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register herePurpose: This study aimed to investigate the effect of lumbar multifidus muscle(MF) degeneration on upper lumbar disc herniation(ULDH).Methods: This study used 3.0T magnetic resonance imaging(MRI)T2 axial weighted images to retrospectively analyze 93 ULDH patients and 111 healthy participants.

注册目的：本研究旨在探讨腰椎多裂肌（MF）退变对上腰椎间盘突出症（ULDH）的影响。方法：本研究使用3.0T磁共振成像（MRI）T2轴向加权图像回顾性分析93例ULDH患者和111例健康参与者。

Sixty-five pairs of participants were included in this study using propensity score matching(PSM). Cross-sectional area, fat infiltration area, anteroposterior diameter(APD), lateral diameter(LD), cross-sectional area of the bilateral multifidus muscles at the corresponding level, intervertebral disc area at the corresponding section, and visual analog scale(VAS) score for low back pain(LBP).

使用倾向评分匹配（PSM）将65对参与者纳入本研究。横截面积，脂肪浸润面积，前后径（APD），侧径（LD），相应水平双侧多裂肌的横截面积，相应部分的椎间盘面积和视觉模拟评分（VAS）评分腰痛（LBP）。

For inter-group comparisons, we used the t-test, analysis of variance(ANOVA), Mann-Whitney U test, Kruskal-Wallis test, chi-square test, or Fisher's exact test, according to the type of data. We used Pearson correlation analysis to study the correlation between the VAS score and related indicators, and established a predictive model for upper lumbar disc herniation using the receive operative characteristic(ROC) curve analysis method.

对于组间比较，我们根据数据类型使用t检验，方差分析（ANOVA），Mann-Whitney U检验，Kruskal-Wallis检验，卡方检验或Fisher精确检验。我们使用Pearson相关分析来研究VAS评分与相关指标之间的相关性，并使用ROC曲线分析方法建立了上腰椎间盘突出症的预测模型。

Finally, univariate and multivariate logistic regression analyses were performed to establish a predictive model for the risk of high lumbar disc herniation.Results: We compared the fat areas at the lumbar vertebral levels L1/2, L2/3, and L3/4, as well as the left lateral diameter(LD)(MF), L1/2 left lumbar multifidus muscle index(LMFI), and L1/2 total fat infiltration cross-section area(TFCSA), and found significant differences between the case and control groups(P < 0.001).

最后，进行单因素和多因素logistic回归分析，以建立高腰椎间盘突出症风险的预测模型。结果：我们比较了腰椎L1/2，L2/3和L3/4水平的脂肪面积，以及左侧外径（LD）（MF），L1/2左腰椎多裂肌指数（LMFI）和L1/2总脂肪浸润横截面积（TFCSA），发现病例组和对照组之间存在显着差异（P＜0.001）。

Furthermore, we observed a significant positive correlation(P < 0.05) between the VAS scores and multiple muscle indicators. Additionally, we developed ROC prediction mo.

此外，我们观察到VAS评分与多种肌肉指标之间存在显着的正相关（P＜0.05）。。