LINKÖPING, Sweden--(BUSINESS WIRE)--Two analyses have shed light on an important factor when evaluating treatments that significantly reduce bodyweight: their effect on muscle composition. For their multicenter SURPASS-3 MRI study, Eli Lilly and Company selected AMRA® Researcher to measure muscle volume and muscle fat infiltration..

瑞典LINKÖPING-（BUSINESS WIRE）-两项分析揭示了评估显着降低体重的治疗方法时的一个重要因素：它们对肌肉成分的影响。在他们的多中心SUPASS-3 MRI研究中，礼来公司选择了AMRA®研究人员来测量肌肉体积和肌肉脂肪浸润。。

Previous data from the study using AMRA® Researcher, demonstrated that patients treated with tirzepatide showed, in addition to the significant weight reduction, a favorable effect on fat distribution pattern (visceral fat, subcutaneous fat and liver fat). The two analyses presented at the European Association for the Study of Diabetes (EASD) annual meeting this year aim to better understand the effect of tirzepatide on muscle composition..

使用AMRA®研究人员进行的研究的先前数据表明，接受tirzepatide治疗的患者除了显着减轻体重外，还显示出对脂肪分布模式（内脏脂肪，皮下脂肪和肝脏脂肪）的有利影响。今年在欧洲糖尿病研究协会（EASD）年会上提出的两项分析旨在更好地了解替泽帕肽对肌肉成分的影响。。

The first analysis determined the effect of tirzepatide on muscle fat infiltration. It was found that tirzepatide led to a significant reduction in muscle fat infiltration, and this reduction was significantly greater than in patients treated with insulin degludec.

第一项分析确定了替泽帕肽对肌肉脂肪浸润的影响。发现tirzepatide导致肌肉脂肪浸润显着减少，并且这种减少显着大于用胰岛素degludec治疗的患者。

The second analysis examined the effect of tirzepatide on muscle composition (both muscle fat infiltration and muscle volume) using longitudinal data from the UK Biobank imaging study to contextualize the observed changes. Treatment with tirzepatide led to larger reduction than expected in muscle fat infiltration and as-predicted changes in muscle volume..

第二项分析使用来自英国生物库成像研究的纵向数据来研究替泽帕肽对肌肉组成（肌肉脂肪浸润和肌肉体积）的影响，以观察观察到的变化。tirzepatide治疗导致肌肉脂肪浸润和肌肉体积预测变化的减少幅度大于预期。。

Thus far, Eli Lilly and Company's use of AMRA® Researcher in the SURPASS-3 MRI study has shown that tirzepatide not only led to substantial bodyweight reduction, but that it did so with a beneficial effect on fat distribution pattern (visceral fat, subcutaneous fat, and liver fat) and without apparent detrimental changes on muscle composition (muscle volume and muscle fat infiltration)..

到目前为止，Eli Lilly和Company在SUPASS-3 MRI研究中使用AMRA®研究人员表明，tirzepatide不仅可以显着减轻体重，而且可以对脂肪分布模式（内脏脂肪，皮下脂肪）产生有益影响。脂肪和肝脏脂肪），对肌肉成分（肌肉体积和肌肉脂肪浸润）没有明显的有害变化。。

Olof Dahlqvist Leinhard, CEO of AMRA Medical, commented: “As new drugs with meaningful effects on bodyweight are developed, it is important to evaluate their effects beyond just weight change, such as changes in visceral or hepatic fat, muscle fat infiltration and muscle volume”.

AMRA Medical首席执行官Olof Dahlqvist Leinhard评论说：“随着对体重产生有意义影响的新药的开发，评估其影响不仅仅是体重变化，如内脏或肝脏脂肪变化，肌肉脂肪浸润和肌肉体积“。

AMRA® Researcher is a body composition analysis tool, based on a rapid 10-minute MRI scan with the high reproducibility needed for use in multicenter clinical trials. AMRA® Researcher delivers fat distribution and muscle composition measurements with unrivaled accuracy and precision.

AMRA®研究人员是一种身体成分分析工具，基于快速10分钟MRI扫描，具有用于多中心临床试验所需的高重现性。AMRA®研究人员以无与伦比的精确度和精确度提供脂肪分布和肌肉成分测量。

Results of both analyses from SURPASS-3 MRI were presented on October 3rd at the European Association for the Study of Diabetes (EASD) 2023 conference that took place in Hamburg, Germany.

来自SUPASS-3 MRI的两项分析结果于10月3日在德国汉堡举行的欧洲糖尿病研究协会（EASD）2023会议上发表。

If you would like to learn more about the studies presented at EASD, get access to the full abstracts at https://amramedical.com/EASD-2023/

如果您想了解有关EASD上介绍的研究的更多信息，请访问https://amramedical.com/EASD-2023/

About AMRA Medical

关于阿姆拉医疗

AMRA Medical is a health informatics company at the forefront of medical imaging and precision medicine. The company has developed a new global standard in body composition analysis, delivering multiple fat and muscle biomarkers with unrivaled accuracy and precision – all from a rapid whole-body MRI scan..

AMRA Medical是一家位于医学成像和精准医学前沿的健康信息公司。该公司已经开发出一种新的全球身体成分分析标准，通过快速的全身MRI扫描，提供具有无与伦比的准确性和精确度的多种脂肪和肌肉生物标志物。。

Follow AMRA on LinkedIn for the latest updates in body composition and precision medicine.

按照LinkedIn上的AMRA了解身体成分和精准医学的最新更新。