and providing brands with more versatile product applications..

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To further explore the potential and possible applications of GlucoVest, Bonerge plans to conduct self-GRAS certification, efficacy studies, and human trials. For more information, please contact Bonerge.

为了进一步探索GlucoVest的潜力和可能的应用，Bonerge计划进行自我GRAS认证，功效研究和人体试验。有关更多信息，请联系Bonerge。

Reference

参考

Araj-Khodaei, Mostafa et al. “Berberine-induced glucagon-like peptide-1 and its mechanism for controlling type 2 diabetes mellitus: a comprehensive pathway review.”

小檗碱诱导的胰高血糖素样肽-1及其控制2型糖尿病的机制：综合途径综述

Baggio, Laurie L, and Daniel J Drucker. “Biology of incretins: GLP-1 and GIP.”

巴乔、劳里·L和丹尼尔·J·德鲁克。“肠促胰岛素的生物学：GLP-1和GIP。”

Kong, Wei-Jia et al. “Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.”

Mi, Jia et al. “Effect of berberine on the HPA-axis pathway and skeletal muscle GLUT4 in type 2 diabetes mellitus rats.”

Hu, Xiaofei et al. “Berberine is a potential therapeutic agent for metabolic syndrome via brown adipose tissue activation and metabolism regulation.”

小檗碱是一种通过棕色脂肪组织激活和代谢调节来治疗代谢综合征的潜在药物