CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vizgen, Inc., the life science company dedicated to improving human health through single-cell spatial genomics, proudly announces the first global shipments of the highly anticipated MERSCOPE Ultra™ Platform. This milestone marks a significant step for Vizgen as it begins delivering this next-generation technology to leading research institutions around the world.

马萨诸塞州剑桥市。-（商业新闻短讯）--致力于通过单细胞空间基因组学改善人类健康的生命科学公司Vizgen，Inc.骄傲地宣布，备受期待的MERSCOPE Ultra™平台首次在全球发货。这一里程碑标志着Vizgen迈出了重要的一步，因为它开始向世界各地的领先研究机构提供这种下一代技术。

Among the first to receive the platform are the Institut Pasteur in Paris, France, The Translational Genomics Research Institute (TGen), part of City of Hope in Phoenix, Arizona, and other leading research institutes..

首批获得该平台的有法国巴黎巴斯德研究所、亚利桑那州凤凰城希望之城的转化基因组学研究所（TGen）以及其他领先的研究机构。。

Vizgen initially unveiled the MERSCOPE Ultra Platform at the American Association of Cancer Research (AACR) annual meeting in April 2024, alongside MERFISH 2.0 - an enhanced chemistry that improves RNA anchoring and signal strength, matching MERFISH’s sensitivity and reproducibility even in degraded RNA samples, such as FFPE.

Vizgen最初在2024年4月的美国癌症研究协会（AACR）年会上推出了MERSCOPE Ultra平台，以及MERFISH 2.0，这是一种增强的化学物质，可改善RNA锚定和信号强度，即使在降解的RNA样品（如FFPE）中也能匹配MERFISH的灵敏度和可重复性。

MERFISH 2.0 is set to launch later this year and will be available for both the flagship MERSCOPE® Platform and the MERSCOPE Ultra..

MERFISH 2.0将于今年晚些时候发布，并将用于旗舰MERSCOPE®平台和MERSCOPE Ultra。。

Following the success of the MERSCOPE Platform, the MERSCOPE Ultra represents Vizgen’s next-generation solution, offering high-resolution in situ analysis that maps and quantifies RNA species within tissues. The MERSCOPE Ultra triples the imaging area of its predecessor to 3.0 cm² on a single slide and introduces an interchangeable design with two flow chamber sizes, enabling cost efficiency and flexible experimental set up.

随着MERSCOPE平台的成功，MERSCOPE Ultra代表了Vizgen的下一代解决方案，提供了高分辨率的原位分析，可以绘制和量化组织内的RNA种类。MERSCOPE Ultra在一个载玻片上将其前身的成像面积扩大了三倍，达到3.0 cm²，并引入了具有两种流动室尺寸的可互换设计，从而实现了成本效益和灵活的实验设置。

This flexibility allows researchers to scale up imaging area up to profile larger single samples, or multiple smaller samples in one run and scale down to conserve reagent when running smaller samples. The system also features faster imaging speeds, crucial for handling larger sample areas, and continues to support custom panels of up to 1000 genes, a standard feature since the MERSCOPE’s initial launch..

这种灵活性允许研究人员扩大成像面积，以在一次运行中分析较大的单个样品或多个较小的样品，并在运行较小样品时缩小规模以节省试剂。该系统还具有更快的成像速度，对于处理更大的样本区域至关重要，并继续支持多达1000个基因的定制面板，这是自MERSCOPE首次推出以来的标准功能。。

The Sanderson Center of Optical Experimental at the University of Massachusetts Chan Medical School has been at the forefront of testing Vizgen’s platforms, dating back to 2019 with a MERSCOPE Platform Alpha unit. “We’re thrilled to continue this partnership by being among the first sites in the world to beta test Vizgen's MERSCOPE Ultra Platform.

马萨诸塞大学陈医学院的桑德森光学实验中心一直处于测试Vizgen平台的最前沿，可以追溯到2019年，该中心拥有一个MERSCOPE平台Alpha单元。“作为全球首批测试Vizgen MERSCOPE Ultra平台的网站之一，我们很高兴能够继续保持这种合作关系。

We have been running MERSCOPE Platform projects in our lab for years and are excited about the possibilities that the MERSCOPE Ultra further unlocks. The MERSCOPE Ultra will not only accelerate the research we support by handling bigger and more complex datasets efficiently due to the increased imaging speed but will also enable the application of this technology to new tissues thanks to the greatly enlarged imaging area,” says Christina Baer, PhD, the Director of the SCOPE..

多年来，我们一直在实验室运行MERSCOPE平台项目，对MERSCOPE Ultra进一步解锁的可能性感到兴奋。由于成像速度的提高，MERSCOPE Ultra不仅可以有效地处理更大、更复杂的数据集，从而加速我们支持的研究，而且由于成像面积的大大扩大，这项技术还可以应用于新组织，”SCOPE主任克里斯蒂娜·贝尔博士说。。

Similarly, at the Institut Pasteur, Mélanie Hamon, Head of the Chromatin and Infection Unit, reflects on new possibilities, “The recent installation of the MERSCOPE Ultra at our Center for Technology Resources and Research—funded through the prestigious 'Chaire d’excellence' award from the French Ministry of Research—marks a significant milestone for our 'ChromaBac' project.

同样，在巴斯德研究所，染色质和感染部门负责人梅拉尼·哈蒙（Mélanie Hamon）反思了新的可能性，“最近在我们的技术资源和研究中心安装了MERSCOPE Ultra，这是由法国研究部授予的享有盛誉的“Chaire d'excellence”奖资助的，标志着我们的“ChromaBac”项目的一个重要里程碑。

The MERSCOPE Ultra, with its expanded imaging area and enhanced speed, will be an integral tool in our research, enabling us to delve deeper into the complex interactions between pathogens and host chromatin with unprecedented sensitivity,” says Hamon..

MERSCOPE Ultra具有扩大的成像面积和提高的速度，将成为我们研究中不可或缺的工具，使我们能够以前所未有的灵敏度深入研究病原体与宿主染色质之间的复杂相互作用，”Hamon说。。

“We are thrilled to announce the global launch of the MERSCOPE Ultra Platform, a remarkable achievement for our team. This success showcases our resilience and commitment to advancing spatial genomics,” says Seth Benson, Vizgen CFO. “As we look ahead, the future of Vizgen is brighter than ever, with groundbreaking innovations on the horizon including our MERFISH 2.0 chemistry.

Vizgen首席财务官塞思·本森（SethBenson）表示：“我们很高兴宣布在全球推出MERSCOPE Ultra平台，这对我们的团队来说是一项非凡的成就。这一成功展示了我们对推进空间基因组学的适应能力和承诺。”。“展望未来，Vizgen的未来比以往任何时候都更加光明，包括我们的MERFISH 2.0化学产品在内的开创性创新即将出现。

The MERSCOPE Ultra will enable researchers to make profound discoveries, and we’re excited to continue driving this momentum in the years to come.”.

MERSCOPE Ultra将使研究人员能够做出深刻的发现，我们很高兴在未来几年继续推动这一势头。”。

Vizgen is poised to redefine the standards of spatial genomics with the advancements of MERSCOPE Ultra paired with the future integration of the MERFISH 2.0 chemistry.

随着MERSCOPE Ultra的进步以及MERFISH 2.0化学的未来整合，Vizgen准备重新定义空间基因组学的标准。

About Vizgen®

关于Vizgen®

Vizgen is dedicated to pioneering the next generation of genomics, providing tools that demonstrate the possibilities of in situ single-cell spatial genomics. The company has established the benchmark in spatial genomics and continues to drive industry innovation, delivering the highest sensitivity as well as excellent specificity and accuracy in cell segmentation.

Vizgen致力于开创下一代基因组学，提供证明原位单细胞空间基因组学可能性的工具。。

Vizgen’s MERSCOPE® Platform provides transformative insight into a wide range of tissue-scale basic research and translational medicine in oncology, immunology, neuroscience, infectious disease, developmental biology, cell and gene therapy, and is an essential tool for accelerating drug discovery and development.

Vizgen的MERSCOPE®平台为肿瘤学、免疫学、神经科学、传染病、发育生物学、细胞和基因治疗等领域的广泛组织规模基础研究和转化医学提供了革命性的见解，是加速药物发现和开发的重要工具。

For more information, go to www.vizgen.com. Connect on social media Twitter, LinkedIn, and Facebook..

有关更多信息，请访问www.vizgen.com。连接社交媒体Twitter、LinkedIn和Facebook。。