VANCOUVER, Canada--(BUSINESS WIRE)--Following its successful fundraising of C$4.91 million (US$3.62), Canadian life sciences company Ondine Biomedical Inc. will continue accelerating commercialisation of its proven nasal photodisinfection technology. This cutting-edge technology replaces topical antibiotics for the prevention of healthcare-associated infections (HAIs) and kills all types of pathogens – bacteria, viruses and fungi – without causing antimicrobial resistance..

加拿大温哥华--（商业新闻短讯）--加拿大生命科学公司Ondine Biomedical Inc.成功筹集491万加元（3.62美元）资金后，将继续加速其经验证的鼻光感染技术的商业化。这项尖端技术取代了用于预防医疗保健相关感染（HAIs）的局部抗生素，并杀死了所有类型的病原体-细菌，病毒和真菌-而不会产生抗菌药物耐药性。。

The company has confirmed that it has more than doubled the number of Steriwave® deployments in 2023 and is in discussions with more than 75 hospitals in the UK, Mexico, Spain, and Canada. The growing global focus on preventing HAIs post-surgery, coupled with the escalating challenge of antimicrobial resistance, has spurred heightened interest in Ondine’s photodisinfection technology..

该公司已证实，2023年Steriwave®部署数量增加了一倍多，目前正在与英国、墨西哥、西班牙和加拿大的75多家医院进行讨论。全球越来越关注预防术后HAIs，加上抗菌素耐药性的挑战不断升级，引发了人们对Ondine光感染技术的兴趣。。

The deployments are in areas of major surgery, including spinal, orthopedic, and cardiovascular. The antibiotic mupirocin has been used for nasal decolonization for the prevention of HAIs since the 1980s. However, mupirocin has resistance rates of up to 81%,2 and very poor compliance.3

部署在大手术领域，包括脊柱，骨科和心血管。自20世纪80年代以来，抗生素莫匹罗星已被用于鼻腔非殖民化以预防HAI。然而，莫匹罗星的耐药率高达81%，2并且依从性很差。3

Carolyn Cross, CEO of Ondine, commented, 'We have put great efforts into improving our commercial activity sales process, which has increased the speed of the average sales cycle from contact to deployment by 50%. We have appointed distributors in the UK, Spain, and Mexico and are gaining real momentum.

Ondine首席执行官卡罗琳·克罗斯（CarolynCross）评论道：“我们已经付出了巨大的努力来改进我们的商业活动销售流程，这使从联系到部署的平均销售周期速度提高了50%。我们已经在英国、西班牙和墨西哥指定了经销商，并且正在获得真正的动力。

What is particularly encouraging is that many hospitals are recommending Steriwave to other hospitals. We believe this momentum will continue to increase, and commercial sales will become more significant in 2024.”.

特别令人鼓舞的是，许多医院正在向其他医院推荐Steriwave。我们相信这一势头将继续增强，2024年商业销售将变得更加重要。”。

The five-minute Steriwave nasal decolonization procedure is easy to incorporate into the pre surgery procedures. It is painless and very well received by patients who are often intrigued by the process. There have been no reports of serious side effects as a result of Steriwave usage. Steriwave has been used by more than 150,000 patients, including at Vancouver General Hospital where its use has been associated with a significant reduction in HAIs across major surgeries.4,5.

五分钟的Steriwave鼻腔非殖民化程序很容易纳入手术前程序。它是无痛的，并且受到经常对此过程感兴趣的患者的欢迎。没有关于使用Steriwave导致严重副作用的报道。Steriwave已经被超过150000名患者使用，包括在温哥华总医院，它的使用与大手术中HAIs的显着减少有关[4,5]。

As well as growing its commercial activities, the company continues to work closely with HCA – the largest hospital group in the United States – to prepare for the Phase 3 trial in circa 14 HCA hospitals as part of its Ondine’s submission to the FDA for approval. The company already has approval for Steriwave in Canada, the UK, the EU, and Mexico..

除了扩大其商业活动外，该公司还继续与美国最大的医院集团HCA密切合作，为大约14家HCA医院的3期试验做准备，作为其Ondine提交FDA批准的一部分。该公司已在加拿大、英国、欧盟和墨西哥获得Steriwave的批准。。

Implementing nasal decolonization prior to major surgery to reduce HAIs is recommended by leading medical bodies, including the World Health Organization,6 the Society for Healthcare Epidemiology of America (SHEA),7 and NICE.8 The nose is the major reservoir of pathogens and the majority of surgical site infections (SSIs) and bloodstream infections have been traced back to bacteria in the patient’s nose.9 A patient with a surgical site infection (SSI) will, on average, spend 7 to 11 days longer in the hospital, significantly increasing costs and lengthening patients' recovery.10.

主要医疗机构建议在大手术前实施鼻腔非殖民化以减少HAI，包括世界卫生组织，6美国医疗保健流行病学协会（SHEA），7和尼斯。8鼻子是病原体的主要储存库，大多数手术部位感染（SSI）和血流感染可追溯到患者鼻子中的细菌。9患有手术部位感染（SSI）的患者平均住院时间延长7至11天，大大增加了成本，延长了患者的康复时间。

While currently focusing on nasal decolonization, Ondine’s patented photodisinfection technology will be developed to prevent and treat a wide variety of topical infections.

虽然目前专注于鼻腔非殖民化，但Ondine的专利光感染技术将被开发用于预防和治疗各种局部感染。

About Ondine Biomedical Inc.

关于Ondine Biomedical Inc。

Ondine Biomedical Inc. is a Canadian life science company pioneering the field of photodisinfection therapies. Ondine has a pipeline of investigational products, based on its proprietary photodisinfection platform, in various stages of development. Products beyond nasal photodisinfection include therapies for a variety of medical indications such as chronic sinusitis, ventilator-associated pneumonia, burns, and other indications..

Ondine Biomedical Inc.是一家加拿大生命科学公司，在光感染治疗领域处于领先地位。Ondine基于其专有的photodisinfection平台，在不同的开发阶段拥有一系列研究产品。鼻光感染以外的产品包括各种医学适应症的治疗，如慢性鼻窦炎、呼吸机相关性肺炎、烧伤和其他适应症。。

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