NEW YORK, Oct. 18, 2023 /PRNewswire/ -- Two grants from the National Institute of Allergies and Infectious Diseases (NIAID), a four-year $3.2 million award and a 12-month $550,000 administrative supplement, will support innovative research to advance the understanding of how climate change and extreme weather influence HIV-related health outcomes around the world..

纽约，2023年10月18日/PRNewswire/-国家过敏和传染病研究所（NIAID）的两项拨款，一项为期420万美元的奖项和一项为期12个月的55万美元的行政补充，将支持创新研究促进了解气候变化和极端天气如何影响全世界艾滋病毒相关的健康结果。。

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A multidisciplinary team of researchers from the CUNY Institute for Implementation Science in Population Health (CUNY ISPH) at the CUNY Graduate School of Public Health and Health Policy (CUNY SPH), the University of California, San Francisco (UCSF), the University of California, Santa Barbara (UCSB) and the Icahn School of Medicine at Mount Sinai will examine the effects of extreme weather events, such as heavy rainfall, hurricanes and drought on short and long-term outcomes of more than two million people living with HIV who have enrolled in HIV care at clinics in 44 countries around the world..

加州大学旧金山分校（UCSF），加州大学旧金山分校（UCSF）公共卫生与健康政策研究生院（CUNY SPH）的CUNY人口健康实施科学研究所（CUNY ISPH）的多学科研究小组，加州大学，圣巴巴拉（UCSB）和西奈山伊坎医学院将研究极端天气事件（如暴雨，飓风和干旱）对200多万艾滋病毒感染者的短期和长期结果的影响在世界44个国家的诊所接受艾滋病毒护理。。

'Most of the 37 million people living with HIV are on treatment, which requires continuous access to antiretroviral medications both to ensure a normal life expectancy and prevent onward transmission of the virus,' says CUNY SPH Distinguished Professor of Epidemiology Dr. Denis Nash, executive director of CUNY ISPH and a principal investigator of both studies.

CUNY SPH杰出流行病学教授Denis Nash博士说：“3700万艾滋病毒感染者中的大多数都在接受治疗，这需要持续获得抗逆转录病毒药物，以确保正常的预期寿命并防止病毒的继续传播。”CUNY ISPH执行董事和两项研究的首席研究员。

'We know very little about the ways that extreme weather influences HIV outcomes and, by extension, its past and present influences on the trajectory of the HIV pandemic.'.

“我们对极端天气如何影响艾滋病毒的结果以及它对艾滋病毒大流行轨迹的过去和现在的影响知之甚少。”。

'Drought and extreme rainfall threaten agricultural yields and pastoral conditions, increasing food insecurity, undernutrition, migration and infrastructure erosion,' says co-principal investigator Dr. Sheri D. Weiser, professor of medicine at UCSF and the director of the University of California's Center for Climate, Health and Equity.

UCSF医学教授兼加州大学中心主任Sheri D.Weiser博士说：“干旱和极端降雨威胁着农业产量和牧草条件，增加粮食不安全，营养不良，移民和基础设施侵蚀。气候，健康和公平。

'These climate-related factors likely also increase the risk of poor clinical outcomes among people living with HIV.'Work on the four-year R01 award will combine data sources uniquely suited to characterize the influence of extreme weather on HIV care outcomes. The R01 will center on the global IeDEA cohort collaboration, which includes longitudinal data on more than two million people enrolling in HIV care since 2004 at more than 400 clinics in 44 countries.

“这些与气候有关的因素也可能增加艾滋病毒感染者临床结果不佳的风险。”为期四年的R01奖项的工作将结合独特的数据来源，以描述极端天气对艾滋病毒护理成果的影响。R01将以全球IeDEA队列合作为中心，其中包括自2004年以来在44个国家的400多家诊所登记艾滋病毒护理的200多万人的纵向数据。

IeDEA data includes daily information on clinic visits, antiretroviral medication uptake and HIV-related laboratory tests that can be used to assess several key outcomes, including disruptions in HIV care and treatment, laboratory monitoring, HIV viral suppression and discontinuing care at a clinic.The IeDEA cohort data will be combined with climate-related data sources, including high spatial resolution, daily data on temperature and rainfall data publicly available from UCSB's Climate Hazards InfraRed Precipitation/Temperatures with Station Data (CHIRPS/CHIRTS), which is based on weather-related satellite imagery and weather station data.

IeDEA数据包括关于门诊就诊，抗逆转录病毒药物摄取和HIV相关实验室检测的日常信息，可用于评估几个关键结果，包括HIV护理和治疗中断，实验室监测，HIV病毒抑制和在诊所停止护理。IeDEA队列数据将与气候相关数据源相结合，包括高空间分辨率，UCSB气候危害红外降水/温度与台站数据（啁啾/CHIRTS）公开提供的温度和降雨数据的日常数据，这些数据基于天气相关卫星图像和气象站数据。

With these combined data sources, the team will conduct in-depth analyses to produce some of the first longitudinal studies of the impact of extreme weather on HIV outcomes over time. 'This is an important and novel application of some of UCSB's flagship data resources,' says Dr. Frank Davenport, a co-investigator and associate researcher at UCSB.

有了这些综合数据来源，该团队将进行深入分析，以便对极端天气对艾滋病毒感染结果的影响进行一些首次纵向研究。UCSB联合研究员兼副研究员Frank Davenport博士说：“这是UCSB旗舰数据资源的一个重要而新颖的应用。