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脊髓损伤的预后血浆生物标志物

Prognostic plasma biomarkers for spinal cord injury

Nature 等信源发布 2025-03-10 22:24

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Measurements of neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP) and contactin 1 (CNTN1) in plasma can provide useful prognostic information following traumatic spinal cord injury (SCI), according to new research published in

根据发表在《》上的新研究,血浆中神经丝轻链(NfL)、胶质纤维酸性蛋白(GFAP)和接触蛋白1(CNTN1)的测量可为创伤性脊髓损伤(SCI)后的预后提供有用信息。

Annals of Neurology

神经病学年鉴

.

The study included 37 patients with traumatic SCI and 22 healthy control individuals. Plasma samples were collected at various time points up to 18 weeks following injury.

该研究包括37名创伤性脊髓损伤患者和22名健康对照个体。在损伤后最多18周内,于不同时间点采集血浆样本。

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References

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Original article

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Fraussen, J. et al. Longitudinal plasma biomarker profiles predict neurological outcome in traumatic spinal cord injury.

弗劳森,J. 等。纵向血浆生物标志物谱预测创伤性脊髓损伤的神经学结局。

Ann. Neurol.

神经学年鉴

https://doi.org/10.1002/ana.27198

https://doi.org/10.1002/ana.27198

(2025)

(2025)

Article

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PubMed

PubMed

Google Scholar

谷歌学术

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Nature Reviews Neurology

自然评论神经学

http://www.nature.com/nrneurol/

http://www.nature.com/nrneurol/

Heather Wood

希瑟·伍德

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Heather Wood

希瑟·伍德

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Heather Wood

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Wood, H. Prognostic plasma biomarkers for spinal cord injury.

伍德,H. 脊髓损伤的预后血浆生物标志物。

Nat Rev Neurol

自然综述:神经病学

(2025). https://doi.org/10.1038/s41582-025-01075-w

(2025). https://doi.org/10.1038/s41582-025-01075-w

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10 March 2025

2025年3月10日

DOI

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https://doi.org/10.1038/s41582-025-01075-w

https://doi.org/10.1038/s41582-025-01075-w

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