AbstractBody weight gain is a prevalent adverse effect observed in psychiatric medication therapy. With the notable increase in mental health diagnoses among children and adolescents over the last decade, exacerbated by the COVID-19 pandemic, the use of medications associated with weight gain poses an additional risk for obesity development.

摘要体重增加是精神药物治疗中普遍存在的不良反应。随着过去十年来儿童和青少年心理健康诊断的显着增加，新型冠状病毒（COVID-19）大流行加剧了这种情况，与体重增加相关的药物的使用为肥胖的发展带来了额外的风险。

This study aimed to identify psychiatric drugs that may induce weight gain in children as a side effect. Twenty-nine publications were included in this systematic review, investigating the effects of nineteen different drugs on children’s weight. The majority of these drugs belonged to atypical antipsychotics and anticonvulsants.

这项研究旨在确定可能导致儿童体重增加的精神药物作为副作用。。这些药物中的大多数属于非典型抗精神病药和抗惊厥药。

Nearly all included articles reported that the examined substances resulted in weight gain in children. As childhood obesity has become a significant problem with various metabolic, psychological and social consequences, it is crucial to carefully consider therapy options. In addition to evaluating effectiveness, it is important to also assess the potential for weight gain.

几乎所有纳入的文章都报告说，被检查的物质导致儿童体重增加。由于儿童肥胖已成为具有各种代谢，心理和社会后果的重大问题，因此仔细考虑治疗方案至关重要。除了评估有效性外，重要的是还要评估体重增加的可能性。

Clinicians and nutrition specialists should individually evaluate patients’ nutritional needs, evaluate obesity risk, and provide appropriate dietary guidance to minimalize the risk of weight gain..

临床医生和营养专家应单独评估患者的营养需求，评估肥胖风险，并提供适当的饮食指导，以尽量减少体重增加的风险。。

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Fig. 1: PRISMA flow diagram.

图1:PRISMA流程图。

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Download referencesAuthor informationAuthors and AffiliationsDepartment of Pharmacology, Medical University of Gdańsk, Dębowa 23, 80-204, Gdańsk, PolandKarolina Kuźbicka, Iga Pawłowska & Ivan KocićAuthorsKarolina KuźbickaView author publicationsYou can also search for this author in

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PubMed Google ScholarContributionsKarolina Kuźbicka contributed to the conception of the study, the statistical design, analysis, collected the data, interpreted the data, reviewed the literature, wrote the manuscript and revised the content. Iga Pawłowska contributed to the conception of the study, analysis, data interpretation and revised the content.

PubMed谷歌学术贡献Karolina Kuźbicka为研究的概念，统计设计，分析，收集数据，解释数据，审查文献，撰写手稿并修订内容做出了贡献。Iga Pawłowska为研究，分析，数据解释的概念做出了贡献，并修订了内容。

Ivan Kocić critically reviewed the content. All authors reviewed the manuscript and provided final approval of the version to be published.Corresponding authorCorrespondence to.

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Additional informationPublisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.Rights and permissionsSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.Reprints and permissionsAbout this articleCite this articleKuźbicka, K., Pawłowska, I.

。权利和许可Pringer Nature或其许可人（例如协会或其他合作伙伴）根据与作者或其他权利持有人的出版协议对本文拥有专有权；本文接受稿件版本的作者自行存档仅受此类出版协议和适用法律的条款管辖。转载和许可本文引用本文Kuźbicka，K.，Pawłowska，I。

& Kocić, I. Drugs used in psychiatry causing an increase in body weight in children—a review..

&Kocić，I.精神病学中使用的导致儿童体重增加的药物-综述。。

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