Share to FacebookShare to TwitterShare to LinkedinSana Alajmovic and Tore Bengtsson, cofounders of Sigrid Therapeutics, which develops natural, ... [+] non-drug solutions for prediabetes progression and weight controlSigrid Therapeutics, manages diabetes and obesity with non-drug solutions

分享给FacebookShare分享给Twitter分享给LinkedinSana Alajmovic和Tore Bengtsson，Sigrid Therapeutics的联合创始人，该公司开发自然。。。[+]用于糖尿病前期进展和体重控制的非药物解决方案Sigrid Therapeutics，使用非药物解决方案管理糖尿病和肥胖症

Sigrid Therapeutics, a Swedish-based company founded in 2014 by Sana Alajmovic and Tore Bengtsson, is on a mission to prevent chronic diseases such as type 2 diabetes. After raising $20 million and almost a decade of researching, engineering, and proving silica’s safety and effectiveness, the company launched Glucose Stabiliser on November 14, 2023..

Sigrid Therapeutics是一家瑞典公司，由Sana Alajmovic和Tore Bengtsson于2014年成立，其使命是预防2型糖尿病等慢性疾病。在筹集了2000万美元以及近十年的研究、工程和证明二氧化硅的安全性和有效性后，该公司于2023年11月14日推出了葡萄糖稳定剂。。

Noncommunicable diseases—such as diabetes—are responsible for the majority (70%) of deaths worldwide. These chronic diseases are not transmitted between individuals and are caused by a mix of factors including genetics, physiology, environment, and behaviors.

糖尿病等非传染性疾病是全球大多数（70%）死亡的原因。这些慢性疾病不会在个体之间传播，是由多种因素引起的，包括遗传，生理，环境和行为。

At first investors didn’t see the value of preventing diseases. However, increased focus on early detection, awareness of prediabetes and societal costs, and technological advancements have opened doors for innovative approaches, making preventive tools an attractive investment opportunity. The Covid-19 pandemic also highlighted the importance of self-care and managing blood sugar levels, further increasing market potential..

起初，投资者没有看到预防疾病的价值。然而，人们越来越重视早期发现，对糖尿病前期和社会成本的认识以及技术进步为创新方法打开了大门，使预防工具成为一个有吸引力的投资机会。新型冠状病毒肺炎也突出了自我保健和管理血糖水平的重要性，进一步增加了市场潜力。。

How Sigrid Therapeutics Manages Prediabetes With Silica

Sigrid Therapeutics如何用二氧化硅治疗糖尿病前期

In 2008, Bengtsson started to research how silica—a mineral in some grasses, that has the ability to absorb digestive enzymes in the gut—could be engineered to slow down digestion and reduce the absorption of carbs and fats into the bloodstream. Doing so would result in lower blood sugar and cholesterol levels and, potentially, aiding in weight loss..

2008年，Bengtsson开始研究如何设计二氧化硅（一些禾本科植物中的一种矿物质，具有吸收肠道消化酶的能力）来减缓消化，减少碳水化合物和脂肪向血液中的吸收。这样做会降低血糖和胆固醇水平，并可能有助于减肥。。

Alajmovic and Bengtsson met in 2013. In 2014, the pair founded Sigrid Therapeutics. Sigrid is a female Viking name that means beautiful victory. “The victory that we envisioned in 2014, when we started the company, is that no one should fall sick with chronic lifestyle diseases, such as type 2 diabetes and obesity,” said Alajmovic.

Alajmovic和Bengtsson于2013年会面。2014年，两人成立了Sigrid Therapeutics。西格丽德是一个维京女性名字，意味着美丽的胜利。Alajmovic说：“我们在2014年创办该公司时设想的胜利是，任何人都不应该患上慢性生活方式疾病，如2型糖尿病和肥胖症。”。

She became CEO and Bengtsson chief scientific officer..

她成为CEO兼Bengtsson首席科学官。。

MORE FOR YOUTaylor Swift And Other Jet-Setters Can Send A Climate MessageLooking For A Career Change In 2024? 5 Steps For A YOLO Strategy.The World’s Best Rums-2023 Competition EditionSigrid Therapeutics team. The company develops natural, non-drug solutions for prediabetes ... [+] progression and weight controlSigrid Therapeutics, manages diabetes and obesity with non-drug solutions.

更多关于青年的信息泰勒·斯威夫特（TaylorSwift）和其他喷气式飞机驾驶员可以发送一条气候信息，寻找2024年的职业变化？YOLO战略的5个步骤。世界最佳Rums-2023竞赛编辑Sigrid Therapeutics团队。该公司为糖尿病前期开发天然的非药物解决方案。。。[+]进展和体重控制Sigrid Therapeutics，用非药物解决方案管理糖尿病和肥胖症。

The company has spent almost a decade researching, engineering, conducting clinical studies, and scaling up production of silica. It is only this year that the company launched its first product—Glucose Stabiliser.

该公司花费了近十年的时间进行研究、工程设计、临床研究以及扩大二氧化硅的生产规模。直到今年，该公司才推出了首款产品葡萄糖稳定剂。

Its chief ingredient, SiPore21, helps lower blood sugar, body weight, and cholesterol. SiPore uses mesoporous silica particles (MSPs) to create a molecular sieve that physically prevents the interaction between digestive enzymes and food. This results in reduced food breakdown into absorbable units, making it a promising preventive supplement for prediabetes and type 2 diabetes.

它的主要成分SiPore21有助于降低血糖、体重和胆固醇。SiPore使用介孔二氧化硅颗粒（MSPs）产生一种分子筛，可以物理上阻止消化酶与食物之间的相互作用。这导致食物分解成可吸收单位的减少，使其成为糖尿病前期和2型糖尿病的有前景的预防补充剂。

SiPore21 is patented in the U.S, European Union, Canada, Australia, Japan and Israel, among other countries..

SiPore21在美国、欧盟、加拿大、澳大利亚、日本和以色列等国家拥有专利。。

Silica is a natural mineral composed of silicon and oxygen, two of the most abundant elements on earth. Its unique architecture and chemistry give it its functional properties, making SiPore gentle for both the human body and the environment.

二氧化硅是一种天然矿物，由硅和氧组成，硅和氧是地球上含量最丰富的两种元素。它独特的结构和化学性质赋予了它的功能特性，使SiPore对人体和环境都很温和。

In the U.S., SiPore21—the main ingredient of Sigrid’s products—is considered a supplement. In the E.U., SiPore21 is considered a medical device. Medical devices have many more regulatory hurdles so the company launched in the U.S. Miami, Florida was chosen for its U.S. headquarters for these reasons:.

在美国，Sigore21 Sigrid产品的主要成分被认为是一种补充剂。在欧盟，SiPore21被认为是一种医疗设备。医疗器械有更多的监管障碍，因此选择在美国佛罗里达州迈阿密成立的公司作为其美国总部，原因如下：。

Many people over the age of 65 live in Florida. As we get older, our bodies become more susceptible to type 2 diabetes. Research suggests that 25% of adults above the age of 65 are living with type 2 diabetes, while half of seniors have been diagnosed with prediabetes.

许多65岁以上的人住在佛罗里达州。随着年龄的增长，我们的身体变得更容易患2型糖尿病。研究表明，65岁以上的成年人中有25%患有2型糖尿病，而一半的老年人被诊断出患有糖尿病前期。

Miami has become the fourth largest tech hub in the U.S. with a growing investor investors.

迈阿密已成为美国第四大科技中心，投资者不断增加。

Its weather and quality of life makes it easier to retain talent.

它的天气和生活质量使它更容易留住人才。

Miami #1 U.S. City of Wellness.

迈阿密#美国健康之都。

It is closer to Stockholm than Los Angeles.

它比洛杉矶更靠近斯德哥尔摩。

While available directly to consumers on its website, a focused retail distribution effort is underway in Florida. The company launched on November 14, 2023, and is working with nutrition influencers and wholesalers in Florida.

虽然可以在其网站上直接向消费者提供，但佛罗里达州正在进行一项重点零售分销工作。该公司于2023年11月14日成立，目前正在与佛罗里达州的营养影响者和批发商合作。

If Finding Venture Capital Was Easy, Everyone Would Raise Capital

如果很容易找到风险投资，每个人都会筹集资金

An early challenge was raising capital. In 2014, Alajmovic was told by investors “There's no money in prevention. We only care when there is a diagnosis.” Consultants and physicians told her to target Type 2 diabetics who had a cardiovascular event.

早期的挑战是筹集资金。2014年，投资者告诉Alajmovic“预防没有钱。我们只关心有诊断的时候。”顾问和医生告诉她要针对患有心血管事件的2型糖尿病患者。

“I grew up with a prediabetic father, who became diabetic,” said Alajmovic. “I was always confused why we're living in a society, which manages diseases reactively rather than being proactive.”

Alajmovic说：“我和一个糖尿病前期的父亲一起长大，后来患上了糖尿病。”。“我一直很困惑，为什么我们生活在一个对疾病进行反应性管理而不是积极主动的社会。”

Alajmovic is a refugee from Bosnia and Herzegovina who migrated to Sweden with her family when she was 5 years old. The family had lost nearly everything in the war. She developed an underdog mentality—a strong determination to overcome obstacles and succeed despite the odds being stacked against her.

Alajmovic是一名来自波斯尼亚和黑塞哥维那的难民，5岁时随家人移居瑞典。这家人在战争中几乎失去了一切。她形成了一种失败者的心态——克服障碍并取得成功的坚定决心，尽管困难重重。

“I'm going to do this even more now, just because someone tells me it can't be done,” said Alajmovic..

“我现在要做得更多，因为有人告诉我这是不可能的，”阿拉伊莫维奇说。。

“One thing that helped us was when a company with a prediabetes asset made a huge deal with one of the world's largest consumer health and nutrition companies,” said Alajmovic. “It was incredibly helpful to have a peer to point to.”

Alajmovic说：“帮助我们的一件事是，一家拥有糖尿病前期资产的公司与世界最大的消费者健康和营养公司之一达成了巨额交易。”。“有一个同伴指点真是太有帮助了。”

Fortunately, the landscape for early-stage investment in type 2 diabetes prevention has undergone significant transformations since Sigid formed in 2014. Key shifts include:

幸运的是，自2014年Sigid成立以来，2型糖尿病预防的早期投资格局发生了重大变化。关键转变包括：

An increase in investment driven by growing awareness of the prevalence of diabetes and its societal costs.

对糖尿病患病率及其社会成本的认识不断提高，导致投资增加。

Technological advancements in areas like AI, digital health, and biotechnologies opened doors for innovative approaches.

人工智能、数字健康和生物技术等领域的技术进步为创新方法打开了大门。

From managing existing cases, focus has shifted towards early detection and lifestyle modification.

从管理现有病例开始，重点转向早期发现和改变生活方式。

Expanding market potential for preventive tools and early intervention is now attracting investors seeking high returns.

预防工具和早期干预的市场潜力不断扩大，现在吸引了寻求高回报的投资者。

The Covid-19 pandemic raised awareness of the importance of self-care and taking charge of your health. “Now everyone knows about blood sugar peaks and glucose monitors have become mainstream,” said Alajmovic.

新型冠状病毒肺炎的流行提高了人们对自我保健和健康管理重要性的认识。Alajmovic说：“现在每个人都知道血糖峰值，血糖监测仪已经成为主流。”。

The company has raised $20 million from Joyous Partners, a San Francisco VC, family offices, high-net-worth individuals, and the Swedish state venture capital fund. These investors know that healthcare products take more time to bring to market and are in it for the long haul.

该公司已从Joyous Partners、旧金山风投、家族理财办公室、高净值个人和瑞典国家风险投资基金筹集了2000万美元。这些投资者知道，医疗保健产品需要更多的时间才能推向市场，而且是长期的。

How are you going to use market shifts to build your business?

您将如何利用市场变化来建立业务？