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XtalPi旗下的Ailux Biologics与杨森生物技术公司就生物制品人工智能平台签订许可协议

Ailux Biologics, a Division of XtalPi, Enters into a License Agreement with Janssen Biotech on Biologics AI Platform

PHARMA FOCUS ASIA 等信源发布 2024-10-11 15:41

可切换为仅中文


XtalPi, a global leader in AI drug discovery, announced today a license agreement between Ailux Biologics, a division of XtalPi Inc., and Janssen Biotech, Inc.,(Janssen) a Johnson & Johnson company, on one of its proprietary biologics AI platforms. Under the agreement, Ailux Biologics grants Janssen and its affiliates a non-exclusive license to leverage its XtalFold™ platform for the discovery and engineering of biologics.

人工智能药物发现的全球领导者XtalPi今天宣布,XtalPi Inc.旗下的Ailux Biologics与强生公司Janssen Biotech,Inc.(Janssen)就其专有生物制剂人工智能平台之一达成了许可协议。。

XtalFold™ is a proprietary AI-based software suite that provides rapid and accurate structural insights to accelerate biologics innovation across multiple phases. The agreement was facilitated by Johnson & Johnson Innovation.XtalFold™ utilizes sequence information alone to model the interaction between biomolecules, which forms the foundation of biotherapeutics like monoclonal antibodies.

XtalFold™是一个专有的基于人工智能的软件套件,可提供快速准确的结构见解,以加速生物制剂在多个阶段的创新。该协议由强生创新促进。XtalFold™仅利用序列信息来模拟生物分子之间的相互作用,这构成了生物治疗药物(如单克隆抗体)的基础。

In rigorous benchmark studies, XtalFold™ achieved state-of-the-art performance in terms of overall success rate and the quality of hard-to-model regions like the antibody-antigen interface. Since its launch one year ago, XtalFold™ has been fully validated in more than 30 partner and internal programs, delivering highly impactful results in a variety of use cases, including antigen design, epitope identification, affinity maturation, pH-sensitivity engineering, and bispecifics design.Yi (Alex) Li, VP of XtalPi and Head of Ailux Biologics, said: 'Biologics are intricate machines that operate in three-dimensional space.

在严格的基准研究中,XtalFold™在总体成功率和抗体-抗原界面等难以建模区域的质量方面取得了最先进的性能。自一年前推出以来,XtalFold™已在30多个合作伙伴和内部程序中得到充分验证,在各种用例中提供了极具影响力的结果,包括抗原设计,表位鉴定,亲和力成熟,pH敏感性工程和双特异性设计。XtalPi副总裁兼爱力士生物制品公司负责人李毅(Alex)说:“生物制品是在三维空间中运行的复杂机器。

XtalFold™ enables the visualization and design of biologics in 3D space in real time, which could take months using currently available experimental approaches. We are excited to share with Janssen this foundational technology, which has already proven transformative in-house.'About XtalPiXtalPi ('QuantumPharm Inc.', stock code: 2228.HK) is a quantum phy.

XtalFold™能够实时在3D空间中可视化和设计生物制剂,使用目前可用的实验方法可能需要数月的时间。我们很高兴与杨森分享这项基础技术,这项技术在内部已经证明具有变革性。”关于XtalPiXtalPi(“QuantumPharm Inc.,股票代码:2228.HK”)是一种量子物理。