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register hereVersion July 19October 17, 2024 vitreal level of dopamine metabolites. Retinal EGR-1 mRNA level was positively correlated with choroidal thickness. Retinal OPN4 melanopsin mRNA was increased by 10 Hz-ON stimulation and choroidal BMPR1A mRNA increased with 10 Hz-OFF stimulation. Averaged overOn average all experiments, early choroidal thinning did not predict the amount of negative lens-induced eye growth changes after 7 days, whereas later ChT changes showed a weak association.Negative lenses caused long-lasting choroidal thinning, with some recovery during lens wear, especially after stimulation with 10 Hz.The dynamic stimuli modulated choroidal thinning but effects were small.There was little difference between ON and OFF stimulation, perhaps because the checkerboard patterns were too coarse.

在此注册2024年7月19日至10月17日玻璃体多巴胺代谢物水平。视网膜EGR-1 mRNA水平与脉络膜厚度呈正相关。视网膜OPN4黑视蛋白mRNA在刺激时增加10 Hz，脉络膜BMPR1A mRNA在10 Hz OFF刺激时增加。平均而言，在所有实验中，早期脉络膜变薄并不能预测7天后负面晶状体诱导的眼睛生长变化的数量，而后来的ChT变化显示出较弱的关联。负镜片会导致脉络膜长期变薄，在镜片磨损过程中会有所恢复，尤其是在用10 Hz刺激后。动态刺激调节脉络膜变薄，但影响很小。开和关刺激之间几乎没有差异，可能是因为棋盘格模式太粗糙了。

10 Hz cycle frequency increased dopamine release. Less dopamine was correlated with thinner choroids. Result do not exclude a predictive value of choroidal thickeningChT for future refractive development since we almost exclusively tested choroidal thinning effects..

。较少的多巴胺与较薄的脉络膜相关。结果不排除脉络膜增厚对未来屈光发展的预测价值，因为我们几乎只测试了脉络膜变薄的影响。。