Gene therapy holds tremendous promise for treating a wide range of hereditary and acquired diseases by delivering exogenous therapeutic nucleotide sequences into specific cells or tissues. Recent advances support the notion that gene therapy could offer a long-term cure for diabetes mellitus, something that current conventional pharmacotherapies cannot achieve..

通过将外源性治疗性核苷酸序列递送到特定细胞或组织中，基因疗法对于治疗广泛的遗传性和获得性疾病具有巨大的前景。最近的进展支持这样的观点，即基因治疗可以为糖尿病提供长期治疗，这是目前常规药物治疗无法实现的。。

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Download referencesAcknowledgementsThe authors acknowledge the support of the German Research Foundation (DFG, IRTG3019).Author informationAuthors and AffiliationsDepartment of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, GermanyStefan R.

下载参考文献致谢作者感谢德国研究基金会（DFG，IRTG3019）的支持。作者信息作者和附属机构德国德累斯顿德累斯顿工业大学Carl Gustav Carus大学医院内科III。

Bornstein & Charlotte SteenblockSchool of Cardiovascular and Metabolic Medicine and Sciences, Faculty of Life Sciences & Medicine, King’s College London, London, UKStefan R. BornsteinKriya Therapeutics, Palo Alto, CA, USAJ. Fraser WrightDivision of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USAJ.

Bornstein和Charlotte SteenblockSchool of Cardiovascular and Metabolic Medicine and Sciences，Faculty of Life Sciences&Medicine，King's College London，London，UKStefan R.BornsteinKriya Therapeutics，Palo Alto，CA，USAJ。弗雷泽·赖特美国加利福尼亚州斯坦福市斯坦福大学医学院儿科血液学、肿瘤学、干细胞移植和再生医学系。

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Fraser WrightAuthorStefan R.BornsteinView作者出版物您也可以在中搜索此作者。

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Stefan R. Bornstein.Ethics declarations

斯特凡·博恩斯坦（StefanR.Bornstein）。道德宣言

Competing interests

相互竞争的利益

J.F.W. is scientific co-founder and chief gene therapy officer at Kriya Therapeutics. S.R.B. and C.S. declare no competing interests.

J、 F.W.是Kriya Therapeutics的科学联合创始人兼首席基因治疗官。S、 R.B.和C.S.声明没有利益冲突。

Rights and permissionsReprints and permissionsAbout this articleCite this articleBornstein, S.R., Wright, J.F. & Steenblock, C. The promising potential of gene therapy for diabetes mellitus.

权利和许可本文引用本文Bornstein，S.R.，Wright，J.F。＆Steenblock，C。糖尿病基因治疗的前景。

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