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The Babinski sign is depicted in numerous historical artworks, with its earliest representation present 400 years before the formal description by Joseph Babinski [1,2,3]. This response is characterized by dorsiflexion of the hallux due to recruiting the extensor hallucis longus muscle, elicited by firmly stroking the foot from heel to toe with a blunt instrument.

巴宾斯基符号在许多历史艺术品中都有描绘，其最早的表现形式比约瑟夫·巴宾斯基（JosephBabinski）的正式描述早400年。。

As a clinical diagnostic tool, the Babinski sign indicates injury to the pyramidal tracts, the primary motor pathway connecting cortical upper motor neurons (UMNs) with spinal cord motor neurons [also known as lower motor neurons (LMNs)]. This sign is present normally in infants, less than 24 months of age (due to incomplete myelination of the pyramidal tracts), and pathologically present in individuals who have sustained prolonged pyramidal tract dysfunction (e.g., stroke, spinal cord injury (SCI), multiple sclerosis and others) [4,5,6].

作为一种临床诊断工具，巴宾斯基征表明锥体束受损，锥体束是连接皮质上运动神经元（UMN）和脊髓运动神经元[也称为下运动神经元（LMN）]的主要运动通路。这种征象通常存在于24个月以下的婴儿（由于锥体束髓鞘不完全），并且在病理上存在于持续锥体束功能障碍（例如中风，脊髓损伤（SCI），多发性硬化症等）的个体中[4,5,6]。

In elderly, gradually compressing the spinal cord and developing myelopathy from chronic spinal stenosis can produce the Babinski sign [7]. The Babinski sign was depicted in several medieval Madonna and Child paintings (e.g., Madonna and Child with Angels by Sandro Botticelli in 1468) [1]. All portray distinct hallux dorsiflexion expected in infants, demonstrating attempts of anatomical precision during this time.After spinal cord injury, a specific pattern of reflex recovery occurs and can be classified into four distinct phases [4].

在老年人中，逐渐压迫脊髓并从慢性椎管狭窄发展为脊髓病可产生巴宾斯基征（7）。巴宾斯基标志在几幅中世纪的圣母与儿童绘画中被描绘出来（例如，桑德罗·波提切利（SandroBotticelli）于1468年创作的《圣母与天使的孩子》（Madonna and Child with Angels）〔1〕。所有这些都描绘了婴儿预期的明显的拇趾背屈，证明了在此期间解剖精度的尝试。脊髓损伤后，发生特定的反射恢复模式，可分为四个不同的阶段（4）。

Immediately upon SCI, in phase 1 of spinal shock all reflexes are initially absent. A few hours after injury, pathological deep tendon reflexes may appear transiently. The Babinski sign can return as early as 1–3 days post-injury, during phase 2, if subjects are elderly [6]. Usually, the sign appears 4–30 days post-injury in phase 3, closely fol.

脊髓损伤后，在脊髓休克的第一阶段，所有反射最初都不存在。受伤后数小时，可能会短暂出现病理性深部肌腱反射。如果受试者是老年人，巴宾斯基征最早可以在受伤后1-3天恢复，在第2阶段。。

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Fig. 1: Depiction of the Babinski sign in Perseus with the Head of Medusa (c. 1545–1554) by Benvenuto Cellini, Piazza della Signoria, Florence.

图1：佛罗伦萨Signoria广场Benvenuto Cellini绘制的珀尔修斯（Perseus）上带有美杜莎（Medusa）头像的巴宾斯基标志（约1545-1554年）。

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Download referencesAcknowledgementsIn memoriam of Dr. John Francis Ditunno Jr (1932–2024), we would like to express our deepest appreciation for his imperative contributions to rehabilitation medicine and spinal cord injury research. His research on spinal shock were crucial to this manuscript.

下载参考文献致谢在纪念John Francis Ditunno Jr博士（1932-2024）时，我们要对他对康复医学和脊髓损伤研究的重要贡献表示最深切的感谢。他对脊柱休克的研究对这份手稿至关重要。

He was an excellent physician, professor, and a great friend. He combined his two passions, medicine, and stone sculpting to create numerous wheelchair carvings inspired by individuals with SCI. Dr. Krassioukov’s laboratory is supported by funds from the Canadian Institutes of Health Research, Heart and Stroke Foundation, Canadian Foundation for Innovation, BC Knowledge Development Fund, US Dept.

他是一位优秀的医生、教授和好朋友。他将医学和石雕这两种激情结合起来，创作了许多轮椅雕刻，灵感来自SCI患者。Krassioukov博士的实验室得到了加拿大卫生研究院、心脏与中风基金会、加拿大创新基金会、不列颠哥伦比亚省知识发展基金会、美国部门的资助。

of Defense, and the Craig H. Neilsen Foundation, International Spinal Research Trust, Wings for Life Spinal Cord Research Foundation. Dr. Sachdeva is supported by the Wings for Life Spinal Cord Research Foundation and US Dept. of Defense. L. Rietchel would like to acknowledge the Doctor of Medicine Undergraduate Program and the Flexible Enhanced Learning (FLEX) Program at the University of British Columbia.

国防部和克雷格·尼尔森基金会，国际脊柱研究信托基金会，生命之翼脊髓研究基金会。Sachdeva博士得到了生命之翼脊髓研究基金会和美国国防部的支持。五十、 Rietchel想感谢不列颠哥伦比亚大学的医学博士本科课程和灵活增强学习（FLEX）课程。

Megan Lee is supported by UBC work learn program.Author informationAuthors and AffiliationsInternational Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, CanadaRahul Sachdeva, Lauren Rietchel, Megan Lee & Andrei V. KrassioukovDepartment of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, Vancouver, BC, CanadaRahul Sachdeva & Andrei V.

梅根·李（Megan Lee）得到了UBC工作学习计划的支持。作者信息作者和附属机构不列颠哥伦比亚大学修复发现国际合作组织（ICORD），不列颠哥伦比亚大学，温哥华，加那拉胡尔·萨赫德瓦，劳伦·里切尔，梅根·李和安德烈·V·克拉西乌科夫不列颠哥伦比亚大学物理医学与康复系，不列颠哥伦比亚大学，温哥华，加那拉胡尔·萨赫德瓦和安德烈·V。

KrassioukovSection of Sports & Exercise Medicine, Department of Family & Community Medicine, University of Toronto, Toronto, ON, CanadaDmitri Krassioukov-EnnsJefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USAJohn DitunnoGF Stro.

加拿大安大略省多伦多市多伦多大学家庭与社区医学系运动与运动医学系Krassioukov EnnsJefferson医学院，美国宾夕法尼亚州费城托马斯杰斐逊大学John DitunnoGF Stro。

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PubMed Google ScholarContributionsRS, AVK, and JD conceptualized the manuscript; RS and LR wrote the first draft; RS, LR, ML, DKE, JD and AVK edited and approved the final version.Corresponding authorsCorrespondence to

PubMed谷歌学术贡献SRS，AVK和JD将手稿概念化；RS和LR撰写了初稿；RS、LR、ML、DKE、JD和AVK编辑并批准了最终版本。通讯作者通讯

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Additional informationPublisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Rights and permissionsSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.Reprints and permissionsAbout this articleCite this articleSachdeva, R., Rietchel, L., Lee, M.

Additional informationPublisher的注释Springer Nature在已发布的地图和机构隶属关系中的管辖权主张方面保持中立。权利和许可Pringer Nature或其许可人（例如协会或其他合作伙伴）根据与作者或其他权利持有人的出版协议对本文拥有专有权；本文接受稿件版本的作者自行存档仅受此类出版协议和适用法律的条款管辖。转载和许可本文引用本文Sachdeva，R.，Rietchel，L.，Lee，M。

et al. The Babinski Sign in ‘Perseus with the head of Medusa’: revisiting art through a neurological lens..

巴宾斯基（Babinski）在《珀尔修斯与美杜莎之首》（Perseus with The head of Medusa）中的签名：通过神经镜头重访艺术。。

Spinal Cord Ser Cases 10, 45 (2024). https://doi.org/10.1038/s41394-024-00661-2Download citationReceived: 21 December 2023Revised: 24 June 2024Accepted: 05 July 2024Published: 11 July 2024DOI: https://doi.org/10.1038/s41394-024-00661-2Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

脊髓Ser病例10,45（2024）。https://doi.org/10.1038/s41394-024-00661-2Download引文收到日期：2023年12月21日修订日期：2024年6月24日接受日期：2024年7月5日发布日期：2024年7月11日OI：https://doi.org/10.1038/s41394-024-00661-2Share本文与您共享以下链接的任何人都可以阅读此内容：获取可共享链接对不起，本文目前没有可共享的链接。。

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