An integrative single-cell analysis of the human colorectum reveals tumor-associated cellular alterations and regulatory pathways. Patient stratification based on cellular composition of the tumor microenvironment suggests distinct immune evasion mechanisms in colorectal cancer.

人类结直肠的综合单细胞分析揭示了肿瘤相关的细胞改变和调节途径。基于肿瘤微环境的细胞组成的患者分层表明结直肠癌中不同的免疫逃避机制。

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Fig. 1: Schematic of dominant immune evasion mechanisms in diverse tumor microenvironments.

图1：不同肿瘤微环境中主要免疫逃避机制的示意图。

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Download referencesAdditional informationPublisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Chu, X. et al. Integrative single-cell analysis of human colorectal cancer reveals patient stratification with distinct immune evasion mechanisms.

下载参考其他信息出版商的注释Springer Nature对于已发布地图和机构隶属关系中的管辖权主张保持中立。这是Chu，X。等人的总结。人类结直肠癌的综合单细胞分析揭示了具有不同免疫逃避机制的患者分层。

Nat. Cancer https://doi.org/10.1038/s43018-024-00807-z (2024).Rights and permissionsReprints and permissionsAbout this articleCite this article Single-cell atlas defines distinct immune escape mechanisms in colorectal cancer..

自然癌症https://doi.org/10.1038/s43018-024-00807-z（2024年）。权利和许可打印和许可本文引用本文单细胞图谱定义了结直肠癌中不同的免疫逃逸机制。。

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