Vibegron is recommended as an option for treating the symptoms of overactive bladder syndrome in adults

Vibegron被推荐作为治疗成人膀胱过度活动综合征症状的一种选择

It is only recommended if antimuscarinic medicines are not suitable, do not work well enough or have unacceptable side effects. 1.2 If people with the condition and their healthcare professional consider vibegron to be 1 of a range of suitable treatments, after discussing the advantages and disadvantages of all the options, the least expensive should be used.

只有在抗毒蕈碱药物不合适、效果不佳或有不可接受的副作用时才建议使用。1.2如果有这种情况的人和他们的医疗保健专业人员认为vibegron是一系列合适的治疗方法之一，在讨论了所有选择的优缺点之后，应该使用最便宜的方法。

Administration costs, dosages, price per dose and commercial arrangements should all be taken into account..1.3 This recommendation is not intended to affect treatment with vibegron that was started in the NHS before this guidance was published. People having treatment outside this recommendation may continue without change to the funding arrangements in place for them before this guidance was published, until they and their NHS healthcare professional consider it appropriate to stop..

管理成本、剂量、每剂价格和商业安排都应予以考虑。。1.3本建议无意影响在本指南发布之前在NHS开始的vibegron治疗。。。

Why these recommendations were made  Usual treatment for symptoms of overactive bladder syndrome is antimuscarinic medicines. If these are not suitable, do not work well enough or have unacceptable side effects, mirabegron is recommended as a treatment option. Vibegron works in a similar way to mirabegron.

为什么这些建议被用于膀胱过度活动综合征症状的常规治疗是抗毒蕈碱药物。如果这些不合适，效果不佳或有不可接受的副作用，建议将米拉贝隆作为治疗选择。Vibegron的工作方式与mirabegron类似。

This evaluation only looked at vibegron for the same people who would be offered mirabegron. Clinical trial evidence shows that vibegron is more effective than placebo for treating the symptoms of overactive bladder syndrome. The evidence is limited because most people in the trial had not had antimuscarinic medicines.

这项评估只针对将被提供米拉贝格伦的同一个人进行了维贝格伦评估。。证据是有限的，因为试验中的大多数人都没有服用抗毒蕈碱药物。

But the reduction in symptoms was similar for people who had had antimuscarinic medicines and people who had not. The licensed dose of vibegron (75 mg) has not been directly compared in a clinical trial with mirabegron, but an indirect treatment comparison suggests it is likely to work as well.Cost-comparison results suggest vibegron is likely to be cost saving compared with mirabegron.

但服用抗毒蕈碱药物的人和未服用抗毒蕈碱药物的人的症状减轻程度相似。vibegron（75 mg）的许可剂量尚未在临床试验中与mirabegron进行直接比较，但间接治疗比较表明它也可能起作用。成本比较结果表明，与米拉贝隆相比，维贝隆可能节省成本。

So, vibegron is recommended..

因此，建议使用vibegron。。

Condition: Overactive Bladder

病情：膀胱过度活动

Type: drug

类型：药物