SAN DIEGO, Jan. 03, 2024 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (Nasdaq: BNGO), today announced a publication outlining the addition of optical genome mapping (OGM) to the International System for Human Cytogenomic Nomenclature (ISCN). The OGM nomenclature is expected to be published in the 2024 edition of the ISCN guide, a reference volume covering ISCN nomenclature that is utilized worldwide by cytogeneticists, molecular biologists, technicians, and students.

圣地亚哥，2024年1月3日（环球通讯社）--Bionano Genomics，Inc.（纳斯达克：BNGO）今天宣布了一份出版物，概述了将光学基因组图谱（OGM）添加到国际人类细胞基因组命名系统（ISCN）中。OGM命名法预计将在2024年版的ISCN指南中发布，该指南是一本参考书，涵盖了细胞遗传学家，分子生物学家，技术人员和学生在世界范围内使用的ISCN命名法。

ISCN nomenclature is an international standard covering structural and numerical chromosomal aberrations detected by traditional cytogenetic and molecular techniques and is recognized by College of American Pathologists (CAP), Clinical Laboratory Improvement Amendments (CLIA), and other bodies responsible for laboratory standards around the world.

ISCN命名法是一项国际标准，涵盖了通过传统细胞遗传学和分子技术检测到的结构和数字染色体畸变，并得到美国病理学家学院（CAP），临床实验室改进修正案（CLIA）和其他负责世界各地实验室标准的机构的认可。

Having a universal, accepted naming convention to describe the genetic variants that OGM detects is critical for unambiguous reporting and accurate dissemination of research data, however there is currently no established standard nomenclature for optical genome mapping. The ISCN Standing Committee, which is comprised of an international group of experts nominated by their peers, formulated an OGM nomenclature and shared that with an international group of OGM users for their feedback.

拥有一个通用的，公认的命名约定来描述OGM检测到的遗传变异，对于明确报告和准确传播研究数据至关重要，但是目前尚无用于光学基因组作图的标准命名法。ISCN常设委员会由同行提名的国际专家组组成，制定了OGM命名法，并与国际OGM用户组分享了该命名法，以供其反馈。

The latest edition of the ISCN guide, last updated in 2020, is expected to include standard nomenclature used to describe any genomic rearrangement identified by OGM, as well as specific ISCN examples for the different types of numerical and structural rearrangements detected by the workflow. This nomenclature can be used by laboratories to report their findings.

最新版本的ISCN指南（最后一次更新于2020年）预计将包括用于描述OGM识别的任何基因组重排的标准命名法，以及工作流程检测到的不同类型的数字和结构重排的特定ISCN示例。实验室可以使用这种命名法来报告他们的发现。

“We are pleased to see the ISCN committee recognize OGM through its inclusion in their nomenclature, which has been a sta.

“我们很高兴看到ISCN委员会通过将OGM纳入其命名法（这是一个sta）来认可OGM。