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了解种子萌发过程中细胞类型的特异性调控

Understanding cell-type-specific regulation during seed germination

Nature 等信源发布 2024-09-10 21:15

可切换为仅中文


A seed reactivates its genome to germinate. By creating a single-cell atlas of germinating embryos, we show that gene expression is highly dynamic and cell specific. Most cells adopt a single, common transcriptional state early in germination, and then transition to distinct gene regulatory programs that drive the functions of individual cell types..

种子重新激活其基因组以发芽。通过创建发芽胚胎的单细胞图谱,我们表明基因表达是高度动态和细胞特异性的。大多数细胞在萌发早期采用单一的共同转录状态,然后过渡到驱动单个细胞类型功能的不同基因调控程序。。

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Fig. 1: Cell cluster distribution in the germinating Arabidopsis embryo.

图1:发芽拟南芥胚胎中的细胞簇分布。

ReferencesBassel, G. W. et al. Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions. Proc. Natl Acad. Sci. USA 108, 9709–9714 (2011). This paper presents a network model of global transcriptional interactions (SeedNet) of dormancy and germination in seeds.Article .

。程序。国家科学院。科学。美国1089709–9714(2011)。本文提出了种子休眠和萌发的全局转录相互作用(SeedNet)的网络模型。文章。

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Topham, A. T. et al. Temperature variability is integrated by a spatially embedded decision-making center to break dormancy in Arabidopsis seeds. Proc. Natl Acad. Sci. USA 114, 6629–6634 (2017). This paper reports the discovery of a decision-making centre within dormant seeds.Article .

Topham,A.T。等人。温度变异性通过空间嵌入的决策中心进行整合,以打破拟南芥种子的休眠。程序。国家科学院。科学。美国1146629–6634(2017)。本文报道了在休眠种子中发现决策中心的情况。文章。

PubMed

PubMed

PubMed Central

公共医学中心

Google Scholar

谷歌学者

Lin, C., Ding, J. & Bar-Joseph, Z. Inferring TF activation order in time series scRNA-seq studies. PLoS Comput. Biol. 16, e1007644 (2022). This paper presents the development of the continuous-state hidden Markov models transcription factor (CSHMM-TF) method and its use in predicting transcription factor activation time in scRNA-seq data.Narsai, R.

Lin,C.,Ding,J。&Bar Joseph,Z。在时间序列scRNA-seq研究中推断TF激活顺序。PLoS计算机。生物学16,e1007644(2022)。本文介绍了连续状态隐马尔可夫模型转录因子(CSHMM-TF)方法的发展及其在预测scRNA-seq数据中转录因子激活时间中的应用。纳尔塞,R。

et al. Extensive transcriptomic and epigenomic remodelling occurs during Arabidopsis thaliana germination. Genome Biol. 18, 1–18 (2017). This paper presents transcriptomic and epigenomic data during A. thaliana germination.Article .

在拟南芥萌发过程中发生了广泛的转录组学和表观基因组重塑。基因组生物学。18,1-18(2017)。本文介绍了拟南芥萌发过程中的转录组学和表观基因组学数据。文章。

Google Scholar

谷歌学者

Liew, L. C. et al. Temporal tissue‐specific regulation of transcriptomes during barley (Hordeum vulgare) seed germination. Plant J. 101, 700–715 (2020). This paper reports tissue-specific transcriptomes during barley seed germination.Article

Liew,L.C.等人。大麦(Hordeum vulgare)种子萌发过程中转录组的时间组织特异性调控。工厂J.101700–715(2020)。本文报道了大麦种子萌发过程中的组织特异性转录组。文章

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PubMed

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Download referencesAdditional informationPublisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.This is a summary of: Liew, L. C. et al. Establishment of single-cell transcriptional states during seed germination.

下载参考其他信息出版商的注释Springer Nature对于已发布地图和机构隶属关系中的管辖权主张保持中立。这是Liew,L.C.等人在种子萌发过程中建立单细胞转录状态的总结。

Nat. Plants https://doi.org/10.1038/s41477-024-01771-3 (2024).Rights and permissionsReprints and permissionsAbout this articleCite this article Understanding cell-type-specific regulation during seed germination..

天然植物https://doi.org/10.1038/s41477-024-01771-3(2024年)。权利和许可打印和许可本文引用本文了解种子萌发过程中细胞类型的特定调控。。

Nat. Plants (2024). https://doi.org/10.1038/s41477-024-01772-2Download citationPublished: 10 September 2024DOI: https://doi.org/10.1038/s41477-024-01772-2Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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