Cutting-edge medical technology company launches the first-ever, automated tool for lymph node dissection to support cancer staging for patients with solid tumors

尖端的医疗技术公司推出了首个用于淋巴结清扫的自动化工具，以支持实体瘤患者的癌症分期

ITHACA, N.Y., Nov. 28, 2023 /PRNewswire/ -- Today, FormaPath announced the commercial launch of AdiPress, the first and only automated tool to standardize lymph node dissection. With this innovation, cancer-focused pathology practices can now automate the recovery of lymph nodes within fatty cancer tissue, to ensure more precise staging of cancer patients to guide their follow up therapy intended to prevent cancer recurrence..

ITHACA，N.Y.，2023年11月28日/PRNewswire/-今天，FormaPath宣布AdiPress商业推出，AdiPress是第一个也是唯一一个标准化淋巴结清扫的自动化工具。通过这项创新，以癌症为中心的病理学实践现在可以自动化脂肪癌组织内淋巴结的恢复，以确保癌症患者更精确的分期，以指导他们的后续治疗，旨在预防癌症复发。。

For decades, pathology labs have relied on manual dissection of lymph nodes for cancer staging, using a traditional method that samples a subset of lymph nodes within a tissue specimen using a scalpel, and then relying on this subset to represent all the nodes that were surgically removed. For example, medical society guidelines require a pathologist to check a minimum of 12 nodes to make a staging call for colon cancer.

几十年来，病理学实验室依靠手工解剖淋巴结进行癌症分期，使用传统方法，使用手术刀对组织标本内的淋巴结子集进行采样，然后依靠该子集代表所有手术节点删除。例如，医学会指南要求病理学家检查至少12个节点以进行结肠癌的分期呼叫。

However, most colon cancer tissue specimens have many more than 12 nodes, thus, the sampling approach always carries the risk that positive nodes can be missed, which may result in 'under-staging', in which case the patient may receive too little follow-up, or adjuvant, therapy, reducing their chances for a successful long-term outcome..

然而，大多数结肠癌组织标本有超过12个淋巴结，因此，抽样方法总是存在可能错过阳性淋巴结的风险，这可能导致“分期不足”，在这种情况下，患者可能接受的太少随访或辅助治疗，减少了获得成功的长期结果的机会。。

'The use of an automated method to identify lymph nodes has the potential to impact colorectal cancer staging after surgery.'

“使用自动化方法识别淋巴结有可能影响手术后的结直肠癌分期。”

-     Dr. Michael Dugan, MD, Chief Medical Officer, FormaPath

-博士。Michael Dugan，医学博士，FormaPath首席医疗官

AdiPress reduces this risk by automating the dissection of lymph nodes from fatty cancer tissue. The proprietary Automated Compressive Filtration (ACF) process performed by AdiPress separates all lymph nodes found in pericolic fat, yielding concentrated lymphatic tissue. This tissue is then captured in square wells within specialized tissue containers called LymFilters, ready for standard microscopic analysis.

AdiPress通过自动解剖脂肪癌组织中的淋巴结来降低这种风险。由AdiPress执行的专有自动压缩过滤（ACF）工艺分离周围脂肪中发现的所有淋巴结，产生浓缩的淋巴组织。然后将该组织捕获在称为LymFilters的专门组织容器内的方形孔中，准备用于标准显微镜分析。

With the use of AdiPress, MD pathologists, pathology assistants, medical oncologists, and patients can be more confident in the accuracy of pathology reports, which will determine their treatment options..

通过使用AdiPress，医学博士病理学家，病理助理，医学肿瘤学家和患者可以对病理报告的准确性更有信心，这将决定他们的治疗选择。。

Importantly, another problem faced by many pathology labs today is a shortage of skilled labor. By automating this nodal dissection step, the time required to isolate relevant lymph nodes is reduced to about 2 minutes, as opposed to tedious, manual dissection that can take up to 45 minutes. Standardization of lymph node dissection via the ACF process ensures reproducibility, reducing variation related to manual dissection by different personnel.

重要的是，今天许多病理学实验室面临的另一个问题是缺乏熟练的劳动力。通过使该淋巴结清扫步骤自动化，分离相关淋巴结所需的时间减少至约2分钟，而繁琐的手动清扫可能需要长达45分钟。通过ACF过程进行淋巴结清扫的标准化确保了可重复性，减少了与不同人员手工解剖相关的变化。

The payoff for laboratories can be significant, as skilled labor can be shifted to other work with the time saved. Removing extraneous fat from lymph nodes using ACF also means that pathologists can review microscopic slides more easily..

实验室的收益可能很重要，因为熟练的劳动力可以在节省时间的情况下转移到其他工作中。使用ACF去除淋巴结中的多余脂肪也意味着病理学家可以更容易地检查显微镜载玻片。。

'The launch of AdiPress is a key turning point for the automated lab of the future. AdiPress, which improves workflow and creates process standardization, will be the future backbone of all labs processing cancer specimens. I look forward to working with labs to demonstrate the immediate value that AdiPress can bring to their operations.'.

'AdiPress的推出是未来自动化实验室的关键转折点。AdiPress改进了工作流程并创建了流程标准化，将成为所有实验室处理癌症标本的未来骨干。我期待与实验室合作，展示AdiPress可以为其运营带来的直接价值。

-     Alex Bodell, Chief Technology Officer, FormaPath

-FormaPath首席技术官Alex Bodell

FormaPath is actively marketing AdiPress to labs in the US to start, focusing on those facilities in cancer centers with high case volumes and hospital networks with multiple labs under management. Any interested labs can request a product demonstration via the FormaPath website.

FormaPath正在积极向美国的实验室推广AdiPress，重点关注病例数量高的癌症中心的设施和管理多个实验室的医院网络。任何感兴趣的实验室都可以通过FormaPath网站请求产品演示。

'Once again I am fortunate to help oncology practice improve as another legacy method for diagnostic classification is upgraded with a new standardized system. Having been involved in precision medicine for over 20 years, it is gratifying to bring this major advance into clinical practice. Unlike other disruptive technologies I have launched, AdiPress serves the interests of all relevant stakeholders.

“我再一次幸运地帮助肿瘤学实践得到改进，因为另一种传统的诊断分类方法通过新的标准化系统升级。20多年来一直参与精准医学，将这一重大进展带入临床实践令人欣慰。与我发起的其他颠覆性技术不同，AdiPress符合所有相关利益相关者的利益。

Nobody who currently works with lymph node dissection will miss the passing of the antiquated and labor-intensive procedure for manual dissection. We believe that once the impact of AdiPress is understood in the wider market, the concept of 'Census-level' dissection will become the new standard for tumor staging, and any approach that relies on mere sampling will be left behind as inadequate.

目前从事淋巴结清扫的人都不会错过手工解剖的过时和劳动密集型手术的通过。我们相信，一旦在更广泛的市场中了解AdiPress的影响，“人口普查水平”解剖的概念将成为肿瘤分期的新标准，任何依赖于单纯抽样的方法都将被忽视。

Patients deserve no less.'.

病人应该得到不少的东西。

-     Ted Snelgrove, Chief Executive Officer, FormaPath

-FormaPath首席执行官Ted Snelgrove

About FormaPath:FormaPath is working to revolutionize cancer staging through cutting-edge laboratory automation equipment. We are dedicated to improving patient care by streamlining and automating the diagnostic process. Our equipment minimizes human errors, allowing for rapid and accurate sample processing, reducing turnaround times, and increasing efficiency..

关于FormaPath:FormaPath正在努力通过尖端的实验室自动化设备彻底改变癌症分期。我们致力于通过简化和自动化诊断过程来改善患者护理。我们的设备可最大程度地减少人为错误，从而实现快速准确的样品处理，缩短周转时间并提高效率。。

With a commitment to research and innovation, we continuously develop state-of-the-art solutions, empowering healthcare professionals to make informed decisions and provide each cancer patient with their best chance at a positive outcome.

通过致力于研究和创新，我们不断开发最先进的解决方案，使医疗保健专业人员能够做出明智的决定，并为每位癌症患者提供最佳的机会，取得积极的成果。

To learn more about FormaPath, visit formapath.com.

要了解有关FormaPath的更多信息，请访问FormaPath.com。

Contact:Phil LonsdaleCommercial Strategy, FormaPath[email protected]

联系方式：Phil LonsdaleCommercial Strategy，FormaPath[电子邮件保护]

SOURCE FormaPath

SOURCE FormaPath