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register hereIntroduction: Antisocial Personality Disorder (ASPD) is characterized by a pervasive pattern of disregard for and violation of the rights of others, typically emerging by age 15 years and involving behaviors such as deceitfulness, impulsivity, and aggressiveness. The present study sought to examine the prevalence of the comorbid ASPD in adult people with Alcohol Dependence Syndrome (ADS) and identify clinical characteristics associated with ASPD.A cross-sectional study of 100 consecutive subjects diagnosed with ADS was conducted.

简介：反社会人格障碍（ASPD）的特征是无视和侵犯他人权利的普遍模式，通常在15岁时出现，涉及欺骗，冲动和攻击性等行为。本研究旨在检查成年酒精依赖综合征（ADS）患者合并ASPD的患病率，并确定与ASPD相关的临床特征。对连续100名被诊断患有ADS的受试者进行了横断面研究。

Subjects were examined between August 2023 and September 2023. Various assessments and questionnaires were employed, including the Montreal Cognitive Assessment (MoCA), Alcohol Use Disorders Identification Test (AUDIT), and Structured Clinical Interview for DSM-IV (SCID-II). A computed tomography (CT) scan of the brain was performed on 47.5% participants.Results: Out of the 100 individuals screened for the study, 20 were excluded.

在2023年8月至2023年9月期间对受试者进行了检查。采用了各种评估和问卷，包括蒙特利尔认知评估（MoCA），酒精使用障碍识别测试（AUDIT）和DSM-IV结构化临床访谈（SCID-II）。47.5%的参与者进行了脑部计算机断层扫描（CT）扫描。结果：在筛选的100名研究对象中，有20名被排除在外。

The study found that 35% of the examined study participants had a comorbid ASPD. Individuals with both ADS and ASPD were more likely to be younger, started drinking at an earlier age, had higher hospitalization rates, and scored higher on the AUDIT test (all P < 0.05%). Also, they had lower education levels, higher rates of unemployment, and lower marriage rates (all P < 0.05%).

该研究发现，35%的受试研究参与者患有共病ASPD。同时患有ADS和ASPD的个体更可能年轻，更早开始饮酒，住院率更高，并且在AUDIT测试中得分更高（均P＜0.05%）。此外，他们的教育水平较低，失业率较高，结婚率较低（均P＜0.05%）。

In addition, they reported more family members with ADS, incarceration, or mental illness and a higher frequency of traumatic experiences (all P < 0.05%). Depression, anxiety, stress (all P < 0.05%), and sleep problems (P = 0.058) were correlated with ASPD. Participants with the comorbid ASPD had lower MoCA scores (P = 0.046) and struggled with attention and linguistic subtests compared to subjects with ADS only.The study.

此外，他们报告说，有更多家庭成员患有广告、监禁或精神疾病，创伤经历的频率更高（均P＜0.05%）。抑郁、焦虑、压力（均P＜0.05%）和睡眠问题（P＝0.058）与ASPD相关。。这项研究。