Seegene Inc., a leading provider of total solution for PCR molecular diagnostics based in South Korea, announced today that it will introduce a new type of research-use-only (RUO) PCR assay to address the spread of the mpox virus variant, Clade Ib, which is currently prevalent in Africa.The newly introduced Novaplex™ MPXV/OPXV plus Assay (RUO) is designed to detect 3 targets causing mpox disease: non-variola Orthopoxvirus (OPXV) and mpox virus (MPVX) with specific confirmation of MPXV Clade I.

位于韩国的PCR分子诊断总体解决方案的领先供应商Seegene Inc.今天宣布，它将推出一种新型的研究用途（RUO）PCR检测方法，以解决目前在非洲流行的mpox病毒变体Clade Ib的传播问题。新推出的Novaplex™MPXV/OPXV plus检测（RUO）旨在检测引起mpox疾病的3个靶标：非天花正痘病毒（OPXV）和mpox病毒（MPVX），并对MPXV进化枝I进行特异性确认。

MPXV Clade I is associated with higher transmission and mortality rates than MPXV Clade II. The assay meets the preferred target product profiles (TPPs) issued by the WHO, which guide manufacturers, suppliers, and researchers developing new assays for detection of viruses causing mpox. Additionally, it aligns with the preferred target analyte criteria for distinguishing between Clade I and II.Seegene has been responding swiftly to the August 2024 global public health emergency (PHEIC) declared by the WHO regarding the mpox outbreak by developing two assays designed to detect mpox virus and announcing plans to supply the products to countries in need.Among these, Novaplex™ MPXV/OPXV Assay (RUO) is designed to detect MPXV Clade I and Clade II as well as OPXV infections, while Novaplex™ HSV-1&2/VZV/MPXV Assay (RUO) is designed to simultaneously detect four viruses including MPXV, herpes simplex virus (HSV) Types 1 and 2, and varicella-zoster virus (VZV).

MPXV进化枝I比MPXV进化枝II具有更高的传播率和死亡率。该检测符合世卫组织发布的首选目标产品概况（TPP），该概况指导制造商，供应商和研究人员开发新的检测mpox病毒的检测方法。此外，它与用于区分进化枝I和II的首选目标分析物标准一致。世卫组织宣布2024年8月全球公共卫生紧急情况（PHEIC）爆发mpox疫情，Seegene开发了两种检测mpox病毒的检测方法，并宣布计划向有需要的国家提供这些产品，从而迅速应对了这一事件。其中，Novaplex™MPXV/OPXV检测（RUO）旨在检测MPXV进化枝I和进化枝II以及OPXV感染，而Novaplex™HSV-1和2/VZV/MPXV检测（RUO）旨在同时检测四种病毒，包括MPXV，单纯疱疹病毒（HSV）1型和2型以及水痘带状疱疹病毒（VZV）。

These products also comply with TPPs issued by the WHO.'As the spread of mpox continues unabated, we have developed new RUO assays for detection of viruses causing the mpox to meet the increasing research demand from affected countries. We are committed to actively supporting global efforts to curb the spread of mpox,' said Daniel Sh.

这些产品也符合世卫组织发布的TPP。”随着mpox的传播继续有增无减，我们开发了新的RUO检测方法，用于检测导致mpox满足受影响国家日益增长的研究需求的病毒。丹尼尔·什说，我们致力于积极支持全球遏制mpox传播的努力。