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MADISON, Wis.--(BUSINESS WIRE)--Promega Corporation, a life-sciences research partner dedicated to providing intuitive tools that empower scientists to innovate, today unveils the new GloMax® Galaxy Bioluminescence Imager being showcased at the annual Society for Neuroscience (SFN) 2024 conference in Chicago October 5-9..
威斯康星州麦迪逊市。-(商业新闻短讯)--Promega Corporation是一家生命科学研究合作伙伴,致力于提供直观的工具,使科学家能够创新,今天推出了新的GloMax®Galaxy生物发光成像仪,该成像仪将于10月5日至9日在芝加哥举行的2024年年度神经科学学会(SFN)会议上展出。。
The GloMax® Galaxy Bioluminescence Imager provides researchers the opportunity to observe the dynamics and cellular physiology of low expression protein targets in real time. This advanced microscope is developed for the visualization of Promega NanoLuc® luciferase chemistries, eliminating the complex process of translating bioluminescent reporter assays into fluorescence..
GloMax®Galaxy生物发光成像仪为研究人员提供了实时观察低表达蛋白靶标的动力学和细胞生理学的机会。这种先进的显微镜是为可视化Promega NanoLuc®荧光素酶化学而开发的,消除了将生物发光报告分析转化为荧光的复杂过程。。
“Researchers are no longer required to translate their assay biology into a fluorescent reporter system to enable imaging. They can use the same NanoLuc-based technologies that they’ve been using in plate-based assay readouts,” says Kristin Riching, Sr Research Scientist at Promega.
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GloMax® Galaxy Bioluminescence Imager
GloMax®银河生物发光成像仪
GloMax® Galaxy Bioluminescence Imager is a benchtop instrument developed for the visualization of all NanoLuc® technologies, including HiBiT, NanoBiT and NanoBRET. The technology allows researchers to use the same bioluminescent reporter used in other parts of their workflow. Applications include:
GloMax®Galaxy生物发光成像仪是一种台式仪器,用于可视化所有NanoLuc®技术,包括HiBiT、NanoBiT和NanoBRET。该技术允许研究人员使用与工作流程其他部分相同的生物发光报告器。应用包括:
Protein-protein interactions
蛋白质-蛋白质相互作用
Protein localization and translocation
蛋白质定位和易位
Protein degradation and stability
蛋白质降解和稳定性
Ligand-protein interactions (target engagement)
配体-蛋白质相互作用(目标参与)
Targeted cell killing
靶向细胞杀伤
Bioluminescence imaging offers several advantages over fluorescence imaging. The system produces low background noise, enabling the detection of low photon numbers and low abundance proteins. Unlike fluorescence imaging, which requires external excitation, bioluminescence benefits from inherent signal stability and sustainability.
生物发光成像比荧光成像具有几个优点。该系统产生低背景噪声,能够检测低光子数和低丰度蛋白质。与需要外部激发的荧光成像不同,生物发光受益于固有的信号稳定性和可持续性。
Improved signals reduce the risk of phototoxicity and photobleaching, allowing for repeated imaging sessions over extended periods without damaging the cells or altering the physiological state. Implementing bioluminescence imaging in a workflow enhances disease modeling and pharmaceutical candidate screening efforts by providing clearer, real-time insights into how cells and proteins behave in biological systems..
改进的信号降低了光毒性和光漂白的风险,允许长时间重复成像,而不会损坏细胞或改变生理状态。通过在工作流程中实施生物发光成像,可以更清晰、实时地了解细胞和蛋白质在生物系统中的行为,从而增强疾病建模和候选药物筛选工作。。
Promega Instrumentation Portfolio
Promega仪器组合
GloMax® Galaxy Bioluminescence Imager joins an existing portfolio of detection instruments developed by Promega. GloMax® microplate readers and luminometers are capable of measuring luminescence, fluorescence, absorbance, bioluminescence resonance energy transfer (BRET) and fluorescence resonance energy transfer (FRET) at a range of throughputs..
GloMax®Galaxy生物发光成像仪加入了Promega开发的现有检测仪器组合。GloMax®酶标仪和光度计能够在一定范围内测量发光、荧光、吸光度、生物发光共振能量转移(BRET)和荧光共振能量转移(FRET)。。
Promega creates intuitive tools that solve complex research problems, while leveraging a range of the simplest to the most cutting-edge technology to ensure practical ease of use and effectiveness. The company’s creative solutions and flexible technologies are designed to address complex scientific challenges, enabling researchers to make meaningful advances in their fields..
Promega创建直观的工具来解决复杂的研究问题,同时利用一系列最简单到最前沿的技术来确保实际的易用性和有效性。该公司的创造性解决方案和灵活的技术旨在应对复杂的科学挑战,使研究人员能够在其领域取得有意义的进步。。
Promega invites attendees of SFN 2024 to Booth #1316 to experience live demonstrations of the Glomax® Galaxy, showcasing its potential to transform research.
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Learn more about GloMax® Galaxy Bioluminescence Imager here.
在此了解有关GloMax®Galaxy生物发光成像仪的更多信息。
About Promega Corporation
关于Promega Corporation
Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company’s portfolio of over 4,000 products supports a range of life science work across areas such as cell biology; DNA, RNA and protein analysis; drug development; human identification and molecular diagnostics.
Promega Corporation是为生命科学行业提供创新解决方案和技术支持的领导者。该公司拥有4000多种产品,支持细胞生物学等领域的一系列生命科学工作;DNA,RNA和蛋白质分析;药物开发;。
These tools and technologies have grown in their application over the last 45 years and are used today by scientists and technicians in labs for academic and government research, forensics, pharmaceuticals, clinical diagnostics and veterinary, agricultural and environmental testing. Promega is headquartered in Madison, WI, USA with branches in 16 countries and over 50 global distributors.
这些工具和技术在过去45年的应用中不断发展,如今被实验室的科学家和技术人员用于学术和政府研究、法医学、制药、临床诊断以及兽医、农业和环境测试。Promega总部位于美国威斯康星州麦迪逊,在16个国家设有分支机构,在全球拥有50多家分销商。
Learn more at www.promega.com..
更多信息,请访问www.promega.com。。