What You Should Know:

您应该知道：

– A new cancer treatment and research era is dawning in Japan with the launch of LC-SCRUM-CD (Lung Cancer Genome Screening Project for Individualized Medicine – Clinical Development).

–随着LC-SCRUM-CD（个体化医学肺癌基因组筛查项目-临床开发）的推出，日本正在迎来一个新的癌症治疗和研究时代。

– The nationwide clinical trial network is a collaborative effort between the National Cancer Center (NCC), Precision Medicine Asia Co., Ltd. (PREMIA), and Paradigm Health Inc. (Paradigm).

–全国临床试验网络是国家癌症中心（NCC）、亚洲精准医学有限公司（PREMIA）和Paradigm Health Inc.（Paradigm）之间的合作成果。

Building on LC-SCRUM-Asia’s Foundation

建立在LC SCRUM Asia的基础上

LC-SCRUM-CD expands upon the existing LC-SCRUM-Asia network, which comprises over 150 hospitals and boasts extensive cancer genomic screening capabilities.This foundation will be instrumental in driving clinical trials focused on precision medicine, tailoring treatments to individual patients based on their genetic makeup..

LC-SCRUM-CD扩展了现有的LC-SCRUM亚洲网络，该网络由150多家医院组成，拥有广泛的癌症基因组筛查能力。该基金会将有助于推动专注于精准医学的临床试验，根据患者的基因构成为个体患者量身定制治疗方法。。

A Collaborative Approach to Advance Precision Medicine

推进精准医学的合作方法

The collaboration between NCC, PREMIA, and Paradigm brings together expertise and resources. NCCHE (National Cancer Center Hospital East), a leader in clinical trials in Japan, will play a pivotal role in the network. PREMIA, with its expertise in data management, will oversee the network’s data platform, integrating vast amounts of genetic and clinical data to efficiently identify potential clinical trial candidates. .

NCC、PREMIA和Paradigm之间的合作汇集了专业知识和资源。日本临床试验的领导者NCCHE（National Cancer Center Hospital East）将在该网络中发挥关键作用。PREMIA凭借其在数据管理方面的专业知识，将监督该网络的数据平台，整合大量的遗传和临床数据，以有效识别潜在的临床试验候选人。。

Paradigm’s Innovative Approach to Clinical Trials

Paradigm的临床试验创新方法

Paradigm Health brings its innovative, end-to-end clinical trial platform to the network. This platform is designed to streamline clinical trial processes, reducing the burden on physicians and hospital staff while expanding patient trial access. Paradigm’s success in working with rural and community-based health systems in the US will inform the design and operation of LC-SCRUM-CD, ensuring broader reach and accessibility..

Paradigm Health将其创新的端到端临床试验平台引入网络。该平台旨在简化临床试验流程，减轻医生和医院工作人员的负担，同时扩大患者的试验访问。Paradigm与美国农村和社区卫生系统合作的成功将为LC-SCRUM-CD的设计和运营提供信息，确保更广泛的覆盖范围和可访问性。。

Benefits of the LC-SCRUM-CD Network

LC-SCRUM-CD网络的好处

Increased Efficiency: Streamlined processes and workflows will make it more efficient for pharmaceutical companies to conduct clinical trials in Japan.Expanded Access: More patients across the LC-SCRUM-Asia network will have access to a wider range of clinical trial options.Reduced Burden: Paradigm’s platform will significantly reduce the time and burden on clinical staff involved in trials.Improved Outcomes: By promoting precision medicine and expanding access to clinical trials, LC-SCRUM-CD has the potential to significantly improve patient outcomes..

提高效率：简化流程和工作流程将提高制药公司在日本进行临床试验的效率。扩大访问范围：LC SCRUM Asia网络中的更多患者将获得更广泛的临床试验选择。减轻负担：Paradigm的平台将大大减少参与试验的临床工作人员的时间和负担。改进的结果：通过推广精准医学和扩大临床试验的机会，LC-SCRUM-CD有可能显着改善患者的预后。。

“NCCHE is a world-renowned hospital and research institution, where patients from across Japan come to receive care,” Dr Goto, a deputy director and the chief of department of thoracic oncology at NCCHE and the representative of LC-SCRUM-Asia, said. “Working with our partners at PREMIA and Paradigm, we will fully utilize this expertise in clinical trial operations, allowing all patients who are taking part in LC-SCRUM-Asia to benefit from personalized access to the breadth of clinical trials being run by global biopharmaceutical sponsors at the same time as the US.”.

“NCCHE是一家世界知名的医院和研究机构，来自日本各地的患者都来这里接受治疗，”NCCHE副主任兼胸肿瘤科科长、LC SCRUM Asia代表Goto博士说。“与PREMIA and Paradigm的合作伙伴合作，我们将在临床试验操作中充分利用这一专业知识，使所有参加LC SCRUM Asia的患者都能从全球生物制药赞助商与美国同时进行的广泛临床试验中受益。”。