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青少年特发性脊柱侧凸冠状楔形畸形与矢状面脊柱曲度的相关性:回顾性分析

Correlation between coronal wedge deformity and sagittal spinal curvature in adolescent idiopathic scoliosis: a retrospective analysis

Nature 等信源发布 2024-11-23 18:54

可切换为仅中文


AbstractThe correlation between the Cobb angle and the sagittal spinal curvature (SSC) in adolescent idiopathic scoliosis (AIS) has been reported in some previous studies, but few studies have reported on the relation of coronal wedge deformity (CWD) with sagittal curvature. This study aims to investigate the correlation between CWD and SSC in AIS patients.

青少年特发性脊柱侧凸(AIS)的Cobb角与矢状脊柱曲率(SSC)之间的相关性已有报道,但关于冠状楔状畸形(CWD)与矢状曲率之间关系的研究很少。本研究旨在探讨AIS患者CWD与SSC之间的相关性。

A retrospective analysis was conducted in 122 AIS patients treated at our hospital from January 2018 to November 2023. Correlation analysis was performed on the Cobb angle, total wedge angle(TW), apical vertebral wedge angle (APW), upper end-vertebral wedge angle (UW), lower end-vertebral wedge angle (LW), total affected structures, average wedge angle(AW), total vertebral wedge angle (TVW), average vertebral wedge angle (AVW), Vertebral Wedge Angle ratio (VWR), total disc wedge angle (TDW), average disc wedge angle (ADW), and disc wedge angle ratio (DWR).

。对Cobb角,总楔角(TW),顶端椎体楔角(APW),上端椎体楔角(UW),下端椎体楔角(LW),总受累结构,平均楔角(AW),总椎体楔角(TVW),平均椎体楔角(AVW),椎体楔角比(VWR),总椎间盘楔角(TDW),平均椎间盘楔角(ADW)和椎间盘楔角比(DWR)进行相关性分析。

Furthermore, out of all cases which underwent lateral spinal radiographs, a correlation analysis between thoracic kyphosis (TK), lumbar lordosis (LL) and CWD was carried out on 102 patients. The Cobb angle exhibited a significant positive correlation with multiple CWD parameters (P < 0.05). TK showed a significant negative correlation with the Cobb angle (r = − 0.221, P = 0.026), TW (r = − 0.199, P = 0.045), AW (r = − 0.262, P = 0.008), TDW (r = − 0.211, P = 0.033), and ADW (r = − 0.278, P = 0.005).

此外,在所有接受脊柱侧位X线检查的病例中,对102例患者进行了胸椎后凸(TK),腰椎前凸(LL)和CWD之间的相关性分析。Cobb角与多个CWD参数呈显着正相关(P<0.05)。。

LL had no significant correlation with TK and other parameters (P > 0.05). In mild and moderate AIS patients, CWD parameters were positively correlated with the Cobb angle and negatively correlated with thoracic SSC. This may indicate that it’s necessary to correct sagittal thoracic curvature when rectifying scoliosis in clinic.

LL与TK和其他参数无显着相关性(P>0.05)。在轻度和中度AIS患者中,CWD参数与Cobb角呈正相关,与胸部SSC呈负相关。这可能表明在临床矫正脊柱侧凸时有必要矫正胸廓矢状曲度。

This research would not only provide new .

IntroductionAdolescent idiopathic scoliosis (AIS) stands as one of the most common spinal deformities among adolescents, with an estimated prevalence ranging from 2 to 3% within this demographic1. Beyond merely affecting posture, AIS can lead to significant complications, including respiratory limitations, chronic pain, and psychological challenges2,3,4,5.

引言青少年特发性脊柱侧凸(AIS)是青少年中最常见的脊柱畸形之一,在该人口统计学中估计患病率为2%至3%1。除了仅仅影响姿势外,AIS还可能导致严重的并发症,包括呼吸受限,慢性疼痛和心理挑战2,3,4,5。

The Cobb angle remains the gold standard for assessing scoliosis severity, but it is essential to recognize that the spine undergoes complex alterations across the transverse, sagittal, and coronal planes as AIS progresses. The previous studies had increasingly focused on coronal plane wedge deformities in AIS patients; however, much of this work tended to examine parameters in isolation, often overlooking the critical relationships between coronal wedge deformity and changes in sagittal physiological curvatures6,7,8.

Cobb角仍然是评估脊柱侧弯严重程度的金标准,但必须认识到,随着AIS的进展,脊柱在横向,矢状面和冠状面上会发生复杂的变化。先前的研究越来越关注AIS患者的冠状面楔状畸形;然而,这项工作大多倾向于孤立地检查参数,往往忽视了冠状楔畸形与矢状生理曲率变化之间的关键关系6,7,8。

Some studies suggested that the Cobb angle may consist of contributions from both vertebrae and disc wedging angles9,10. This deformation may be a crucial factor in the progression of spinal curvature, as it can affect the mechanical properties of the spine, leading to pathological spinal bending. Additionally, the sagittal physiological curvature of the spine plays a vital role in the overall stability and load distribution of the spine11,12.

一些研究表明,Cobb角可能包括椎骨和椎间盘楔入角的贡献9,10。这种变形可能是脊柱弯曲进展的关键因素,因为它会影响脊柱的机械性能,导致病理性脊柱弯曲。此外,脊柱的矢状生理曲率在脊柱的整体稳定性和载荷分布中起着至关重要的作用11,12。

Changes in sagittal curvature may exacerbate spinal deformity and impact the functional abilities of the patient13. Various hypotheses have been proposed regarding the development of scoliosis14,15,16,17,18, each presenting diverse perspectives on the underlying mechanisms and interrelationships among factors such as vertebral rotation, changes in sagittal curvature, coronal scoliosis, and anterior column growth.

矢状面曲率的变化可能会加剧脊柱畸形并影响患者的功能13。关于脊柱侧弯的发展已经提出了各种假设[14,15,16,17,18],每种假设都对脊柱旋转,矢状曲率变化,冠状脊柱侧弯和前柱生长等因素之间的潜在机制和相互关系提出了不同的观点。

The complexity of the human body often renders these.

人体的复杂性通常会导致这些。

Data availability

数据可用性

The datasets analysed during the current study are available from the corresponding author on reasonable request.

本研究期间分析的数据集可根据合理要求从通讯作者处获得。

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Download referencesAuthor informationAuthor notesYi Shen, Feipeng Qin and Yingsen Pan contributed equally to this work and share first authorship.Xiaoming Li and Xiaoming Ying contributed equally and should be considered as joint corresponding authors.Authors and AffiliationsThe 3rd clinical medical college of Zhejiang Chinese Medical University, Hangzhou, ChinaYi Shen, Feipeng Qin & Yingsen PanHangzhou Hospital of Traditional Chinese Medicine, Hangzhou, ChinaHaoyang ZhangZhejiang Chinese Medical University, Hangzhou, ChinaNdalyolusha Tileinge HapulileTuina Department, The 3rd affiliated hospital of Zhejiang Chinese Medical University, Hangzhou, ChinaShuailin Li, Xin Ye, Xiaoming Li & Xiaoming YingAuthorsYi ShenView author publicationsYou can also search for this author in.

下载参考文献作者信息作者笔记沈,秦飞鹏和潘英森对这项工作做出了同样的贡献,并分享了第一作者身份。李晓明和英晓明贡献相等,应被视为联合通讯作者。作者和所属单位浙江中医药大学第三临床医学院,杭州,中国,沉仪,秦飞鹏和英森,杭州,杭州,杭州中医医院,杭州,张浩阳,浙江中医药大学,杭州,杭州,浙江中医药大学第三附属医院,杭州,中国,李树林,叶欣,李晓明和英晓明作者,作者:ShenView作者出版物你也可以在中搜索这位作者。

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PubMed Google ScholarContributionsY. X. M linked the cohort and oversaw data management. S. Y analyzed the data and drafted the manuscript. Q. F. P and P. Y. S assisted in editing and proofreading manuscripts, collecting references. All authors participated in the design of the study, interpretation of the results, and approved the final manuscript.Corresponding authorsCorrespondence to.

PubMed谷歌学术贡献。十、 M将队列联系起来并监督数据管理。S、 Y分析了数据并起草了手稿。Q、 F.P和P.Y.S协助编辑和校对手稿,收集参考文献。所有作者都参与了研究的设计,结果的解释,并批准了最终稿件。通讯作者通讯。

Xiaoming Li or Xiaoming Ying.Ethics declarations

李晓明或英晓明。道德宣言

Competing interests

相互竞争的利益

The authors declare no competing interests.

作者声明没有利益冲突。

Informed consent

知情同意书

Due to the retrospective nature of the study, the ethics committee at the 3rd affiliated hospital of Zhejiang Chinese Medical University waived the need of obtaining informed consent.

由于该研究具有回顾性,浙江中医药大学附属第三医院伦理委员会放弃了获得知情同意的需要。

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Reprints and permissionsAbout this articleCite this articleShen, Y., Qin, F., Pan, Y. et al. Correlation between coronal wedge deformity and sagittal spinal curvature in adolescent idiopathic scoliosis: a retrospective analysis.

转载和许可本文引用本文Shen,Y.,Qin,F.,Pan,Y。等人。青少年特发性脊柱侧凸冠状楔畸形与矢状脊柱曲度的相关性:回顾性分析。

Sci Rep 14, 29038 (2024). https://doi.org/10.1038/s41598-024-80704-8Download citationReceived: 29 June 2024Accepted: 21 November 2024Published: 23 November 2024DOI: https://doi.org/10.1038/s41598-024-80704-8Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a shareable link is not currently available for this article.Copy to clipboard.

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KeywordsSpineAdolescent idiopathic scoliosisCobb angleWedge deformityThoracic kyphosisLumbar lordosisCorrelation analysis

关键词松果体青少年特发性脊柱侧凸Cobb角楔畸形胸腰椎后凸前凸相关分析