NEW YORK--(BUSINESS WIRE)--Bonerge is excited to announce the initiation of clinical trials for its high-quality brand ingredients, including GlucoSober and BeFisetin. These trials aim to substantiate the efficacy and safety of the products, providing more reliable options for the market.

纽约--（商业新闻短讯）--博能公司很兴奋地宣布其高质量品牌成分的临床试验开始，其中包括GlucoSober和Befisettin。这些试验旨在证实产品的有效性和安全性，为市场提供更可靠的选择。

In an era where health consciousness is on the rise, consumers are increasingly seeking high-quality dietary supplements. Bonerge is embarking on several clinical trials to make evidence-based ingredients that meet the needs of consumers.

在健康意识日益增强的时代，消费者越来越寻求高质量的膳食补充剂。Bonerge正在进行几项临床试验，以生产满足消费者需求的循证成分。

Key Products Undergoing Clinical Trials

正在进行临床试验的关键产品

BeFisetin®: This high-quality Fisetin with total flavonoids greater than 99%, Fisetin content greater than 98% and impurity smaller than 1%. Previous preclinical studies have shown that fisetin can effectively clear senescent cells, targeting one of the hallmarks of aging. [1,2] The upcoming clinical trials will further investigate BeFisetin's potential benefits to support the market..

Befisettin®：这种高质量的非瑟酮，总黄酮大于99%，非瑟酮含量大于98%，杂质小于1%。先前的临床前研究表明，非瑟酮可以有效清除衰老细胞，靶向衰老的标志之一。即将进行的临床试验将进一步研究贝非司汀支持市场的潜在益处。。

GlucoSober®: An ultra-pure Dihydroberberine with stable quality, GlucoSober is a derivative of the popular weight-loss supplement Berberine. While Berberine has a bioavailability of less than 1%, Dihydroberberine has shown more effective. [3] As an ultrapure product, higher purity means more active ingredients that are packed.

GlucoSober®：一种质量稳定的超纯二氢小檗碱，GlucoSober是流行的减肥补充剂小檗碱的衍生物。。[3] 作为超纯产品，纯度越高意味着包装的活性成分越多。

GlucoSober is set to be the product to undergo human clinical trials to validate the benefits of Dihydroberberine..

GlucoSober将成为进行人体临床试验的产品，以验证二氢小檗碱的益处。。

Additionally, Bonerge will conduct clinical research on product formulations to investigate the synergistic effects of ingredients to meet personalized demand. Further details will be announced.

此外，Bonerge将对产品配方进行临床研究，以研究成分的协同作用，以满足个性化需求。更多细节将公布。

The Initiates of Choosing Clinical Trials

选择临床试验的倡导者

Exploring the functions and applications of ingredients requires collaboration among scientists, manufacturers, and brands. As the mainstream Dihydroberberine supplier, Bonerge continues to explore scientifically proven health longevity and metabolic health ingredients. Bonerge partners with leading brands to ensure consumers have access to high-quality products that help them to maintain a balanced blood glucose level..

。作为二氢小檗碱的主流供应商，Bonerge继续探索科学证明的健康长寿和代谢健康成分。Bonerge与领先品牌合作，确保消费者能够获得高质量的产品，帮助他们维持平衡的血糖水平。。

About Bonerge

关于Bonerge

Bonerge is one innovative team and lab specialized in longevity and metabolic health ingredients. Bonerge closely follow up on the latest anti-aging science, develop novel longevity ingredients. Bonerge is guided by 12 hallmarks of aging. Live longer and healthier.

Bonerge是一个创新团队和实验室，专门研究长寿和代谢健康成分。Bonerge密切关注最新的抗衰老科学，开发新型长寿成分。Bonerge以衰老的12个标志为指导。活得更长更健康。

References

参考文献

1. Yousefzadeh, Matthew J et al. “Fisetin is a senotherapeutic that extends health and lifespan.” EBioMedicine vol. 36 (2018): 18-28. doi:10.1016/j.ebiom.2018.09.015

1.Yousefzadeh，Matthew J等人。“非瑟汀是一种延长健康和寿命的治疗药物。”EBioMedicine vol.36（2018）：18-28。

2. López-Otín, Carlos et al. “Hallmarks of aging: An expanding universe.” Cell vol. 186,2 (2023): 243-278. doi:10.1016/j.cell.2022.11.001

2.López-Otín，Carlos等人，《衰老的标志：膨胀的宇宙》，《细胞》第186,2卷（2023年）：243-278。doi:10.1016/j.cell.2022.11.001

3. Xu, Hong-Yu et al. “Nanoemulsion improves hypoglycemic efficacy of berberine by overcoming its gastrointestinal challenge.” Colloids and surfaces. B, Biointerfaces vol. 181 (2019): 927-934. doi:10.1016/j.colsurfb.2019.06.006

3.Xu，Hong Yu等人，“纳米乳剂通过克服其胃肠道挑战来改善小檗碱的降血糖功效。”胶体和表面。B、 生物界面第181卷（2019）：927-934。doi:10.1016/j.colsurfb.2019.06.006