AbstractIt has not yet been proven whether sepsis affects the tissue around the anal canal. To address this issue, we established three-dimensional models for various types of anorectal abscesses and utilize 3D reconstruction of Magnetic Resonance Imaging scans to assess the extent of muscle damage caused by anorectal abscesses.

摘要脓毒症是否影响肛管周围组织尚未得到证实。为了解决这个问题，我们为各种类型的肛门直肠脓肿建立了三维模型，并利用磁共振成像扫描的3D重建来评估肛门直肠脓肿引起的肌肉损伤程度。

Patients diagnosed with anorectal abscess, selected from January 2019 to January 2022 underwent pre- and post-operative scanning of pelvic floor and perianal tissues. The aforementioned structures were segmented for the reconstruction of a three-dimensional visual model and measurement of volumes for the abscess as well as the internal and external sphincters and levator ani muscle.

2019年1月至2022年1月选择的被诊断为肛门直肠脓肿的患者接受了盆底和肛周组织的术前和术后扫描。对上述结构进行分割，以重建三维视觉模型并测量脓肿以及内外括约肌和肛提肌的体积。

The study included a total of 42 patients. Three-dimensional visualization models were created for different types of anorectal abscesses, including perianal, intersphincteric, ischiorectal, and supralevator abscesses. No statistically significant differences were observed in the volume of the internal sphincter, external sphincter, and levator ani muscle between pre- and post-operative patients.

该研究共包括42名患者。为不同类型的肛门直肠脓肿创建了三维可视化模型，包括肛周，括约肌间，坐骨直肠和提上肌脓肿。术前和术后患者的内括约肌，外括约肌和肛提肌的体积无统计学差异。

The 3D model of anorectal abscess, reconstructed from MRI data, offers a precise and direct visualization of the anatomical structures associated with various types of anorectal abscesses. The infection did not result in any damage to the internal and external anal sphincter and levator ani muscle..

根据MRI数据重建的肛门直肠脓肿的3D模型提供了与各种类型的肛门直肠脓肿相关的解剖结构的精确和直接的可视化。感染没有导致肛门内外括约肌和肛提肌的任何损伤。。

IntroductionThe anorectal abscess is a purulent condition that occurs in the soft tissue surrounding the rectum, and it manifests as a common acute infectious disease in humans. Around 90% of idiopathic perianal abscesses are caused by infection of the cryptoglandular glands1. The infection can rupture through the external sphincter, extending beyond the puborectalis or levators and spreading laterally on both sides, resulting in various types of anorectal abscesses such as perianal abscess, intersphincteric abscess, ischiorectal abscess, supralevator abscess, and even horseshoe-shaped ones1,2.Typically, abscesses are categorized as either superficial or deep in relation to the anal sphincter.

引言肛门直肠脓肿是一种化脓性疾病，发生在直肠周围的软组织中，是人类常见的急性传染病。大约90%的特发性肛周脓肿是由隐腺感染引起的1。感染可以通过外括约肌破裂，延伸到耻骨直肠肌或提肌之外，并在两侧横向扩散，导致各种类型的肛门直肠脓肿，如肛周脓肿，括约肌间脓肿，坐骨直肠脓肿，提上肌脓肿，甚至马蹄形脓肿1,2。通常，脓肿被归类为与肛门括约肌相关的浅表或深部脓肿。

In case of deep abscess, imaging may be necessary for definitive diagnosis confirmation. Magnetic resonance imaging (MRI) is increasingly employed for assessing deep anorectal abscesses due to its advantages of providing a clear visualization of the abscess, high resolution of soft tissues, and absence of ionizing radiation3.

如果是深部脓肿，可能需要影像学检查才能确诊。磁共振成像（MRI）越来越多地用于评估深部肛门直肠脓肿，因为它具有提供脓肿清晰可视化，软组织高分辨率和无电离辐射的优点3。

Consequently, MRI has emerged as a crucial method for accurately determining the location of abscesses in relation to structures such as internal and external anal sphincter and levator ani muscle.The abscesses exhibit high-intensity signal shadows in both proton density-weighted images (PDWI) and T2-weighted images (T2WI), with clear contrast between the high-signal pus of the abscess and the low-signal fibrous tissues in T2WI, enabling differentiation from normal tissues4.

因此，MRI已成为准确确定脓肿与肛门内外括约肌和肛提肌等结构相关位置的关键方法。脓肿在质子密度加权像（PDWI）和T2加权像（T2WI）中均显示高强度信号阴影，脓肿的高信号脓液与T2WI中的低信号纤维组织之间形成明显对比，从而能够与正常组织区分4。

Recent studies have confirmed the utility of 3D models derived from MRI-based reconstruction in comprehending the intricate anatomical relationship between fistula tracks and normal tissues in complex anal fistulas Crohn’s fistulas5,6,7. However, it has not yet been proven whether sepsis .

最近的研究证实了基于MRI重建的3D模型在理解复杂肛瘘克罗恩瘘中瘘管轨迹与正常组织之间复杂的解剖关系方面的实用性5,6,7。然而，尚未证实脓毒症是否存在。

Data availability

数据可用性

All data generated and analyzed during this study are available from the corresponding author.

本研究期间生成和分析的所有数据均可从通讯作者处获得。

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Download referencesAcknowledgementsC.W. is supported by National Administration of Traditional Chinese Medicine (2023 Anorectal Disease ZYYZDXK-2023064), Shanghai Top Priority clinical research Center (2023ZZ02003), and Shanghai Hospital Development Center (SHDC22024306).Author informationAuthors and AffiliationsProctology Department, Longhua Hospital Shanghai University of Traditional Chinese Medicine, No.725 South Wanping Road, Shanghai, 200032, ChinaXutao Ma, Yikun Li, Siming Xu & Chen WangShanghai Shumiao Health Cloud Co.

下载referencesAcknowledgementsC。W、 由国家中医药管理局（2023年肛门直肠疾病ZYZDXK-2023064），上海市最高优先临床研究中心（2023ZZ02003）和上海市医院发展中心（SHDC22024306）支持。作者信息作者和附属机构上海中医药大学龙华医院医学科，上海市万平南路725号，200032，中国马旭涛，李一坤，徐思明和陈旺上海舒苗健康云有限公司。

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PubMed Google ScholarContributionsX.M. conducted 3D reconstruction and drafted the manuscript, while Y.L. and S.X. performed data collection. B.W. performed statistical analysis. C.W. was responsible for study design and clinical treatment. All authors made significant contributions to revising the manuscript for important intellectual content.

PubMed谷歌学术贡献x。M、 进行了3D重建并起草了手稿，而Y.L.和S.X.进行了数据收集。B、 W.进行统计分析。C、 W.负责研究设计和临床治疗。所有作者都为修改手稿的重要知识内容做出了重大贡献。

The final draft was reviewed and approved by all authors.Corresponding authorCorrespondence to.

所有作者都审查并批准了最终草案。对应作者对应。

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Reprints and permissionsAbout this articleCite this articleMa, X., Li, Y., Xu, S. et al. The analysis of different types of anorectal abscesses was conducted using the MRI 3D reconstruction technique.

转载和许可本文引用本文Ma，X.，Li，Y.，Xu，S。等人。使用MRI 3D重建技术对不同类型的肛门直肠脓肿进行了分析。

Sci Rep 14, 18473 (2024). https://doi.org/10.1038/s41598-024-66892-3Download citationReceived: 09 December 2023Accepted: 05 July 2024Published: 09 August 2024DOI: https://doi.org/10.1038/s41598-024-66892-3Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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KeywordsMagnetic resonance imagingAnorectal abscessThree-dimensional reconstructionSphincter impairment

关键词磁共振成像直肠脓肿三维重建括约肌损伤

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