美国疾病控制与预防中心确认美国首例严重H5N1禽流感病例-动脉网

CDC Confirms First-Ever Severe Case of H5N1 Bird Flu in the United States

GeneOnline 等信源发布 2024-12-18 12:03

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by Denisse Sandoval

Denisse Sandoval

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Image source: AdobeThe Centers for Disease Control and Prevention (CDC) has confirmed the first severe case of H5N1 avian influenza in Louisiana, United States. Health officials in the state reported that the patient, now hospitalized, likely contracted the virus through contact with backyard poultry.

图片来源：美国疾病控制与预防中心（CDC）已确认美国路易斯安那州首例H5N1禽流感重症病例。该州卫生官员报告称，该患者目前住院，可能通过与后院家禽接触而感染病毒。

Health officials reported this case on December 13, identifying it as part of a global pattern of severe illness linked to poultry exposure. H5N1 D1.1 Genotype Identified in Louisiana Patient, CDC to Isolate Virus from Clinical SpecimensViral genome analysis conducted of the H5N1 avian influenza virus from the patient indicates it belongs to the D1.1 genotype.

卫生官员于12月13日报告了该病例，将其确定为与家禽接触有关的全球严重疾病模式的一部分。在路易斯安那州患者中鉴定出H5N1 D1.1基因型，CDC从临床标本中分离出病毒。对患者的H5N1禽流感病毒进行的病毒基因组分析表明，它属于D1.1基因型。

This genotype has been recently identified in wild birds, poultry in the United States, and human cases in British Columbia, Canada, and Washington state. The B3.13 genotype differs and has been detected in dairy cows, sporadic human cases across multiple states, and some poultry outbreaks in the U.S.

最近在美国的野生鸟类，家禽以及不列颠哥伦比亚省，加拿大和华盛顿州的人类病例中发现了这种基因型。B3.13基因型不同，已在奶牛，多个州的零星人类病例以及美国的一些家禽疫情中检测到。

Reports indicate that the B3.13 genotype causes mild symptoms such as conjunctivitis. The CDC is conducting further genomic sequencing and attempting to isolate the virus from the patient’s clinical specimens.First U.S. Case of H5N1 Linked to Backyard Poultry Exposure in 2024CDC officials are investigating the source of the H5N1 infection in Louisiana and have determined that exposure to sick and dead birds in backyard flocks infected the patient.

报告表明，B3.13基因型会引起结膜炎等轻度症状。CDC正在进行进一步的基因组测序，并试图从患者的临床标本中分离出病毒。2024CDC官员正在调查路易斯安那州H5N1感染源，并确定后院禽群中病禽和死禽的接触感染了该患者。

This marks the first U.S. case of H5N1 linked to backyard poultry exposure. Sporadic severe cases of H5N1 in humans have occurred in other countries during 2024 and previous years, sometimes resulting in death. No evidence of person-to-person transmission of H5N1 has been detected. The CDC states that the immediate risk to public health from H5N1 remains low.Demetre Daskalakis.

这是美国首例与后院家禽接触有关的H5N1病例。2024年和前几年，其他国家也发生了零星的人类H5N1严重病例，有时会导致死亡。没有发现H5N1人与人之间传播的证据。疾病预防控制中心表示，H5N1对公众健康的直接风险仍然很低。德米特里·达斯卡拉基斯。

“These two cases do not change CDC’s current risk assessment for the general population. The large number of animals—birds and mammals—infected with H5 bird flu increases the risk of the virus potentially infecting people and potentially adapting to cause human-to-human spread, reemphasized Dimitri Daskalakis. .

“这两起病例并没有改变疾病预防控制中心目前对普通人群的风险评估。Dimitri Daskalakis再次强调，大量感染H5禽流感的动物、鸟类和哺乳动物增加了病毒感染人类的风险，并可能导致人与人之间的传播。”。

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Denisse Sandoval

Denise Sandoval