CAMBRIDGE, England--(BUSINESS WIRE)--Cellular Origins, a TTP Company, focused on enabling scalable, cost-effective, and efficient manufacture of cell and gene therapies (CGTs), today announced a collaboration with 3P innovation, a leading engineering company and supplier of automated fill-finish equipment.

英国剑桥--（商业新闻短讯）--Cellular Origins是一家TTP公司，专注于实现细胞和基因疗法（CGT）的可扩展，经济高效和高效制造，今天宣布与领先的工程公司和自动填充精加工设备供应商3P innovation合作。

The partnership will integrate 3P innovation’s cryoFIL™ cryovial filling platform within Cellular Origins’ robotic system, Constellation™, expanding the system’s capabilities by enabling automated filling of cryovials within a closed and sterile environment..

该合作伙伴关系将3P innovation的cryoFIL™冷冻瓶填充平台集成到Cellular Origins的机器人系统Constellation™中，通过在封闭无菌的环境中自动填充冷冻瓶来扩展系统的功能。。

3P innovation’s cryoFIL platform is designed to automate and streamline filling processes in cell and gene therapy workflows, incorporating the Company’s proven technology within a cGMP compliant robotic platform. Designed to provide reliable and repeatable liquid filling, cryoFIL’s automated workflow utilises a closed loop filling and 100% weight verification approach to ensure the maximum yield of manufactured therapies..

3P innovation的cryoFIL平台旨在自动化和简化细胞和基因治疗工作流程中的填充过程，将公司成熟的技术整合到符合cGMP的机器人平台中。cryoFIL的自动化工作流程旨在提供可靠且可重复的液体填充，采用闭环填充和100%重量验证方法，以确保制造疗法的最大产量。。

The collaborative partnership will undertake the physical and digital integration of cryoFIL within Constellation, centring around the development of a system for seamless robotic docking with cryoFIL. The integration will allow manufacturing processes that require interfacing with vials and other open format containers to be fully automated, maximising production efficiencies.

该合作伙伴关系将承担cryoFIL在星座内的物理和数字集成，重点是开发与cryoFIL无缝机器人对接的系统。这种集成将使需要与小瓶和其他开放式容器接口的制造过程实现全自动化，从而最大限度地提高生产效率。

This represents an important milestone in the ongoing development of Constellation as an end-to-end automated solution for cell therapy manufacturing. Further expanding the system’s capabilities, the integration of cryoFIL will enable users to alleviate the requirement for manual and problematic process steps in CGT manufacturing that can require significant time and labour investment..

这是Constellation作为细胞治疗制造的端到端自动化解决方案正在进行的开发中的一个重要里程碑。cryoFIL的集成将进一步扩展系统的功能，使用户可以减轻CGT制造中手动和有问题的工艺步骤的要求，这可能需要大量的时间和人力投资。。

“We are collaborating with the best technologies to solve the most difficult challenges in the field. We are extremely pleased to be working so closely with 3P innovation, harnessing their leading experience and expertise in pharmaceutical manufacturing and aseptic processing.” said Dr Edwin Stone, CEO at Cellular Origins.

Cellular Origins首席执行官埃德温·斯通（Edwin Stone）博士表示：“我们正在与最好的技术合作，以解决该领域最困难的挑战。我们非常高兴能够与3P创新紧密合作，利用他们在制药和无菌加工方面的领先经验和专业知识。”。

He continued: “3P innovation shares our belief that embracing automation is the key to addressing the manufacturing bottleneck and improving accessibility to lifesaving therapies. We are pleased to be collaborating with their team to integrate cryoFIL within Constellation, broadening the system’s capabilities and tackling the complex challenges of fully automating and industrialising CGT manufacturing.”.

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Dr Dave Seaward, Founder, 3P innovation, commented: “Several years ago, we recognised that automation would be a key factor in reducing costs and expanding access to cell and gene therapies. This insight drove us to innovate and transform our large aseptic fill-finish equipment into benchtop formats tailored for this emerging sector.

3P innovation创始人Dave Seaward博士评论道：“几年前，我们认识到自动化将是降低成本和扩大细胞和基因治疗渠道的关键因素。这一见解促使我们创新并将我们的大型无菌填充表面设备转变为专为这一新兴行业量身定制的台式格式。

We are delighted to be working alongside Cellular Origins, combining the benefits of cryoFIL and Constellation to propel our industry forward and revolutionise advanced therapy manufacturing.”.

我们很高兴与Cellular Origins合作，结合cryoFIL和Constellation的优势，推动我们的行业向前发展，彻底改变先进的治疗制造业。”。

Cellular Origins and 3P innovation will be taking part in Phacilitate’s Advanced Therapies Europe from 10-12 September 2024. Visit Booth 44 for more information on the collaboration.

Cellular Origins and 3P innovation将于2024年9月10日至12日参加Phacilitate的欧洲先进疗法。有关合作的更多信息，请访问44号展位。