牙科团队可以帮助检测患者中未确诊的糖尿病-动脉网

Dental teams could help detect undiagnosed diabetes in patients

Dental Tribune 等信源发布 2024-09-25 15:31

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Dental Tribune International

国际牙科论坛

Wed. 25. September 2024

周三。

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BIRMINGHAM, England: Diabetes is one of the most common chronic conditions in Europe and is strongly associated with periodontitis. An estimated one in three people with diabetes are undiagnosed, totalling more than one million undiagnosed patients in the UK alone. Seeking to help improve diagnosis of Type 2 diabetes in such patients, researchers in the UK are working on a new study, called INDICATE-2, to validate routine diabetes screening during oral health check-ups..

英国伯明翰：糖尿病是欧洲最常见的慢性病之一，与牙周炎密切相关。据估计，三分之一的糖尿病患者未确诊，仅在英国就有100多万未确诊患者。为了帮助改善此类患者对2型糖尿病的诊断，英国研究人员正在进行一项名为DIRECT-2的新研究，以验证口腔健康检查期间的常规糖尿病筛查。。

The study, being conducted by researchers at the University of Birmingham, has received funding from Haleon, a global consumer health company, and the support of the UK’s National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre.

这项由伯明翰大学研究人员进行的研究得到了全球消费者健康公司Haleon的资助，以及英国国家健康与保健研究所（NIHR）伯明翰生物医学研究中心的支持。

“This exciting collaboration with Haleon will allow us to determine the actual prevalence of prediabetes and Type 2 diabetes within a larger, more representative population sample and assess the feasibility of scaling this approach nationally. It will explore the patient journey and identify barriers or challenges in the care pathway,” co-researcher Dr Zehra Yonel, a clinical lecturer in periodontics in the School of Dentistry at the University of Birmingham, said in a press release..

伯明翰大学牙科学院牙周病临床讲师Zehra Yonel博士在新闻稿中说：“与Haleon的这项令人兴奋的合作将使我们能够在更大、更具代表性的人群样本中确定糖尿病前期和2型糖尿病的实际患病率，并评估在全国推广这种方法的可行性。它将探索患者的旅程，并确定护理途径中的障碍或挑战。”。。

In a 2023 study, the Birmingham researchers collaborated with others from the universities of Leicester and Oxford in the UK and the University of Greifswald in Germany to develop the Diabetes Risk Assessment in Dentistry Score (DDS), a tool designed to help identify prediabetes and diabetes in dental settings.

在2023年的一项研究中，伯明翰研究人员与英国莱斯特大学和牛津大学以及德国格雷夫斯瓦尔德大学的其他研究人员合作，开发了牙科糖尿病风险评估评分（DDS），该工具旨在帮助识别牙科环境中的糖尿病前期和糖尿病。

The DDS was recently used in a pilot study, which was funded by NIHR and Diabetes UK and conducted across 13 dental practices with 805 participants. For participants whose DDS scores indicated that they may have prediabetes or diabetes, the haemoglobin A1c finger prick test was administered, and the trial found that nearly 15% of the participants who considered themselves healthy exceeded the UK’s prediabetes or diabetes threshold score on this test..

DDS最近被用于一项试点研究，该研究由NIHR和英国糖尿病协会资助，在13个牙科诊所进行，共有805名参与者。对于DDS评分表明可能患有糖尿病前期或糖尿病的参与者，进行了血红蛋白A1c手指点刺试验，该试验发现，近15%认为自己健康的参与者在该试验中超过了英国糖尿病前期或糖尿病阈值评分。。

Based on this pilot study, INDICATE-2 will work with 50 dental practices across England and Scotland to screen more than 10,000 patients and develop a care pathway that could help dental services detect people with undiagnosed diabetes in the UK and refer them for treatment.

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Co-lead researcher for INDICATE-2 Dr Iain Chapple, professor of periodontics at the University of Birmingham’s School of Dentistry, said: “This funding from Haleon is very exciting, as it will enable us to validate the two-step model on patients routinely attending dental practices across the UK and test onward referral pathways of high-risk patients to their family doctors for diagnosis and treatment.”.

伯明翰大学牙科学院牙周病学教授Iain Chapple博士是DIRECT-2的联合首席研究员，他说：“Haleon的这项资助非常令人兴奋，因为它将使我们能够验证英国常规牙科诊所患者的两步模型，并测试高危患者向其家庭医生的转诊途径以进行诊断和治疗。”。

Dr Jason Wong, MBE, chief dental officer for England, said: “It is vitally important that medical and dental care pathways become more joined up, to put patients at the centre of all we do. INDICATE-2 is a great example of a study aimed to try and define one such pathway.”

英国首席牙科官Jason Wong博士表示：“医疗和牙科护理途径更加紧密地结合起来，将患者置于我们所有工作的中心，这一点至关重要。DIRECT-2是一个很好的例子，旨在尝试定义一种这样的途径。”

Adam Sisson, head of research and development in oral health at Haleon, concluded: “We are delighted to be collaborating with the University of Birmingham and NIHR to help support this important scientific research. We hope the findings will underpin a new care pathway aimed at proactively identifying and treating more people with diabetes by leveraging the expertise of oral health professionals.

Haleon口腔健康研究与发展负责人Adam Sisson总结道：“我们很高兴与伯明翰大学和NIHR合作，帮助支持这项重要的科学研究。我们希望这些发现将支持一种新的护理途径，旨在通过利用口腔健康专业人员的专业知识，积极识别和治疗更多的糖尿病患者。

The study will also help to draw further attention to the links between our oral and systemic health.”.

这项研究还将有助于进一步关注我们的口腔和全身健康之间的联系。”。

Topics:

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General Dentistry

普通牙科

Diagnostics

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Dental research

牙科研究

Dental screening

牙科筛查

Diabetes

糖尿病

Oral health

口腔健康

Periodontitis

牙周炎

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