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Experts at Cleveland Clinic are hoping to rework the scoring equation that ranks patients awaiting lung transplants and improve overall outcomes.The equation — known as the Composite Allocation Score — ranks transplant candidates based on stability while awaiting the transplant and also chances of survival.
克利夫兰诊所的专家希望重新制定评分方程,对等待肺移植的患者进行评分并改善总体结果。该方程-称为复合分配评分-在等待移植时基于稳定性和存活机会对移植候选者进行排序。
However, the tests used to determine the score are only given to patients twice a year, meaning they go six months without re-evaluation. During that time, their health could change drastically, which prompted Cleveland Clinic experts to seek a solution that evaluates their transplant needs more efficiently. And while the number of patients on the lung transplant waitlist have gone down slightly in recent years, there is still a shortage of available organs in the U.S., according to a Sept.
然而,用于确定分数的测试仅每年两次给予患者,这意味着他们需要六个月而无需重新评估。在此期间,他们的健康状况可能会发生巨大变化,这促使克利夫兰诊所专家寻求更有效地评估其移植需求的解决方案。根据9月的数据,虽然近年来肺移植等候名单上的患者人数略有下降,但美国仍然缺乏可用的器官。
29 Cleveland Clinic news release. Connecting the patients who are most in need of a transplant with a match quickly improves survival outcomes, they said.'The problem with this method is that the scoring equations fail to consider how a patient's health status changes as they spend more time on the list,' Maryam Valapour, MD, a lead author of the study and director of lung transplant outcomes at Cleveland Clinic stated in the news release.
29克利夫兰诊所新闻稿。他们说,将最需要移植的患者与匹配患者联系起来可以快速提高生存率这种方法的问题在于评分方程未能考虑患者的健康状况如何随着他们在名单上花费更多时间而改变,“克利夫兰诊所研究的主要作者兼肺移植结果主任Maryam Valapour博士说在新闻稿中。
'The longer a patient lives with a severe lung disease, the more their risk of developing severe complications increases. This is something clinicians observe every day – that our patients' risk of developing complications changes over time. Therefore, some patients' scores may not reflect how urgently they need a transplant.'For the study — which was published Sept.
“患者患严重肺部疾病的时间越长,患严重并发症的风险就越高。这是临床医生每天观察到的-我们患者发生并发症的风险会随着时间而改变。因此,一些患者的分数可能无法反映他们需要移植的紧急程度这项研究发表于9月。
29 in The American Journal of Respiratory and Critical Care Medicine — researchers evaluated data from 12,000 U.S. adults on the transplant list and found that 11.5 percent of the i.
29在“美国呼吸与重症医学杂志”上,研究人员评估了移植名单上12000名美国成年人的数据,发现11.5%的i。