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register hereBackground: Depression is a common mental illness with a high prevalence in overweight or obese individuals. Recent studies suggest that the Metabolic Score for Visceral Fat (METS-VF) is a novel metric for assessing visceral fat levels, potentially linking metabolic disturbances to depression.

背景：抑郁症是一种常见的精神疾病，在超重或肥胖人群中患病率很高。最近的研究表明，内脏脂肪代谢评分（METS-VF）是评估内脏脂肪水平的一种新指标，可能将代谢紊乱与抑郁症联系起来。

This study explores the association between METS-VF and depression severity in overweight or obese U.S. adults.: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007-2018 dataset, including 9,415 overweight or obese participants. Depression severity was measured using the Patient Health Questionnaire-9 (PHQ-9).

这项研究探讨了美国超重或肥胖成年人中METS-VF与抑郁严重程度之间的关系：数据来自2007-2018年国家健康与营养调查（NHANES）数据集，包括9415名超重或肥胖参与者。使用患者健康问卷-9（PHQ-9）测量抑郁严重程度。

To assess the association between METS-VF and depression, the study methodology included multivariate logistic regression, subgroup analyses, generalized additive model (GAM), and smoothed curve fitting. This study also calculated BMI for the Non-Hispanic Asian population from 2011-2018 and incorporated this data as part of a sensitivity analysis.

为了评估METS-VF与抑郁症之间的关联，研究方法包括多变量逻辑回归，亚组分析，广义加性模型（GAM）和平滑曲线拟合。这项研究还计算了2011-2018年非西班牙裔亚洲人群的BMI，并将这些数据作为敏感性分析的一部分。

Results: Elevated levels of METS-VF in overweight or obese participants were significantly associated with increased PHQ-9 scores and an increased likelihood of 2 / 20 depression. Notably, this association remained significant after adjustment for multiple covariates. Smoothed curve-fitting plots showed no nonlinear association between METS-VF and PHQ-9 scores.

结果：超重或肥胖参与者中METS-VF水平升高与PHQ-9评分增加和2/20抑郁可能性增加显着相关。值得注意的是，在调整了多个协变量后，这种关联仍然很重要。平滑曲线拟合图显示METS-VF和PHQ-9评分之间没有非线性关联。

Subgroup analyses confirmed the robustness of these results across populations, particularly among people under the age of fifty. The sensitivity analyses confirmed the robustness of the results in this study. Conclusion: METS-VF levels were positively associated with depression severity and the likelihood of depression in overweight or obese individuals, with the association being particularly pronounced in people .

亚组分析证实了这些结果在人群中的稳健性，特别是在50岁以下的人群中。敏感性分析证实了本研究结果的稳健性。结论：METS-VF水平与超重或肥胖个体的抑郁严重程度和抑郁可能性呈正相关，这种关联在人群中尤为明显。