TUESDAY, March 18, 2025 -- For patients with severe oral commissure droop from facial nerve damage undergoing

2025年3月18日，星期二——对于因面部神经损伤导致严重嘴角下垂的患者进行手术时

surgery

手术

, botulinum toxin type A (BoNT-A) treatment helps to alleviate muscle hyperactivity, leading to improvement in facial asymmetry, according to a study published in the March issue of

，根据发表在3月份一期的研究，A型肉毒杆菌毒素（BoNT-A）治疗有助于缓解肌肉过度活跃，从而改善面部不对称。

Plastic and Reconstructive Surgery

整形外科与重建外科

.

。

Hao Ma, M.D., from Shanghai Ninth People's Hospital, and colleagues examined the impact of BoNT-A treatment on the unaffected side in 38 patients with severe oral commissure droop from facial nerve damage with respect to facial symmetry and brain connectivity. Participants were divided into two groups: those who did and did not receive BoNT-A injections on the unaffected side (20 and 18 patients, respectively)..

上海第九人民医院的马昊医生及其团队研究了BoNT-A治疗对38名因面神经损伤导致严重口角下垂患者的健侧的影响，重点关注面部对称性和大脑连通性。参与者被分为两组：接受和未接受健侧BoNT-A注射的患者（分别为20名和18名）。

The researchers found that BoNT-A treatment improved facial symmetry and induced significant modifications in brain functional network connectivity. The modifications extended beyond the sensorimotor network, involving high-level cognitive processes. There was a significant correlation between functional network connectivity and the degree of asymmetry..

研究人员发现，BoNT-A治疗改善了面部对称性，并诱导了大脑功能网络连接的显著变化。这些变化超出了感觉运动网络，涉及高级认知过程。功能网络连接与不对称程度之间存在显著相关性。

'BoNT-A treatment appears to promote significant modifications in functional brain network connectivity, thereby sustaining the positive effects of BoNT-A,' the authors write. 'Our findings imply that the facial asymmetry is linked to the characteristics of large-scale functional networks.'

“BoNT-A治疗似乎促进了功能性脑网络连接的显著变化，从而维持了BoNT-A的积极效果，”作者写道。“我们的研究结果表明，面部不对称性与大规模功能网络的特性有关。”

Abstract/Full Text

摘要/全文

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TUESDAY, March 18, 2025 -- The combination of machine learning and a portable system can effectively measure multiple aspects of motor function to identify mild cognitive...

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