Using

使用

advanced computational strategies and topology optimization, OptimalPSI is focused on developing patient-specific spinal fusion implants.

先进的计算策略和拓扑优化，OptimalPSI 专注于开发患者特定的脊柱融合植入物。

The ETH spin-off OptimalPSI has obtained CHF 150,000 from Venture Kick to prepare for its US market entry.

ETH分拆公司OptimalPSI已从Venture Kick获得15万瑞士法郎，以准备进入美国市场。

Lower back pain is one of the most prevalent health issues in Switzerland. When conservative treatments fail, spinal fusion surgery is often required, typically employing standard, off-the-shelf implants. However, over 50% of patients suffer from implant subsidence, the major postoperative complication for this type of surgery that prolongs recovery by months and in the worst case requires revision surgery. .

下背部疼痛是瑞士最常见的健康问题之一。当保守治疗失败时，通常需要进行脊柱融合手术，这通常使用标准的现成植入物。然而，超过50%的患者遭受植入物下沉的困扰，这是此类手术的主要术后并发症，会使恢复时间延长数月，最严重的情况下甚至需要进行翻修手术。

OptimalPSI

最优PSI

addresses this challenge by applying topology optimization and computational engineering to design and optimize patient-specific spinal fusion implants. By integrating patient-specific optimization and 3D printing, the company offers spinal fusion implants with a perfect fit, geometrically and structurally, improving the predictability of the surgical outcome, and reducing the risk of subsidence of healthcare expenses. .

通过应用拓扑优化和计算工程来设计和优化患者特定的脊柱融合植入物，从而应对这一挑战。通过整合患者特定的优化和3D打印技术，该公司提供了在几何和结构上完美贴合的脊柱融合植入物，提高了手术结果的可预测性，并降低了医疗费用沉没的风险。

The startup is now moving toward clinical application and commercialization, initially targeting the US market, focusing on patients with degenerative conditions, particularly osteoporosis. The potential annual revenue for this market only is estimated at USD 1.73 billion.  The fresh funding from Venture Kick allows the company to .

这家初创公司现在正朝着临床应用和商业化方向发展，最初瞄准美国市场，重点关注退行性疾病患者，特别是骨质疏松症。仅这一市场的潜在年收入估计为17.3亿美元。来自Venture Kick的新资金使该公司能够继续推进。

prepare for its US market entry and continue developing toward the design freeze milestone. Meanwhile, the startup is in the process of incorporation

为进入美国市场做准备，并继续朝着设计冻结里程碑迈进。同时，这家初创公司正在注册过程中。

Leading OptimalPSI are CEO Dr. Thijs Smit and CTO Wolfgang Rubin, both scientists from ETH Zurich. Their combined expertise in computational design and medical technology is driving the development of next-generation spinal fusion implants to improve patient care and surgical outcomes.

领先的OptimalPSI公司由首席执行官蒂伊斯·斯密特博士和首席技术官沃尔夫冈·鲁宾领导，他们都是来自苏黎世联邦理工学院的科学家。他们在计算设计和医疗技术方面的综合专业知识正在推动下一代脊柱融合植入物的开发，以改善患者护理和手术效果。

“The support from Venture Kick allowed us to make huge steps in our business development,” commented CEO Thijs Smit. “Also, the Kick camps have been ‘kicking’ us to a higher level every time.”

“Venture Kick的支持使我们在业务发展上迈出了巨大的步伐，”首席执行官Thijs Smit评论道。“此外，Kick训练营每次都将我们推向更高的水平。”

(Press release/RAN)

（新闻稿/无线接入网）

OptimalPSI team (from left to right): Wolfgang Rubin, Thijs Smit, Xiaoyu Du, and Stephen Ferguson

OptimalPSI 团队（从左到右）：Wolfgang Rubin、Thijs Smit、杜晓宇和 Stephen Ferguson

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