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西方饮食与慢性病

Western diets and chronic diseases

Nature 等信源发布 2024-07-31 18:04

可切换为仅中文


Abstract‘Westernization’, which incorporates industrial, cultural and dietary trends, has paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style diet emerges as a key stimulus for gut microbial vulnerability, chronic inflammation and chronic diseases, affecting mainly the cardiovascular system, systemic metabolism and the gut.

摘要“西方化”结合了工业,文化和饮食趋势,与全球非传染性疾病的兴起并行。今天,西式饮食成为肠道微生物脆弱性,慢性炎症和慢性疾病的关键刺激因素,主要影响心血管系统,全身代谢和肠道。

Here we review the diet of modern times and evaluate the threat it poses for human health by summarizing recent epidemiological, translational and clinical studies. We discuss the links between diet and disease in the context of obesity and type 2 diabetes, cardiovascular diseases, gut and liver diseases and solid malignancies.

在这里,我们回顾了现代饮食,并通过总结最近的流行病学,转化和临床研究来评估它对人类健康的威胁。。

We collectively interpret the evidence and its limitations and discuss future challenges and strategies to overcome these. We argue that healthcare professionals and societies must react today to the detrimental effects of the Western diet to bring about sustainable change and improved outcomes in the future..

我们共同解释证据及其局限性,并讨论未来的挑战和克服这些挑战的策略。我们认为,医疗保健专业人员和社会必须在今天对西方饮食的有害影响作出反应,以便在未来带来可持续的变化和改善的结果。。

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Fig. 1: Western diets as a source of chronic diseases.Fig. 2: Westernization of diet and microbial rarefaction as a fuel for chronic inflammation and noncommunicable diseases.Fig. 3: The concept of precision nutrition.

。图2:饮食西方化和微生物稀疏作为慢性炎症和非传染性疾病的燃料。图3:精确营养的概念。

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U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans www.dietaryguidelines.gov/resources/2020-2025-dietary-guidelines-online-materials (2020).Download referencesAcknowledgementsT.E.A. received funding from the European Research Council under the European Union’s Horizon 2020 Research and Innovation Programme (101039320) and the Austrian Science Fund (P33070 and FG15).Author informationAuthors and AffiliationsDepartment of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology and Metabolism, Medical University of Innsbruck, Innsbruck, AustriaTimon E.

U、 美国农业部和美国卫生与公众服务部。美国人饮食指南www.dietaryguidelines.gov/resources/2020-2025-Dietary-Guidelines-online-materials(2020)。下载referencesAcknowledgementsT。E、 A.获得了欧盟地平线2020研究与创新计划(101039320)和奥地利科学基金(P33070和FG15)下欧洲研究理事会的资助。作者信息作者和附属机构澳大利亚因斯布鲁克医科大学内科I,胃肠学,肝病学,内分泌与代谢系。

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PubMed Google ScholarContributionsT.E.A. and H.T. wrote the manuscript and created the figures.Corresponding authorsCorrespondence to

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Nature Medicine thanks the anonymous reviewers for their contribution to the peer review of this work. Primary Handling Editor: Karen O’Leary, in collaboration with the Nature Medicine team.

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Western diets and chronic diseases..

西方饮食与慢性病。。

Nat Med (2024). https://doi.org/10.1038/s41591-024-03165-6Download citationReceived: 01 March 2024Accepted: 28 June 2024Published: 31 July 2024DOI: https://doi.org/10.1038/s41591-024-03165-6Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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