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register hereBackground: Medical health workers play an essential role in the healthcare system and face unique workplace stressors. However, the impact of psychological stress on their physical health has received less attention compared to the general population.We retrospectively analyzed the Self-rating Depression Scale (SDS) questionnaires and blood testing results from 1963 medical health workers.

注册背景：医疗保健工作者在医疗保健系统中发挥着至关重要的作用，面临着独特的工作压力。然而，与普通人群相比，心理压力对他们身体健康的影响受到的关注较少。我们回顾性分析了1963名医疗保健工作者的抑郁自评量表（SDS）问卷和血液检测结果。

Multivariate linear regression analysis using a backward stepwise selection strategy to identify physical examination indicators that were significantly affected by depression.Results: Depression severity, as measured by SDS index score, was positively correlated with the levels of hemoglobin (coefficient 0.0027, P = 0.0412), platelet count (coefficient 0.0005, P = 0.0198), and uric acid (coefficient 0.0004, P = 0.0492), while negatively correlated with red blood cell count (coefficient -0.0895, P = 0.0406).

使用后向逐步选择策略进行多元线性回归分析，以确定受抑郁症显着影响的体检指标。结果：抑郁严重程度与血红蛋白（系数0.0027，P=0.0412），血小板计数（系数0.0005，P=0.0198）和尿酸（系数0.0004，P=0.0492）呈正相关，而与红细胞计数呈负相关（系数-0.0895，P=0.0406）。

Similar results were observed in the subgroup analysis stratified by age and sex.Our study found a significant association between higher levels of depression and specific physiological indicators in healthcare professionals, including elevated hemoglobin, platelet counts, and uric acid levels, as well as decreased red blood cell counts.

在按年龄和性别分层的亚组分析中观察到类似的结果。。

These changes in blood parameters may reflect underlying physiological stress and inflammation, potentially increasing overall health risks for healthcare workers. Addressing these physiological changes may be crucial for mitigating the health risks associated with depression. To validate our findings and develop targeted interventions, larger multi-center studies are needed to further explore the relationship between depression severity and blood parameters in healthcare professionals..

。解决这些生理变化对于减轻与抑郁症相关的健康风险可能至关重要。为了验证我们的发现并制定有针对性的干预措施，需要进行更大规模的多中心研究，以进一步探索抑郁症严重程度与医疗保健专业人员血液参数之间的关系。。